Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001113 (yahK) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001113 showshow history
Names
yahK JW0317 ECK0323 b0325
Product
NADPH-dependent aldehyde reductase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 342884 343933 1050 350
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR002328 (IPR002328 Alcohol dehydrogenase, zinc-type, conserved site) Apr 2008
Automated Process Approved IPR006140 (IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain) Apr 2008
Automated Process Approved IPR011032 (IPR011032 GroES-like superfamily) Apr 2008
Automated Process Approved IPR002085 (IPR002085 (DEPRECATED) Alcohol dehydrogenase superfamily, zinc-type) Apr 2008
Automated Process Approved IPR013154 (IPR013154 Alcohol dehydrogenase, N-terminal) Apr 2008
Automated Process Approved IPR013149 (IPR013149 Alcohol dehydrogenase, C-terminal) Apr 2008
Automated Process Approved IPR036291 (IPR036291 NAD(P)-binding domain superfamily) Jul 2018
Automated Process Approved IPR020843 (IPR020843 Polyketide synthase, enoylreductase domain) Jul 2018
Automated Process Approved PF00107 (PF00107 Zinc-binding dehydrogenase) Jul 2018
Automated Process Approved PF08240 (PF08240 Alcohol dehydrogenase GroES-like domain) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR013149, IPR013154
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0048037 (OBSOLETE) cofactor binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006140
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006140
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008270 zinc ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002328
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002328
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name yahK Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym ECK0323 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW0317 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b0325 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product NADPH-dependent aldehyde reductase Experimental - PubMed ID: 25108218
Reference: Escherichia coli K-12 BW25113 		Sep 2021
Person Approved alternate product name putative oxidoreductase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name predicted oxidoreductase, Zn-dependent and NAD(P)-binding Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 		Sep 2021
Person Uncurated alternate product name putative dehydrogenase, NAD(P)-binding Published Annotation - Database Name: GenProtEC Jan 2006
Protein Family
Automated Process Approved protein family IPR002328 Alcohol dehydrogenase, zinc-type, conserved site Protein Sequence Similarity - InterPro Domain: IPR002328
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain Protein Sequence Similarity - InterPro Domain: IPR006140
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR013154 Alcohol dehydrogenase, N-terminal Protein Sequence Similarity - InterPro Domain: IPR013154
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR002085 (DEPRECATED) Alcohol dehydrogenase superfamily, zinc-type Protein Sequence Similarity - InterPro Domain: IPR002085
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR013149 Alcohol dehydrogenase, C-terminal Protein Sequence Similarity - InterPro Domain: IPR013149
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR020843 Polyketide synthase, enoylreductase domain Protein Sequence Similarity - InterPro Domain: IPR020843
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR011032 GroES-like superfamily Protein Sequence Similarity - InterPro Domain: IPR011032
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF08240 Alcohol dehydrogenase GroES-like domain Protein Sequence Similarity - PFAM Model Name: PF08240
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR036291 NAD(P)-binding domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036291
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF00107 Zinc-binding dehydrogenase Protein Sequence Similarity - PFAM Model Name: PF00107
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Person Approved EC number 1.-.-.- Published Annotation - Swiss-Prot Accession Number: P75691 Feb 2006
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:944975 Published Annotation - Entrez Gene Database ID: 944975
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Person Approved db xref UniProtKB:P75691 Published Annotation - Swiss-Prot Accession Number: P75691 Jan 2005
Automated Process Approved db xref GI:1786518 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P75691 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0001113 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG13595 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function putative enzyme; Not classified Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note putative oxidoreductase Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC73428.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 9.97
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR013149, IPR013154
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0008270 zinc ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002328
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002328
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006140
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0048037 (OBSOLETE) cofactor binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006140
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002661 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0003295 yahK CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002707 yahK CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0002781 yahK CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002657 yahK CDS
Ortholog
Automated Process Uncurated Go view Dickeya chrysanthemi Ech1591 AFK-0008996 CDS
