Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001958 (cusC) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001958 showshow history
Names
cusC ibeB silC JW0561 ECK0564 ylcB b0572
Product
copper/silver export system outer membrane channel
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 595600 596973 1374 458
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR010131 (IPR010131 RND efflux system, outer membrane lipoprotein, NodT) Apr 2008
Automated Process Approved IPR003423 (IPR003423 Outer membrane efflux protein) Apr 2008
Automated Process Approved PF02321 (PF02321 Outer membrane efflux protein) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Approved GO biological process GO:0006810 transport GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO biological process GO:0055085 transmembrane transport GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR003423, IPR010131
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0009279 cell outer membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO cellular component GO:0016020 membrane GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO cellular component GO:0009279 cell outer membrane Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO molecular function GO:0022857 transmembrane transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010131
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO molecular function GO:0015562 efflux transmembrane transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR003423
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0008289 lipid binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0005215 transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name cusC Experimental - PubMed ID: 11004187
Reference: Escherichia coli 		Aug 2002
Person Approved synonym ECK0564 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW0561 Published Annotation - PubMed ID: 16397293 Jan 2006
Automated Process Approved synonym ibeB Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved synonym silC Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved synonym ylcB Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved locus tag b0572 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product copper/silver export system outer membrane channel Published Annotation - EcoCyc Accession Number: G6320
Reference: Escherichia coli K-12 MG1655 		Oct 2021
Person Approved alternate product name copper/silver efflux system, outer membrane component Published Annotation - PubMed ID: 16397293 Jan 2006
Person Uncurated alternate product name outer membrane transport protein involved in copper (silver) tolerance Published Annotation - Database Name: GenProtEC Jan 2006
Person Uncurated alternate product name putative outer membrane protein involved in copper transport Experimental - PubMed ID: 11004187
Reference: Escherichia coli 		Jan 2006
Protein Family
Automated Process Approved protein family PF02321 Outer membrane efflux protein Protein Sequence Similarity - PFAM Model Name: PF02321
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR003423 Outer membrane efflux protein Protein Sequence Similarity - InterPro Domain: IPR003423
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR010131 RND efflux system, outer membrane lipoprotein, NodT Protein Sequence Similarity - InterPro Domain: IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Person Uncurated MultiFun 7.4 (location of gene products; outer membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 6.1 (cell structure; membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Uncurated comment A single nucleotide substitution at g.596196 (within codon 458) relative to Escherichia coli Sakai (EHEC) (ASAP:ACA-0130504) results in a termination codon, truncating the C-terminus by three amino acids; a comparison among orthologs shows that this difference coincides with the presence of an additional 125 nucleotides between the cusC and cusF features (annotated as IRU5 in EcoGene). Unpublished Sequence Analysis - Author Name, Email; Comment: Eric Neeno-Eckwall, ecneenoeckwa@wisc.edu
Reference: Escherichia coli K-12 MG1655 		Apr 2009
Automated Process Approved db xref GI:1786785 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0001958 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG14233 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:946288 Published Annotation - Entrez Gene Database ID: 946288
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref UniProtKB/Swiss-Prot:P77211 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P77211 Published Annotation - Swiss-Prot Accession Number: P77211 Jan 2005
Person Approved function putative transport; Drug/analog sensitivity Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0009279 - cell outer membrane Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC73673.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Outer Membrane Predicted by PSORTb - PSORTb Final_Score: 10.00
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Approved GO biological process GO:0006810 transport GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO biological process GO:0055085 transmembrane transport GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR003423, IPR010131
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0009279 cell outer membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated GO cellular component GO:0009279 cell outer membrane Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO cellular component GO:0016020 membrane GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008289 lipid binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO molecular function GO:0015562 efflux transmembrane transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR003423
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO molecular function GO:0022857 transmembrane transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010131
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0005215 transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010131
