Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001070 (betA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001070 showshow history
Names
betA JW0303 ECK0309 b0311
Product
choline dehydrogenase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome complement 325577 327247 1671 557
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR000172 (IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal) Apr 2008
Automated Process Approved IPR011533 (IPR011533 Oxygen-dependent choline dehydrogenase) Apr 2008
Automated Process Approved IPR012132 (IPR012132 Glucose-methanol-choline oxidoreductase) Apr 2008
Automated Process Approved IPR007867 (IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal) Apr 2008
Automated Process Approved IPR036188 (IPR036188 FAD/NAD(P)-binding domain superfamily) Jul 2018
Automated Process Approved PF05199 (PF05199 GMC oxidoreductase) Jul 2018
Automated Process Approved PF00732 (PF00732 GMC oxidoreductase) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Approved GO biological process GO:0006066 alcohol metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR012132
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0006578 amino-acid betaine biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0019285 glycine betaine biosynthetic process from choline GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011533
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR007867, IPR000172
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated GO biological process GO:0006970 response to osmotic stress Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0006118 (OBSOLETE) electron transport GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000172
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated GO cellular component GO:0019866 organelle inner membrane Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO molecular function GO:0008812 choline dehydrogenase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011533
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016614 oxidoreductase activity, acting on CH-OH group of donors GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000172
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0050660 flavin adenine dinucleotide binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000172
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name betA Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym ECK0309 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW0303 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b0311 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product choline dehydrogenase Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 		Oct 2021
Person Approved alternate product name choline dehydrogenase, a flavoprotein Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Protein Family
Automated Process Approved protein family IPR036188 FAD/NAD(P)-binding domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036188
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF05199 GMC oxidoreductase Protein Sequence Similarity - PFAM Model Name: PF05199
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF00732 GMC oxidoreductase Protein Sequence Similarity - PFAM Model Name: PF00732
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR011533 Oxygen-dependent choline dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR011533
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal Protein Sequence Similarity - InterPro Domain: IPR007867
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal Protein Sequence Similarity - InterPro Domain: IPR000172
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR012132 Glucose-methanol-choline oxidoreductase Protein Sequence Similarity - InterPro Domain: IPR012132
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Automated Process Uncurated EC number 1.1.-.- Published Annotation - Database Name: EC2GO: GO:0016614
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Approved EC number 1.1.99.1 Published Annotation - Swiss-Prot Accession Number: P17444 Feb 2006
Person Uncurated MultiFun 1.7.18 (metabolism; central intermediary metabolism; betaine biosynthesis) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 5.5.1 (cell processes; adaptation to stress; osmotic pressure) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 7.3 (location of gene products; inner membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 6.1 (cell structure; membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG10109 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0001070 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P17444 Published Annotation - Swiss-Prot Accession Number: P17444 Jan 2005
Automated Process Approved db xref GeneID:945716 Published Annotation - Entrez Gene Database ID: 945716
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:1786503 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P17444 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Osmotic adaptation Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006578 - betaine biosynthetic process; GO_process: GO:0006970 - response to osmotic stress Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC73414.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Approved GO biological process GO:0019285 glycine betaine biosynthetic process from choline GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011533
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0006066 alcohol metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR012132
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0006118 (OBSOLETE) electron transport GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000172
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0006970 response to osmotic stress Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0006578 amino-acid betaine biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR007867, IPR000172
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated GO cellular component GO:0019866 organelle inner membrane Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO molecular function GO:0050660 flavin adenine dinucleotide binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000172
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008812 choline dehydrogenase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011533
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016614 oxidoreductase activity, acting on CH-OH group of donors GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000172
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002919 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002926 betA CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002758 betA CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0002281 betA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002849 betA CDS
Ortholog
