URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=30038
Proper Citation: RRID:MMRRC_030038-UCD
Description: Mus musculus with name B6;129S-Sphk1tm2Cgh/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Developmental Biology, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased bone marrow cell number [MP:0000333]| abnormal lymphocyte cell number [MP:0000717]| abnormal lymphatic vessel morphology [MP:0001879]| hemorrhage [MP:0001914]| abnormal T cell differentiation [MP:0002145]| abnormal lymph node morphology [MP:0002339]| abnormal Peyer's patch T cell area morphology [MP:0002392]| abnormal immune serum protein physiology [MP:0002723]| increased vascular permeability [MP:0003070]| abnormal leukocyte migration [MP:0003156]| decreased B cell number [MP:0005017]| decreased T cell number [MP:0005018]| increased NK cell number [MP:0008044]| decreased NK cell number [MP:0008045]| abnormal NK cell differentiation [MP:0008053]| abnormal thymus cell ratio [MP:0008827]| decreased splenocyte number [MP:0009339]
Affected Gene: Sphk1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)