Escherichia coli K-12 MG1655
About ASAP Data Release Policy University of Wisconsin—Madison
Home    Overview    Annotations    BLAST    Downloads    Comparative Genomics    Experiments    Strains    Help (this script)    User: guest  / Log On   
Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0004725 (aldA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0004725 showshow history
Names
aldA JW1412 ECK1408 ald b1415
Product
aldehyde dehydrogenase A
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 1488232 1489671 1440 480
Sequence

Get full DNA or protein sequence

View sequence with flanking regions: bases upstream and bases downstream

Context

Browse sequence in GaPP

You last hovered over feature (none)
Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR012303 (IPR012303 (DEPRECATED) NAD-dependent aldehyde dehydrogenase) Apr 2008
Automated Process Approved IPR015590 (IPR015590 Aldehyde dehydrogenase domain) Apr 2008
Automated Process Approved IPR016161 (IPR016161 Aldehyde/histidinol dehydrogenase) Jul 2018
Automated Process Approved PF00171 (PF00171 Aldehyde dehydrogenase family) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Uncurated GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated GO biological process GO:0016052 carbohydrate catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009441 glycolate metabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0006113 fermentation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009438 methylglyoxal metabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name aldA Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym ald Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved synonym ECK1408 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW1412 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b1415 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product aldehyde dehydrogenase A Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 		Oct 2021
Person Approved alternate product name aldehyde dehydrogenase, NAD-linked Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name aldehyde dehydrogenase A, NAD-linked Published Annotation - Database Name: GenProtEC Jan 2006
Protein Family
Automated Process Approved protein family PF00171 Aldehyde dehydrogenase family Protein Sequence Similarity - PFAM Model Name: PF00171
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR016161 Aldehyde/histidinol dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR015590 Aldehyde dehydrogenase domain Protein Sequence Similarity - InterPro Domain: IPR015590
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR012303 (DEPRECATED) NAD-dependent aldehyde dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR012303
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Automated Process Uncurated EC number 1.-.-.- Published Annotation - Database Name: EC2GO: GO:0016491
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Approved EC number 1.2.1.22 Published Annotation - Swiss-Prot Accession Number: P25553 Feb 2006
Person Approved EC number 1.2.1.21 Published Annotation - Swiss-Prot Accession Number: P25553 Feb 2006
Person Uncurated MultiFun 1.7.25 (metabolism; central intermediary metabolism; glycolate metabolism) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.1.1 (metabolism; carbon utilization; carbon compounds) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.7.23 (metabolism; central intermediary metabolism; methylglyoxal metabolism) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.3.5 (metabolism; energy metabolism, carbon; fermentation) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P25553 Published Annotation - Swiss-Prot Accession Number: P25553 Jan 2005
Automated Process Approved db xref GeneID:945672 Published Annotation - Entrez Gene Database ID: 945672
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:1787684 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P25553 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0004725 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG10035 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Energy metabolism, carbon: Fermentation Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note aldehyde dehydrogenase, NAD-linked; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0009438 - methylglyoxal metabolic process; GO_process: GO:0006113 - fermentation; GO_process: GO:0009441 - glycolate metabolic process Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC74497.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 9.97
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0009441 glycolate metabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0006113 fermentation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009438 methylglyoxal metabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated GO biological process GO:0016052 carbohydrate catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Comparative to toptop
Author Approval Details Genome Feature Name Type
Homolog
Person Approved Go view Pectobacterium atrosepticum SCRI1043 ABL-0060319 aldA CDS
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0003765 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0003556 aldA CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0003370 aldA CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0006742 aldA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0003179 aldA CDS
Ortholog
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0002029 aldA CDS
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0002354 aldA CDS
Automated Process Uncurated Go view Citrobacter freundii ATCC 8090 [T] AVI-0003024 aldA CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0005416 aldA CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0001432 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0009999 CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0001403 aldA CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0002925 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0008009 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005147 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0077959 aldA CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0001526 aldA CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0001845 ald' CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0005330 aldA CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0006266 aldA CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0001658 aldA CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0006036 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0001015 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0005400 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0009765 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0009429 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007119 aldA CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0006861 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0009761 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0011336 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0008006 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0008890 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0008667 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0007413 aldA CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0008610 aldA CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0026078 aldA CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0006038 aldA CDS
Automated Process Approved Go view Escherichia coli HS ADR-0006176 aldA CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0001886 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0001326 aldA CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0001451 aldA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0001366 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0001711 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0001560 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0001650 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0175790 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0001527 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0001756 aldA CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0131989 aldA CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0002108 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0001644 aldA CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0001505 aldA CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0000145 CDS
Automated Process Uncurated Go view Pantoea agglomerans IG1 APM-0001329 CDS
Automated Process Uncurated Go view Pantoea agglomerans SL1-M5 ALY-0003714 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0001773 aldA CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0002513 aldA CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0001633 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0009747 CDS
Automated Process Uncurated Go view Pantoea sp. aB AJV-0001833 CDS
Automated Process Uncurated Go view Pantoea vagans C9-1 ALK-0005166 aldA CDS
Automated Process Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0060319 aldA CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0000059 aldA CDS
Person Uncurated Go view Pectobacterium carotovorum WPP14 ADT-0001247 aldA CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0000229 aldA CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0009440 CDS
Person Uncurated Go view Shigella boydii 227 ADV-0001852 aldA CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0007044 aldA CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0072545 aldA CDS
Person Approved Go view Shigella flexneri 301 ABT-0088095 aldA CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0001917 aldA CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB20313mutantTn5 InsertionRequest the StrainABE-0004725aldAaldA::Tn5KAN-2 at position 297 in Minus orientation ,+ pKD460Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 1483232 to 1494671
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0004718hrpACDSforward14830611486963Upstream
ABE-0004722ydcFCDSforward14872351488035Upstream
ABE-0004725aldACDSforward14882321489671Matches
ABE-0285449repeat_regionforward14896831489704Downstream
ABE-0004727gapC_2CDSpcomplement14897131489964Downstream
ABE-0285094gapCpseudogenecomplement14897131490713Downstream
ABE-0004733cybBCDSforward14909021491432Downstream
ABE-0285181rydCncRNAcomplement14914431491506Downstream
ABE-0004736ydcACDSforward14916771491850Downstream
ABE-0285741yncPCDSforward14918761491944Downstream
ABE-0047283hokBCDScomplement14919221492071Downstream
ABE-0004738mokBCDScomplement14919621492129Downstream
ABE-0047249sokBncRNAforward14921191492174Downstream
ABE-0004744trgCDSforward14924701494110Downstream
ABE-0004746ydcICDScomplement14941481495071Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.