Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0004639 (tynA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0004639 showshow history
Names
tynA JW1381 ECK1383 maoA feaA b1386
Product
copper-containing amine oxidase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome complement 1449076 1451349 2274 758
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR012854 (IPR012854 Copper amine oxidase-like, N-terminal) Apr 2008
Automated Process Approved IPR015801 (IPR015801 (DEPRECATED) Copper amine oxidase, N2/N3-terminal) Apr 2008
Automated Process Approved IPR015802 (IPR015802 Copper amine oxidase, N3-terminal) Apr 2008
Automated Process Approved IPR015798 (IPR015798 Copper amine oxidase, catalytic domain) Apr 2008
Automated Process Approved IPR000269 (IPR000269 Copper amine oxidase) Apr 2008
Automated Process Approved IPR015800 (IPR015800 Copper amine oxidase, N2-terminal) Apr 2008
Automated Process Approved IPR016182 (IPR016182 Copper amine oxidase, N-terminal) Jul 2018
Automated Process Approved IPR036460 (IPR036460 Copper amine oxidase, catalytic domain superfamily) Jul 2018
Automated Process Approved IPR036582 (IPR036582 Copper amine oxidase-like, N-terminal domain superfamily) Jul 2018
Automated Process Approved PF02727 (PF02727 Copper amine oxidase, N2 domain) Jul 2018
Automated Process Approved PF02728 (PF02728 Copper amine oxidase, N3 domain) Jul 2018
Automated Process Approved PF07833 (PF07833 Copper amine oxidase N-terminal domain) Jul 2018
Automated Process Approved PF01179 (PF01179 Copper amine oxidase, enzyme domain) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0009063 cellular amino acid catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0009308 amine metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated GO biological process GO:0009310 amine catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0030288 outer membrane-bounded periplasmic space GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated GO cellular component GO:0042597 periplasmic space Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO molecular function GO:0048038 quinone binding GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO molecular function GO:0008131 primary amine oxidase activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0005507 copper ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000269
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name tynA Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym feaA Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved synonym JW1381 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym maoA Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved synonym ECK1383 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b1386 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product copper-containing amine oxidase Published Annotation - EcoCyc Accession Number: EG13139
Reference: Escherichia coli K-12 MG1655 		Oct 2021
Person Approved alternate product name copper amine oxidase (tyramine oxidase) Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Approved alternate product name tyramine oxidase, copper-requiring Published Annotation - PubMed ID: 16397293 Jan 2006
Protein Family
Automated Process Approved protein family IPR015798 Copper amine oxidase, catalytic domain Protein Sequence Similarity - InterPro Domain: IPR015798
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR015802 Copper amine oxidase, N3-terminal Protein Sequence Similarity - InterPro Domain: IPR015802
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR015801 (DEPRECATED) Copper amine oxidase, N2/N3-terminal Protein Sequence Similarity - InterPro Domain: IPR015801
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR012854 Copper amine oxidase-like, N-terminal Protein Sequence Similarity - InterPro Domain: IPR012854
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR036460 Copper amine oxidase, catalytic domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR000269 Copper amine oxidase Protein Sequence Similarity - InterPro Domain: IPR000269
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF02727 Copper amine oxidase, N2 domain Protein Sequence Similarity - PFAM Model Name: PF02727
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR015800 Copper amine oxidase, N2-terminal Protein Sequence Similarity - InterPro Domain: IPR015800
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR016182 Copper amine oxidase, N-terminal Protein Sequence Similarity - InterPro Domain: IPR016182
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR036582 Copper amine oxidase-like, N-terminal domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036582
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF02728 Copper amine oxidase, N3 domain Protein Sequence Similarity - PFAM Model Name: PF02728
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF01179 Copper amine oxidase, enzyme domain Protein Sequence Similarity - PFAM Model Name: PF01179
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF07833 Copper amine oxidase N-terminal domain Protein Sequence Similarity - PFAM Model Name: PF07833
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Automated Process Approved EC number 1.4.3.21 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Uncurated MultiFun 7.2 (location of gene products; periplasmic space) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.7.30 (metabolism; central intermediary metabolism; threonine catabolism) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.1.4 (metabolism; carbon utilization; amines) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.1.3 (metabolism; carbon utilization; amino acids) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0004639 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GI:1787651 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P46883 Published Annotation - Swiss-Prot Accession Number: P46883 Jan 2005
Automated Process Approved db xref EcoGene:EG13140 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:945939 Published Annotation - Entrez Gene Database ID: 945939
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref UniProtKB/Swiss-Prot:P46883 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Degradation of small molecules: Amines Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note copper amine oxidase (tyramine oxidase); GO_component: GO:0042597 - periplasmic space; GO_process: GO:0009063 - cellular amino acid catabolic process; GO_process: GO:0009310 - amine catabolic process Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC74468.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Periplasmic Predicted by PSORTb - PSORTb Final_Score: 10.00
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO biological process GO:0009308 amine metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated GO biological process GO:0009310 amine catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009063 cellular amino acid catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO cellular component GO:0042597 periplasmic space Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0030288 outer membrane-bounded periplasmic space GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO molecular function GO:0048038 quinone binding GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO molecular function GO:0008131 primary amine oxidase activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015800, IPR015802, IPR015798, IPR000269, IPR016182, IPR036460
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0005507 copper ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000269
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0005556 tynA CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0005425 tynA CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0008386 tynA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0004278 tynA CDS
Ortholog
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0002138 maoA CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0001805 CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0002554 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0008038 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0005282 tynA CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005172 tynA pseudogene
Person Uncurated Go view Escherichia coli BL21(DE3) AHL-0002476 pseudogene
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0001501 tynA CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0001820 maoA CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0005355 tynA CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0006239 tynA CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0006011 tynA CDS
Automated Process Approved Go view Escherichia coli HS ADR-0006151 tynA CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0001298 tynA CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0001421 tynA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0001390 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0001688 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0001587 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0001500 CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0000203 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0001471 tynA CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0000181 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0013065 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0003972 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB20303mutantTn5 InsertionRequest the StrainABE-0004639tynAtynA::Tn5KAN-2 at position 1459 in Minus orientation ,- pKD460Blattner Laboratory
FB20304mutantTn5 InsertionRequest the StrainABE-0004639tynAtynA::Tn5KAN-2 at position 1459 in Minus orientation ,+ pKD460Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 1444076 to 1456349
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0004623ydbHCDSforward14430511445690Downstream
ABE-0004625ynbECDSforward14456871445872Downstream
ABE-0004627ydbLCDSforward14458801446206Downstream
ABE-0004630feaRCDScomplement14463781447283Downstream
ABE-0004637feaBCDSforward14475191449018Downstream
ABE-0004639tynACDScomplement14490761451349Matches
ABE-0285719matS7protein_bindforward14515311451543Upstream
ABE-0004644paaZCDScomplement14515971453642Upstream
ABE-0004649paaACDSforward14539271454856Upstream
ABE-0004651paaBCDSforward14548681455155Upstream
ABE-0004653paaCCDSforward14551641455910Upstream
ABE-0004655paaDCDSforward14559251456422Upstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.