Alignments
Protein Domains
ASAP ID
Names
ldcC
LDC2
ldcH
ldc
JW0181
ECK0185
b0186
Product
lysine decarboxylase 2
Type
CDS
Location
#
Contig
Strand
Left
Right
Length (b.p.)
Length (a.a.)
1
Chromosome
forward
209679
211820
2142
714
Sequence
Context
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Protein Families
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Family
Annotated
IPR000310 (IPR000310 Orn/Lys/Arg decarboxylase, major domain)
Apr 2008
IPR008286 (IPR008286 Orn/Lys/Arg decarboxylase, C-terminal)
Apr 2008
IPR005308 (IPR005308 Orn/Lys/Arg decarboxylase, N-terminal)
Apr 2008
IPR015424 (IPR015424 Pyridoxal phosphate-dependent transferase)
Apr 2008
IPR015422 (IPR015422 Pyridoxal phosphate-dependent transferase, small domain)
Apr 2008
IPR011193 (IPR011193 Ornithine/lysine/arginine decarboxylase)
Apr 2008
IPR015421 (IPR015421 Pyridoxal phosphate-dependent transferase, major domain)
Apr 2008
IPR036633 (IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily)
Jul 2018
PF03709 (PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain)
Jul 2018
PF01276 (PF01276 Orn/Lys/Arg decarboxylase, major domain)
Jul 2018
PF03711 (PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain)
Jul 2018
Gene Ontology
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Type
Annotation
Evidence
Annotated
GO biological process
GO:0006520 cellular amino acid metabolic process
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR011193 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO biological process
GO:0016052 carbohydrate catabolic process
Ontology Mapping -
Source and Dest Ontology: MultiFun to GO
Mar 2004
GO biological process
GO:0006096 glycolytic process
Ontology Mapping -
Source and Dest Ontology: MultiFun to GO
Mar 2004
GO cellular component
GO:0005737 cytoplasm
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR011193 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO molecular function
GO:0030170 pyridoxal phosphate binding
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR015422 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO molecular function
GO:0016831 carboxy-lyase activity
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR005308 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO molecular function
GO:0003824 catalytic activity
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR000310 Reference: Escherichia coli K-12 MG1655
Apr 2008
Annotations
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Type
Annotation
Evidence
Annotated
name
ldcC
Published Annotation -
GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Oct 1998
synonym
ECK0185
Published Annotation -
PubMed ID: 16397293
Jan 2006
synonym
JW0181
Published Annotation -
PubMed ID: 16397293
Jan 2006
synonym
ldc
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
synonym
LDC2
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
synonym
ldcH
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
locus tag
b0186
Unique Identifier -
Origin: Guy Plunkett III, guy@genome.wisc.edu
May 2004
product
lysine decarboxylase 2
Published Annotation -
PubMed ID: 16397293
Reference: Escherichia coli K-12
Oct 2021
alternate product name
lysine decarboxylase 2, constitutive
Published Annotation -
GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Jan 2006
protein family
IPR008286 Orn/Lys/Arg decarboxylase, C-terminal
Protein Sequence Similarity -
InterPro Domain: IPR008286
Reference: Escherichia coli K-12 MG1655
Apr 2008
protein family
IPR000310 Orn/Lys/Arg decarboxylase, major domain
Protein Sequence Similarity -
InterPro Domain: IPR000310
Reference: Escherichia coli K-12 MG1655
Apr 2008
protein family
IPR005308 Orn/Lys/Arg decarboxylase, N-terminal
Protein Sequence Similarity -
InterPro Domain: IPR005308
Reference: Escherichia coli K-12 MG1655
Apr 2008
protein family
IPR015422 Pyridoxal phosphate-dependent transferase, small domain
Protein Sequence Similarity -
InterPro Domain: IPR015422
Reference: Escherichia coli K-12 MG1655
Apr 2008
protein family
IPR015424 Pyridoxal phosphate-dependent transferase
Protein Sequence Similarity -
InterPro Domain: IPR015424
Reference: Escherichia coli K-12 MG1655
Apr 2008
protein family
PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain
Protein Sequence Similarity -
PFAM Model Name: PF03709
Reference: Escherichia coli K-12 MG1655
Jul 2018
protein family
IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily
Protein Sequence Similarity -
InterPro Domain: IPR036633
Reference: Escherichia coli K-12 MG1655
Jul 2018
protein family
IPR011193 Ornithine/lysine/arginine decarboxylase
Protein Sequence Similarity -
InterPro Domain: IPR011193
Reference: Escherichia coli K-12 MG1655
Apr 2008
protein family
PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain
Protein Sequence Similarity -
PFAM Model Name: PF03711
Reference: Escherichia coli K-12 MG1655
Jul 2018
protein family
IPR015421 Pyridoxal phosphate-dependent transferase, major domain
Protein Sequence Similarity -
InterPro Domain: IPR015421
Reference: Escherichia coli K-12 MG1655
Apr 2008
protein family
