Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0001969 (cusB) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0001969 showshow history
Names
cusB silB JW0563 ECK0566 ylcD b0574
Product
copper/silver export system membrane fusion protein
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 597479 598702 1224 408
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR006143 (IPR006143 RND efflux pump, membrane fusion protein) Apr 2008
Automated Process Approved IPR032317 (IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain) Jul 2018
Automated Process Approved PF00529 (PF00529 Cation efflux system protein CusB domain 1) Jul 2018
Automated Process Approved PF16576 (PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0042493 response to drug Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0055085 transmembrane transport GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR006143
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO biological process GO:0009306 protein secretion GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006143
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO cellular component GO:0016020 membrane GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006143
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO molecular function GO:0005215 transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR006143
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0008565 (OBSOLETE) protein transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006143
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name cusB Published Annotation - Swiss-Prot Accession Number: P77239 Aug 2002
Person Approved synonym ylcD Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved synonym silB Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved synonym JW0563 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ECK0566 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b0574 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product copper/silver export system membrane fusion protein Published Annotation - EcoCyc Accession Number: G6322
Reference: Escherichia coli K-12 MG1655 		Oct 2021
Person Uncurated alternate product name possible component of copper transport system Published Annotation - Swiss-Prot Accession Number: P77239 Jan 2006
Person Uncurated alternate product name outer membrane transport protein involved in copper (silver) tolerance Published Annotation - Database Name: GenProtEC Jan 2006
Person Approved alternate product name copper/silver efflux system, membrane fusion protein Published Annotation - PubMed ID: 16397293 Jan 2006
Protein Family
Automated Process Approved protein family IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Protein Sequence Similarity - InterPro Domain: IPR032317
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion Protein Sequence Similarity - PFAM Model Name: PF16576
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF00529 Cation efflux system protein CusB domain 1 Protein Sequence Similarity - PFAM Model Name: PF00529
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR006143 RND efflux pump, membrane fusion protein Protein Sequence Similarity - InterPro Domain: IPR006143
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Person Uncurated MultiFun 4.9.B (transport; Transporters of Unknown Classification; Putative uncharacterized transport protein) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 5.6.4 (cell processes; protection; drug resistance/sensitivity) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG14235 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0001969 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GI:1786787 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:945189 Published Annotation - Entrez Gene Database ID: 945189
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref UniProtKB/Swiss-Prot:P77239 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P77239 Published Annotation - Swiss-Prot Accession Number: P77239 Jan 2005
Person Approved function putative transport; Drug/analog sensitivity Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note GO_process: GO:0042493 - response to drug Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC73675.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Unknown Predicted by PSORTb - PSORTb Final_Score: 2.50
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0042493 response to drug Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0009306 protein secretion GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006143
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO biological process GO:0055085 transmembrane transport GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR006143
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO cellular component GO:0016020 membrane GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006143
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008565 (OBSOLETE) protein transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006143
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO molecular function GO:0005215 transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR006143
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002224 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002996 cusB CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002728 cusB CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0004055 cusB CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002635 cusB CDS
Ortholog
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0001363 cusB_1 CDS
Automated Process Uncurated Go view Dickeya chrysanthemi Ech1591 AFK-0007852 CDS
Person Uncurated Go view Dickeya dadantii 3937 ABF-0020554 cusB CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0001263 CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0002744 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0001285 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0006520 cusB CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0000609 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0005956 cusB CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0000512 cusB CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0003774 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0009032 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007559 cusB CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0009890 CusB CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0076736 cusB CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0000617 cusB CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0000723 CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0007442 cusB CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0007060 cusB CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0000498 cusB CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0005039 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0001658 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0010829 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0008409 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0005671 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0005939 cusB CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0005495 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007272 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0009228 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0006619 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0009596 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0005879 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0005879 cusB CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0006718 cusB CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0024559 cusB CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0007376 cusB CDS
Automated Process Approved Go view Escherichia coli HS ADR-0005302 cusB CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0000869 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0000569 cusB CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0000579 cusB CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0000936 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0000856 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0000715 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0000654 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0174751 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0000648 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0000591 cusB CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0130506 cusB CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0005251 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0000576 CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0004409 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0004787 CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0004585 CDS
Automated Process Uncurated Go view Musicola paradisiaca Ech703 AGA-0005732 CDS
Automated Process Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0061638 cusB CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0000786 cusB CDS
Automated Process Uncurated Go view Pectobacterium carotovorum WPP14 ADT-0002674 cusB CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0004118 cusB CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0005971 CDS
Person Uncurated Go view Shewanella oneidensis MR-1 ACY-0268257 CDS
Person Uncurated Go view Shigella boydii 227 ADV-0000473 ylcD CDS
Automated Process Uncurated Go view Shigella boydii BS512 ADJ-0005865 cusB CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0005070 cusB CDS
Person Uncurated Go view Shigella flexneri 2457T ABQ-0071460 cusB pseudogene
Person Approved Go view Shigella sonnei 046 ADD-0000568 cusB CDS
Automated Process Uncurated Go view Yersinia bercovieri ATCC 43970 [T] AEK-0000310 CDS
Automated Process Uncurated Go view Yersinia enterocolitica 8081 BAH-0010415 CDS
Automated Process Uncurated Go view Yersinia frederiksenii ATCC 33641 [T] AEI-0002009 cusB CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0001873 cusB CDS
Automated Process Uncurated Go view Yersinia mollaretii ATCC 43969 [T] AEJ-0001415 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0004389 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0001206 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 592479 to 603702
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0001942nfrBCDScomplement590941593178Upstream
ABE-0001946cusSCDScomplement593328594770Upstream
ABE-0001948cusRCDScomplement594760595443Upstream
ABE-0001958cusCCDSforward595600596973Upstream
ABE-0001967cusFCDSforward597131597463Upstream
ABE-0001969cusBCDSforward597479598702Matches
ABE-0001971cusACDSforward598714601857Downstream
ABE-0001976phePCDSforward601959603335Downstream
ABE-0001978ybdGCDScomplement603416604663Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.