Escherichia coli K-12 MG1655
Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001205 (mhpD) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001205 showshow history
Names
mhpD JW0341 ECK0347 mhpS b0350
Product
2-keto-4-pentenoate hydratase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 372115 372924 810 270
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR002607 (IPR002607 (DEPRECATED) Hydratase/decarboxylase) Apr 2008
Automated Process Approved IPR011234 (IPR011234 Fumarylacetoacetase-like, C-terminal) Jul 2018
Automated Process Approved IPR036663 (IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily) Jul 2018
Automated Process Approved PF01557 (PF01557 Fumarylacetoacetate (FAA) hydrolase family) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0019395 fatty acid oxidation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011234, IPR036663
Reference: Escherichia coli K-12 MG1655
Jul 2018
Automated Process Approved GO biological process GO:0006725 cellular aromatic compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002607
Reference: Escherichia coli K-12 MG1655
Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655
Feb 2008
Automated Process Uncurated GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011234, IPR036663
Reference: Escherichia coli K-12 MG1655
Jul 2018
Automated Process Approved GO molecular function GO:0016829 lyase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002607
Reference: Escherichia coli K-12 MG1655
Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name mhpD Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Oct 1998
Person Approved synonym ECK0347 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW0341 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym mhpS Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved locus tag b0350 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Approved product 2-keto-4-pentenoate hydratase Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved alternate product name 2-keto-4-pentenoate hydratase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Jan 2006
Protein Family
Automated Process Approved protein family IPR002607 (DEPRECATED) Hydratase/decarboxylase Protein Sequence Similarity - InterPro Domain: IPR002607
Reference: Escherichia coli K-12 MG1655
Apr 2008
Automated Process Approved protein family PF01557 Fumarylacetoacetate (FAA) hydrolase family Protein Sequence Similarity - PFAM Model Name: PF01557
Reference: Escherichia coli K-12 MG1655
Jul 2018
Automated Process Approved protein family IPR011234 Fumarylacetoacetase-like, C-terminal Protein Sequence Similarity - InterPro Domain: IPR011234
Reference: Escherichia coli K-12 MG1655
Jul 2018
Automated Process Approved protein family IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036663
Reference: Escherichia coli K-12 MG1655
Jul 2018
Other
Person Approved EC number 4.2.1.- Published Annotation - Swiss-Prot Accession Number: P77608 Feb 2006
Person Uncurated MultiFun 1.1.2 (metabolism; carbon utilization; fatty acids) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved db xref EcoGene:EG14274 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved db xref ASAP:ABE-0001205 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Person Approved db xref UniProtKB:P77608 Published Annotation - Swiss-Prot Accession Number: P77608 Jan 2005
Automated Process Approved db xref GI:87081722 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved db xref GeneID:944768 Published Annotation - Entrez Gene Database ID: 944768
Reference: Escherichia coli K-12 MG1655
Jun 2009
Automated Process Approved db xref UniProtKB/Swiss-Prot:P77608 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Person Approved function enzyme; Degradation of small molecules: Carbon compounds Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Oct 1998
Automated Process Approved note GO_process: GO:0019395 - fatty acid oxidation Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved protein id AAC73453.2 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655
Feb 2008
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655
Mar 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655
Jan 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655
Feb 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Gene Ontology
Automated Process Approved GO biological process GO:0006725 cellular aromatic compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002607
Reference: Escherichia coli K-12 MG1655
Apr 2008
Person Uncurated GO biological process GO:0019395 fatty acid oxidation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011234, IPR036663
Reference: Escherichia coli K-12 MG1655
Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655
Feb 2008
Automated Process Uncurated GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011234, IPR036663
Reference: Escherichia coli K-12 MG1655
Jul 2018
Automated Process Approved GO molecular function GO:0016829 lyase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002607
Reference: Escherichia coli K-12 MG1655
Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0005367 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002315 mhpD CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002474 mhpD CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0006231 mhpD CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0003823 mhpD CDS
Ortholog
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0001635 mhpD CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0008203 mhpD CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0006165 mhpD CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0009281 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0010221 mhpD CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0009971 CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0000410 mhpD CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0000499 mhpD CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0008981 mhpD CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0004824 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0000378 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0010597 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0008179 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0010783 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007911 mhpD CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0005264 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0010472 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0008995 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007886 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0007714 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0007080 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0010316 mhpD CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0010752 mhpD CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0024340 mhpD CDS
Automated Process Approved Go view Escherichia coli HS ADR-0005096 mhpD CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0000353 mhpD CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0000602 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0000553 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0000464 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0000384 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0000380 mhpD CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0130296 mhpD CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0004971 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0002125 mhpD CDS
Person Uncurated Go view Shewanella oneidensis MR-1 ACY-0267685 CDS
Person Approved Go view Shigella sonnei 046 ADD-0000357 mhpD CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)

Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 367115 to 377924
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001189lacICDScomplement366428367510Upstream
ABE-0001191mhpRCDScomplement367587368420Upstream
ABE-0001196mhpACDSforward368611370275Upstream
ABE-0001198mhpBCDSforward370277371221Upstream
ABE-0001201mhpCCDSforward371239372105Upstream
ABE-0001205mhpDCDSforward372115372924Matches
ABE-0001207mhpFCDSforward372921373871Overlaps Downstream
ABE-0001209mhpECDSforward373868374881Downstream
ABE-0285354repeat_regionforward374930375365Downstream
ABE-0001213mhpTCDSforward375459376670Downstream
ABE-0001216yaiLCDSforward376772377311Downstream
ABE-0285355repeat_regionforward377335377521Downstream
ABE-0001219frmBCDScomplement377535378368Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.