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002618 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0000115 cusC CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0001241 cusC CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0002289 cusC CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002109 cusC CDS
Ortholog
Automated Process Uncurated Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0001361 cusC_1 CDS
Automated Process Uncurated Go view Dickeya chrysanthemi Ech1591 AFK-0006128 CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0002782 CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0005210 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0001287 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0006522 cusC CDS
Automated Process Uncurated Go view Escherichia coli 536 (UPEC) AEF-0000607 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0005958 cusC CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0003776 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0009036 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007561 cusC CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0076734 cusC CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0000721 ttgC CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0007440 cusC CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0007062 cusC CDS
Automated Process Uncurated Go view Escherichia coli E2348/69 (EPEC) BCI-0000496 cusC CDS
Automated Process Uncurated Go view Escherichia coli E24377A (ETEC) ADO-0005037 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0001656 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0010827 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0008407 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0005669 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0005941 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4115 (EHEC) BAS-0005493 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007270 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0009226 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0006617 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0009594 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0005881 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0005877 cusC CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0006716 cusC CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0024557 cusC CDS
Automated Process Uncurated Go view Escherichia coli F11 (UPEC) ADQ-0007374 cusC_1 CDS
Automated Process Approved Go view Escherichia coli HS ADR-0005300 cusC CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0000567 cusC CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0000577 cusC CDS
Automated Process Uncurated Go view Escherichia coli SE11 AFS-0000646 CDS
Automated Process Uncurated Go view Escherichia coli SMS-3-5 AFT-0000589 cusC CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0130504 CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0005249 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0000574 cusC CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0004411 CDS
Automated Process Uncurated Go view Musicola paradisiaca Ech703 AGA-0007351 CDS
Automated Process Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0063754 oprJ CDS
Person Uncurated Go view Pseudomonas syringae pv. tomato DC3000 ADG-0004379 CDS
Person Uncurated Go view Shewanella oneidensis MR-1 ACY-0264377 CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0005068 cusC CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0071458 ylcB CDS
Person Approved Go view Shigella flexneri 301 ABT-0086830 ylcB CDS
Person Approved Go view Shigella sonnei 046 ADD-0000566 ylcB CDS
Automated Process Uncurated Go view Yersinia enterocolitica 8081 BAH-0001416 ibeB CDS
Automated Process Uncurated Go view Yersinia pestis 91001 (biovar Microtus) ACQ-0235570 ibeB CDS
Automated Process Uncurated Go view Yersinia pestis Angola (biovar Pestoides) ADI-0008134 oprM CDS
Automated Process Uncurated Go view Yersinia pestis Antiqua (biovar Antiqua) BAE-0003570 ibeB CDS
Automated Process Uncurated Go view Yersinia pestis B42003004 (biovar Antiqua) BAL-0008385 oprM CDS
Automated Process Uncurated Go view Yersinia pestis CA88-4125 (biovar Orientalis) BAF-0004279 ibeB CDS
Automated Process Uncurated Go view Yersinia pestis CO92 (biovar Orientalis) ABY-0127041 ibeB CDS
Automated Process Uncurated Go view Yersinia pestis E1979001 (biovar Antiqua) BAM-0006314 oprM CDS
Automated Process Uncurated Go view Yersinia pestis F1991016 (biovar Orientalis) BAQ-0005801 oprM CDS
Automated Process Uncurated Go view Yersinia pestis FV-1 (biovar Orientalis) BAK-0002384 CDS
Automated Process Uncurated Go view Yersinia pestis IP275 (biovar Orientalis) BAC-0005789 oprM CDS
Automated Process Uncurated Go view Yersinia pestis K1973002 (biovar Mediaevalis) BAO-0004141 oprM CDS
Automated Process Uncurated Go view Yersinia pestis MG05-1020 (biovar Orientalis) BAP-0006544 oprM CDS
Automated Process Uncurated Go view Yersinia pestis Nepal516 (biovar Antiqua) BAD-0000750 ibeB CDS
Automated Process Uncurated Go view Yersinia pestis Pestoides F (biovar Pestoides) BAI-0003937 CDS
Automated Process Uncurated Go view Yersinia pestis UG05-0454 (biovar Antiqua) BAN-0004967 oprM CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis IP31758 ADS-0007603 oprM CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis IP32953 ACZ-0000531 ibeB CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis PB1/+ AFV-0000618 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis YPIII AFW-0004409 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0004394 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0001204 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 590600 to 601973
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001939nfrACDScomplement587982590954Upstream
ABE-0001942nfrBCDScomplement590941593178Upstream
ABE-0001946cusSCDScomplement593328594770Upstream
ABE-0001948cusRCDScomplement594760595443Upstream
ABE-0001958cusCCDSforward595600596973Matches
ABE-0001967cusFCDSforward597131597463Downstream
ABE-0001969cusBCDSforward597479598702Downstream
ABE-0001971cusACDSforward598714601857Downstream
ABE-0001976phePCDSforward601959603335Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.