Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001201 (mhpC) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001201 showshow history
Names
mhpC JW0340 ECK0346 b0349
Product
2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 371239 372105 867 289

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Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR000639 (IPR000639 Epoxide hydrolase-like) Apr 2008
Automated Process Approved IPR003089 (IPR003089 (DEPRECATED) Alpha/beta hydrolase) Apr 2008
Automated Process Approved IPR000073 (IPR000073 Alpha/beta hydrolase fold-1) Apr 2008
Automated Process Approved IPR029058 (IPR029058 Alpha/Beta hydrolase fold) Jul 2018
Automated Process Approved PF12697 (PF12697 Alpha/beta hydrolase family) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Approved GO biological process GO:0006725 cellular aromatic compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003089
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0019395 fatty acid oxidation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0016787 hydrolase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003089
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000639
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name mhpC Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym JW0340 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ECK0346 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b0349 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Approved product 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved alternate product name 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name 2-hydroxy-6-ketonone-2,4-dienedioic acid hydrolase Published Annotation - Database Name: GenProtEC Jan 2006
Protein Family
Automated Process Approved protein family IPR000639 Epoxide hydrolase-like Protein Sequence Similarity - InterPro Domain: IPR000639
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR029058 Alpha/Beta hydrolase fold Protein Sequence Similarity - InterPro Domain: IPR029058
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR003089 (DEPRECATED) Alpha/beta hydrolase Protein Sequence Similarity - InterPro Domain: IPR003089
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF12697 Alpha/beta hydrolase family Protein Sequence Similarity - PFAM Model Name: PF12697
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR000073 Alpha/beta hydrolase fold-1 Protein Sequence Similarity - InterPro Domain: IPR000073
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Person Approved EC number 3.7.1.- Published Annotation - Swiss-Prot Accession Number: P77044 Feb 2006
Person Uncurated MultiFun 1.1.2 (metabolism; carbon utilization; fatty acids) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GI:452909625 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:944954 Published Annotation - Entrez Gene Database ID: 944954
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref ASAP:ABE-0001201 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P77044 Published Annotation - Swiss-Prot Accession Number: P77044 Jan 2005
Automated Process Approved db xref UniProtKB/Swiss-Prot:P77044 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG20275 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Degradation of small molecules: Carbon compounds Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note GO_process: GO:0019395 - fatty acid oxidation Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC73452.3 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Approved GO biological process GO:0006725 cellular aromatic compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003089
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0019395 fatty acid oxidation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0016787 hydrolase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003089
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000639
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0004046 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0004516 mhpC CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0004833 mhpC CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0007757 mhpC CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0003780 mhpC CDS
Ortholog
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0001634 mhpC CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0008204 mhpC CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0006166 mhpC CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0009282 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0010222 mhpC CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0009970 CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0000409 mhpC CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0000498 mhpC CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0008980 mhpC CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0004823 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0000377 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0010596 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0008178 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0010782 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007910 mhpC CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0005263 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0010473 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0008994 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007885 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0007713 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0007079 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0010315 mhpC CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0010751 mhpC CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0024339 mhpC CDS
Automated Process Approved Go view Escherichia coli HS ADR-0005095 mhpC CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0000353 mhpC CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0000352 mhpC CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0000603 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0000554 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0000465 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0000383 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0000379 mhpC CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0130295 mhpC CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0004970 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0002126 mhpC CDS
Person Uncurated Go view Shewanella oneidensis MR-1 ACY-0265309 CDS
Molecular Interactions to toptop
Author Approval Feature Name Technique Evidence Comment Annotated
Person Approved ABE-0001201 mhpC lambda repressor assay Doodle - bnumber: b0349 Oct 2003
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 366239 to 377105
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001183lacZCDScomplement363231366305Upstream
ABE-0001189lacICDScomplement366428367510Upstream
ABE-0001191mhpRCDScomplement367587368420Upstream
ABE-0001196mhpACDSforward368611370275Upstream
ABE-0001198mhpBCDSforward370277371221Upstream
ABE-0001201mhpCCDSforward371239372105Matches
ABE-0001205mhpDCDSforward372115372924Downstream
ABE-0001207mhpFCDSforward372921373871Downstream
ABE-0001209mhpECDSforward373868374881Downstream
ABE-0285354repeat_regionforward374930375365Downstream
ABE-0001213mhpTCDSforward375459376670Downstream
ABE-0001216yaiLCDSforward376772377311Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.