Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001863 (emrE) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001863 showshow history
Names
emrE ECK0534 eb JW0531 rodY envB mon mvrC b0543
Product
DLP12 prophage; multidrug resistance protein
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 568315 568647 333 111
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR000390 (IPR000390 Small multidrug resistance protein family) Apr 2008
Automated Process Approved PF00893 (PF00893 Small Multidrug Resistance protein) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0042493 response to drug Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO cellular component GO:0016021 integral component of membrane GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000390
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005886 plasma membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name emrE Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym rodY Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved synonym ECK0534 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW0531 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym mvrC Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Automated Process Approved synonym eb Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved synonym mon Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved synonym envB Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved locus tag b0543 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Approved product DLP12 prophage; multidrug resistance protein Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved alternate product name methylviologen resistance Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name DLP12 prophage; auxillary multidrug transport protein, methylviologen and ethidium resistance (SMR family) Published Annotation - Database Name: GenProtEC Jan 2006
Protein Family
Automated Process Approved protein family IPR000390 Small multidrug resistance protein family Protein Sequence Similarity - InterPro Domain: IPR000390
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF00893 Small Multidrug Resistance protein Protein Sequence Similarity - PFAM Model Name: PF00893
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Person Uncurated MultiFun 6.1 (cell structure; membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 4.8.A.1 (transport; Group Translocators; Accessory Factors Involved in Transport; The Membrane Fusion Protein (MFP) Family) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 7.3 (location of gene products; inner membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 4.S.126 (transport; substrate; multidrug) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 8.1 (extrachromosomal; prophage genes and phage related functions) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 5.6.4 (cell processes; protection; drug resistance/sensitivity) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0001863 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:948442 Published Annotation - Entrez Gene Database ID: 948442
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:1786755 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P23895 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P23895 Published Annotation - Swiss-Prot Accession Number: P23895 Jan 2005
Automated Process Approved db xref EcoGene:EG10629 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved function transport; Drug/analog sensitivity; Phage or Prophage Related Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved note methylviologen resistance; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0042493 - response to drug Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC73644.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Membrane Predicted by PSORTb - PSORTb Final_Score: 10.00
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0042493 response to drug Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005886 plasma membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO cellular component GO:0016021 integral component of membrane GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000390
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Homolog
Person Uncurated Go view Escherichia coli CFT073 (UPEC) ABR-0078475 emrE CDS
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002627 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0001314 emrE CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0001260 emrE CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0001173 emrE CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002845 emrE CDS
Ortholog
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0002039 CDS
Automated Process Uncurated Go view Dickeya chrysanthemi Ech1591 AFK-0007922 CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0001200 CDS
Automated Process Uncurated Go view Erwinia tasmaniensis Et1/99 [T] AFI-0003513 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0004110 emrE CDS
Automated Process Uncurated Go view Escherichia coli ATCC 11775 [T] AMC-0002455 CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0005938 emrE CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0008141 emrE CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0007917 emrE CDS
Automated Process Uncurated Go view Escherichia coli F11 (UPEC) ADQ-0008477 emrE_1 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0000538 emrE CDS
Person Uncurated Go view Escherichia coli K-12 W3110 ADY-0000546 emrE CDS
Automated Process Uncurated Go view Musicola paradisiaca Ech703 AGA-0005661 CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0003164 CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0003189 CDS
Person Uncurated Go view Shewanella oneidensis MR-1 ACY-0268581 CDS
Person Uncurated Go view Wigglesworthia morsitans AEQ-0000115 emrE CDS
Automated Process Uncurated Go view Yersinia pestis Angola (biovar Pestoides) ADI-0006321 CDS
Automated Process Uncurated Go view Yersinia pestis B42003004 (biovar Antiqua) BAL-0004822 CDS
Automated Process Uncurated Go view Yersinia pestis E1979001 (biovar Antiqua) BAM-0007037 CDS
Automated Process Uncurated Go view Yersinia pestis F1991016 (biovar Orientalis) BAQ-0006681 CDS
Automated Process Uncurated Go view Yersinia pestis IP275 (biovar Orientalis) BAC-0007934 CDS
Automated Process Uncurated Go view Yersinia pestis MG05-1020 (biovar Orientalis) BAP-0008123 CDS
Automated Process Uncurated Go view Yersinia pestis UG05-0454 (biovar Antiqua) BAN-0007036 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis PB1/+ AFV-0002773 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis YPIII AFW-0002258 CDS
Molecular Interactions to toptop
Author Approval Feature Name Technique Evidence Comment Annotated
Person Approved ABE-0001863 emrE lambda repressor assay Doodle - bnumber: b0543 Oct 2003
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 563315 to 573647
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001832sfmHpseudogeneforward562313563319Upstream
ABE-0001834sfmFCDSforward563330563845Upstream
ABE-0001836fimZCDScomplement563848564480Upstream
ABE-0001840argUtRNAforward564723564799Upstream
ABE-0234206DLP12 (qsr')prophageforward564802586103Contains
ABE-0285377misc_featureforward564802586103Contains
ABE-0001842intDCDScomplement564815565978Upstream
ABE-0285157xisDpseudogenecomplement565855566073Upstream
ABE-0001850exoDpseudogenecomplement566098566376Upstream
ABE-0285029peaDpseudogeneforward566376566687Upstream
ABE-0001860renDpseudogeneforward566684566774(Interval #1) Upstream
ABE-0001853mobile_elementforward566777568034Upstream
ABE-0001855insE-3CDSforward566842567141Upstream
ABE-0001857insF-3CDSforward567138568004Upstream
ABE-0001860renDpseudogeneforward568036568247(Interval #2) Upstream
ABE-0001863emrECDSforward568315568647Matches
ABE-0285751ylcJCDSforward568695568844Downstream
ABE-0001866ybcKCDSforward568902570428Downstream
ABE-0001869ybcLCDSforward570893571444Downstream
ABE-0001871ybcMCDSforward571454572251Downstream
ABE-0285174ylcHCDSforward572368572469Downstream
ABE-0001874ybcNCDSforward572466572921Downstream
ABE-0001876ninECDSforward572921573091Downstream
ABE-0001878ybcOCDSforward573084573374Downstream
ABE-0001880rusACDSforward573371573733Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.