PF01276 Orn/Lys/Arg decarboxylase, major domain
Protein Sequence Similarity -
PFAM Model Name: PF01276
Reference: Escherichia coli K-12 MG1655
Jul 2018
EC number
4.1.1.18
Published Annotation -
Swiss-Prot Accession Number: P52095
Feb 2006
EC number
4.1.1.-
Published Annotation -
Database Name: EC2GO: GO:0016831 Reference: Escherichia coli K-12 MG1655
Jul 2018
MultiFun
1.1.1
(metabolism; carbon utilization; carbon compounds )
Published Annotation -
MultiFun Database Name: MultiFun
Feb 2002
MultiFun
1.3.1
(metabolism; energy metabolism, carbon; glycolysis )
Published Annotation -
MultiFun Database Name: MultiFun
Feb 2002
codon start
1
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
db xref
UniProtKB:P52095
Published Annotation -
Swiss-Prot Accession Number: P52095
Jan 2005
db xref
GeneID:944887
Published Annotation -
Entrez Gene Database ID: 944887
Reference: Escherichia coli K-12 MG1655
Jun 2009
db xref
UniProtKB/Swiss-Prot:P52095
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
db xref
ASAP:ABE-0000633
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
db xref
GI:1786384
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
db xref
EcoGene:EG13219
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
function
enzyme; Energy metabolism, carbon: Pyruvate dehydrogenase
Published Annotation -
GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Oct 1998
molecular interaction
Interacts with the product of cadA ASAP:13526:(interacting residues not known); by MALDI-TOF and LC-MS
Experimental -
PubMed ID: 15690043
Reference: Escherichia coli K-12 W3110
Mar 2005
note
GO_process: GO:0006096 - glycolysis; GO_process: GO:0016052 - carbohydrate catabolic process
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
protein id
AAC73297.1
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
subcellular localization
Unknown
Predicted by PSORTb -
PSORTb Final_Score: 2.00 Reference: Escherichia coli K-12 MG1655
Feb 2008
subsystem
component of in silico model iMC1010
Experimental -
PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655
Mar 2009
subsystem
component of in silico model iJR904
Experimental -
PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655
Feb 2009
subsystem
component of in silico model iAF1260
Experimental -
PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655
Jan 2009
transl table
11
Published Annotation -
GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
GO biological process
GO:0016052 carbohydrate catabolic process
Ontology Mapping -
Source and Dest Ontology: MultiFun to GO
Mar 2004
GO biological process
GO:0006520 cellular amino acid metabolic process
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR011193 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO biological process
GO:0006096 glycolytic process
Ontology Mapping -
Source and Dest Ontology: MultiFun to GO
Mar 2004
GO cellular component
GO:0005737 cytoplasm
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR011193 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO molecular function
GO:0030170 pyridoxal phosphate binding
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR015422 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO molecular function
GO:0016831 carboxy-lyase activity
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR005308 Reference: Escherichia coli K-12 MG1655
Apr 2008
GO molecular function
GO:0003824 catalytic activity
GO Inferred from Electronic Annotation -
Database Name:Identifier: INTERPRO:IPR000310 Reference: Escherichia coli K-12 MG1655
Apr 2008
Comparative
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Experimental
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Context Table
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Listed below are features that lie nearby this feature.
Features encoded in multiple intervals may
appear more than once in the table. Features that span the origin
will have a left endpoint greater than the right endpoint.
Features overlapping the region 204679 to 216820
FeatureID Name Feature Type Strand Left End Right End Relationship ABE-0000001 source forward 1 4641652 Contains
ABE-0000622 rnhB CDS forward 204493 205089 Upstream
ABE-0000624 dnaE CDS forward 205126 208608 Upstream
ABE-0000630 accA CDS forward 208621 209580 Upstream
ABE-0000633 ldcC CDS forward 209679 211820 Matches
ABE-0000635 yaeR CDS forward 211877 212266 Downstream
ABE-0000638 tilS CDS forward 212331 213629 Downstream
ABE-0285334 repeat_region forward 213632 213668 Downstream
ABE-0000641 rof CDS complement 213678 213932 Downstream
ABE-0047214 yaeP CDS complement 213925 214125 Downstream
ABE-0000648 yaeQ CDS forward 214291 214836 Downstream
ABE-0000650 arfB CDS forward 214833 215255 Downstream
ABE-0000652 nlpE CDS forward 215269 215979 Downstream
ABE-0285335 repeat_region forward 216027 216137 Downstream
ABE-0000655 yaeF CDS complement 216179 217003 Downstream
Links download
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Release Notes
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All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.