Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001207 (mhpF) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001207 showshow history
Names
mhpF JW0342 ECK0348 b0351
Product
acetaldehyde dehydrogenase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 372921 373871 951 317
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR003361 (IPR003361 Acetaldehyde dehydrogenase) Apr 2008
Automated Process Approved IPR000534 (IPR000534 Semialdehyde dehydrogenase, NAD-binding) Apr 2008
Automated Process Approved IPR015426 (IPR015426 Acetaldehyde dehydrogenase, C-terminal) Apr 2008
Automated Process Approved IPR036291 (IPR036291 NAD(P)-binding domain superfamily) Jul 2018
Automated Process Approved PF01118 (PF01118 Semialdehyde dehydrogenase, NAD binding domain) Jul 2018
Automated Process Approved PF09290 (PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0019395 fatty acid oxidation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0019439 aromatic compound catabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015426, IPR003361
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000534, IPR015426, IPR003361
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO biological process GO:0006520 cellular amino acid metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO cellular component GO:0005737 cytoplasm Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO molecular function GO:0008774 acetaldehyde dehydrogenase (acetylating) activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015426, IPR003361
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0051287 NAD binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name mhpF Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym JW0342 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ECK0348 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b0351 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product acetaldehyde dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR003361
Reference: Escherichia coli K-12 MG1655 		Sep 2021
Person Uncurated alternate product name acetaldehyde-CoA dehydrogenase II, NAD-binding Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 		Sep 2021
Protein Family
Automated Process Approved protein family IPR000534 Semialdehyde dehydrogenase, NAD-binding Protein Sequence Similarity - InterPro Domain: IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF01118 Semialdehyde dehydrogenase, NAD binding domain Protein Sequence Similarity - PFAM Model Name: PF01118
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR015426 Acetaldehyde dehydrogenase, C-terminal Protein Sequence Similarity - InterPro Domain: IPR015426
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation Protein Sequence Similarity - PFAM Model Name: PF09290
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR036291 NAD(P)-binding domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036291
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR003361 Acetaldehyde dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR003361
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Person Approved EC number 1.2.1.10 Published Annotation - Swiss-Prot Accession Number: P77580 Feb 2006
Automated Process Uncurated EC number 1.2.1.- Published Annotation - Database Name: EC2GO: GO:0016620
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated MultiFun 1.1.2 (metabolism; carbon utilization; fatty acids) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 7.1 (location of gene products; cytoplasm) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0001207 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG13625 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:945008 Published Annotation - Entrez Gene Database ID: 945008
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:1786547 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P77580 Published Annotation - Swiss-Prot Accession Number: P77580 Jan 2005
Automated Process Approved db xref UniProtKB/Swiss-Prot:P77580 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Degradation of small molecules: Carbon compounds Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note acetaldehyde dehydrogenase; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0019395 - fatty acid oxidation Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC73454.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO biological process GO:0019439 aromatic compound catabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015426, IPR003361
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000534, IPR015426, IPR003361
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO biological process GO:0006520 cellular amino acid metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0019395 fatty acid oxidation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO cellular component GO:0005737 cytoplasm Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0051287 NAD binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO molecular function GO:0008774 acetaldehyde dehydrogenase (acetylating) activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015426, IPR003361
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000534
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0006527 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0004515 mhpF CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0004862 mhpF CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0006318 mhpF CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0003825 mhpF CDS
Ortholog
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0001636 mhpF CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0008202 mhpF CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0006164 mhpF CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0009280 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0010220 mhpF CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0009972 CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0000411 CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0000500 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0008982 mhpF CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0004825 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0000379 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0010598 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0008180 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0010784 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007912 mhpF CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0005265 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0010471 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0008996 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007887 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0007715 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0007081 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0010317 mhpF CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0010753 mhpF CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0024341 mhpF CDS
Automated Process Approved Go view Escherichia coli HS ADR-0005097 mhpF CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0000354 mhpF CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0000601 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0000552 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0000463 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0000385 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0000381 mhpF CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0130297 mhpF CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0004972 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0002124 mhpF CDS
Person Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0061684 nahO CDS
Person Approved Go view Shigella sonnei 046 ADD-0000358 mhpF CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 367921 to 378871
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001191mhpRCDScomplement367587368420Upstream
ABE-0001196mhpACDSforward368611370275Upstream
ABE-0001198mhpBCDSforward370277371221Upstream
ABE-0001201mhpCCDSforward371239372105Upstream
ABE-0001205mhpDCDSforward372115372924Overlaps Upstream
ABE-0001207mhpFCDSforward372921373871Matches
ABE-0001209mhpECDSforward373868374881Overlaps Downstream
ABE-0285354repeat_regionforward374930375365Downstream
ABE-0001213mhpTCDSforward375459376670Downstream
ABE-0001216yaiLCDSforward376772377311Downstream
ABE-0285355repeat_regionforward377335377521Downstream
ABE-0001219frmBCDScomplement377535378368Downstream
ABE-0001221frmACDScomplement378462379571Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.