Person Uncurated Go view Dickeya dadantii 3937 ABF-0017021 yahK CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0001494 CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC 49946 ACW-0296981 CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC BAA-2158 APN-0003522 adhC CDS
Automated Process Uncurated Go view Erwinia tasmaniensis Et1/99 [T] AFI-0003192 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0007472 CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0000405 CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0000324 yahK CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0003978 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0009307 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007062 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005780 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0076521 yahK CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0000381 CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0000474 yahK CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0007049 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0008072 CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0004799 CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0003892 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0010568 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0008151 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0009228 CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007322 CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0005235 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007967 CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0008966 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007857 CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0009130 CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0007572 CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0007449 CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0008930 CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0024310 yahK CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0008735 yahK CDS
Automated Process Approved Go view Escherichia coli HS ADR-0005072 CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0000654 CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0000329 yahK CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0000494 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0000578 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0000489 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0000445 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0174538 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0000359 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0000355 CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0130270 yahK CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0004944 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0000360 yahK CDS
Automated Process Uncurated Go view Ewingella americana ATCC 33852 [T] AMA-0001206 CDS
Automated Process Uncurated Go view Pantoea agglomerans IG1 APM-0003386 CDS
Automated Process Uncurated Go view Pantoea agglomerans SL1-M5 ALY-0002350 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0003524 yahK CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0000463 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0000292 yahK CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0004092 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0008071 CDS
Automated Process Uncurated Go view Pantoea sp. aB AJV-0003798 CDS
Automated Process Uncurated Go view Pantoea stewartii DC283 ACV-0288851 yahK CDS
Automated Process Uncurated Go view Pantoea vagans C9-1 ALK-0007286 adhc3 CDS
Person Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0064267 CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0002275 CDS
Person Uncurated Go view Pectobacterium carotovorum WPP14 ADT-0001024 CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0008970 CDS
Person Uncurated Go view Pseudomonas syringae pv. tomato DC3000 ADG-0002744 CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0001396 CDS
Person Approved Go view Shigella sonnei 046 ADD-0000333 yahK CDS
Automated Process Uncurated Go view Yersinia bercovieri ATCC 43970 [T] AEK-0002596 CDS
Automated Process Uncurated Go view Yersinia enterocolitica 8081 BAH-0010687 CDS
Automated Process Uncurated Go view Yersinia frederiksenii ATCC 33641 [T] AEI-0004020 adhC2 CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0003965 adhC2 CDS
Automated Process Uncurated Go view Yersinia mollaretii ATCC 43969 [T] AEJ-0000256 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB20147mutantTn5 InsertionRequest the StrainABE-0001113yahKyahK::Tn5KAN-I-SceI at position 211 in Minus orientation ,+ pKD460Blattner Laboratory
FB20148mutantTn5 InsertionRequest the StrainABE-0001113yahKyahK::Tn5KAN-I-SceI at position 211 in Minus orientation ,- pKD465Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 337884 to 348933
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001099yahFCDSforward336778338325Upstream
ABE-0001101yahGCDSforward338325339743Upstream
ABE-0285346repeat_regionforward339757340114Upstream
ABE-0001107yahICDSforward340165341115Upstream
ABE-0001109yahJCDSforward341125342507Upstream
ABE-0285262pseudogeneforward342591342640Upstream
ABE-0285263pseudogeneforward342726342797Upstream
ABE-0001113yahKCDSforward342884343933Matches
ABE-0001117yahLCDSforward344176344991Downstream
ABE-0001120yahMCDSforward345404345649Downstream
ABE-0001122yahNCDScomplement345666346337Downstream
ABE-0001130yahOCDSforward346484346759Downstream
ABE-0285347repeat_regionforward346824346853Downstream
ABE-0001133prpRCDScomplement346857348443Downstream
ABE-0001138prpBCDSforward348682349572Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.