Automated Process Uncurated Go view Brenneria salicis ATCC 15712 [T] AMK-0000967 CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0001966 betA CDS
Automated Process Uncurated Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0001389 betA CDS
Person Uncurated Go view Dickeya dadantii 3937 ABF-0019708 betA CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0001622 betA CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC 49946 ACW-0301375 betA CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC BAA-2158 APN-0001879 betA CDS
Automated Process Uncurated Go view Erwinia tasmaniensis Et1/99 [T] AFI-0001841 betA CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0007457 betA CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0000390 CDS
Automated Process Uncurated Go view Escherichia coli APEC O1 (APEC) AEG-0000306 betA CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0003998 betA CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0009323 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007083 betA CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005800 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0076507 betA CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0000367 betA CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0000454 betA CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0007069 betA CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0008092 betA CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0000292 betA CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0004776 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0003868 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0010545 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0008128 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0009205 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007300 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4115 (EHEC) BAS-0005212 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007989 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0008944 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007835 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0009107 betA CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0007549 betA CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0007471 betA CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0008908 betA CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0024286 betA CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0008749 betA CDS
Automated Process Approved Go view Escherichia coli HS ADR-0005052 betA CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0000640 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0000335 betA CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0000315 betA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0000515 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0000595 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0000444 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0000429 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0000341 CDS
Automated Process Uncurated Go view Escherichia coli SMS-3-5 AFT-0000341 betA CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0130248 CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0004919 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0000341 betA CDS
Automated Process Uncurated Go view Ewingella americana ATCC 33852 [T] AMA-0000949 betA CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0000586 CDS
Automated Process Uncurated Go view Pantoea agglomerans IG1 APM-0001549 CDS
Automated Process Uncurated Go view Pantoea agglomerans SL1-M5 ALY-0003464 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0001512 betA CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0002558 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0002234 betA CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0001978 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0009485 CDS
Automated Process Uncurated Go view Pantoea sp. aB AJV-0001627 CDS
Automated Process Uncurated Go view Pantoea stewartii DC283 ACV-0285614 betA CDS
Automated Process Uncurated Go view Pantoea vagans C9-1 ALK-0005378 betA CDS
Person Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0062004 betA CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0001010 betA CDS
Person Uncurated Go view Pectobacterium carotovorum WPP14 ADT-0000437 betA CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0007555 CDS
Person Uncurated Go view Pseudomonas syringae pv. tomato DC3000 ADG-0000445 betA CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0004291 betA CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0000336 betA CDS
Person Uncurated Go view Xenorhabdus nematophila ATCC 19061 [T] ADW-0002175 betA CDS
Person Uncurated Go view Yersinia pestis 91001 (biovar Microtus) ACQ-0236573 betA CDS
Automated Process Uncurated Go view Yersinia pestis Antiqua (biovar Antiqua) BAE-0001303 betA CDS
Automated Process Uncurated Go view Yersinia pestis B42003004 (biovar Antiqua) BAL-0005230 betA CDS
Automated Process Uncurated Go view Yersinia pestis CA88-4125 (biovar Orientalis) BAF-0002202 betA CDS
Person Uncurated Go view Yersinia pestis CO92 (biovar Orientalis) ABY-0119070 betA CDS
Automated Process Uncurated Go view Yersinia pestis E1979001 (biovar Antiqua) BAM-0008070 betA CDS
Automated Process Uncurated Go view Yersinia pestis F1991016 (biovar Orientalis) BAQ-0004777 betA CDS
Automated Process Uncurated Go view Yersinia pestis FV-1 (biovar Orientalis) BAK-0001862 CDS
Automated Process Uncurated Go view Yersinia pestis K1973002 (biovar Mediaevalis) BAO-0005355 betA CDS
Automated Process Uncurated Go view Yersinia pestis Nepal516 (biovar Antiqua) BAD-0003411 betA CDS
Automated Process Uncurated Go view Yersinia pestis Pestoides F (biovar Pestoides) BAI-0003044 CDS
Automated Process Uncurated Go view Yersinia pestis UG05-0454 (biovar Antiqua) BAN-0006319 betA CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis IP31758 ADS-0006821 betA CDS
Person Uncurated Go view Yersinia pseudotuberculosis IP32953 ACZ-0001263 betA CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis PB1/+ AFV-0001505 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis YPIII AFW-0003467 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 320577 to 332247
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001054rclRCDSforward320227321081Downstream
ABE-0001058ykgECDSforward321608322327Downstream
ABE-0001060ykgFCDSforward322338323765Downstream
ABE-0001062ykgGCDSforward323758324453Downstream
ABE-0001066ykgHCDScomplement324696325364Downstream
ABE-0001070betACDScomplement325577327247Matches
ABE-0001072betBCDScomplement327261328733Upstream
ABE-0001076betICDScomplement328747329334Upstream
ABE-0001080betTCDSforward329463331496Upstream
ABE-0285783yahVCDSforward331802331876Upstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.