Escherichia coli K-12 MG1655
About ASAP Data Release Policy University of Wisconsin—Madison
Home    Overview    Annotations    BLAST    Downloads    Comparative Genomics    Experiments    Strains    Help (this script)    User: guest  / Log On   
Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0004834 (curA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0004834 showshow history
Names
curA JW5907 ECK1443 yncB b1449
Product
NADPH-dependent curcumin/dihydrocurcumin reductase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 1519027 1520064 1038 346
Sequence

Get full DNA or protein sequence

View sequence with flanking regions: bases upstream and bases downstream

Context

Browse sequence in GaPP

You last hovered over feature (none)
Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR013149 (IPR013149 Alcohol dehydrogenase, C-terminal) Apr 2008
Automated Process Approved IPR002085 (IPR002085 (DEPRECATED) Alcohol dehydrogenase superfamily, zinc-type) Apr 2008
Automated Process Approved IPR011032 (IPR011032 GroES-like superfamily) Apr 2008
Automated Process Approved IPR036291 (IPR036291 NAD(P)-binding domain superfamily) Jul 2018
Automated Process Approved IPR020843 (IPR020843 Polyketide synthase, enoylreductase domain) Jul 2018
Automated Process Approved PF16884 (PF16884 N-terminal domain of oxidoreductase) Jul 2018
Automated Process Approved PF00107 (PF00107 Zinc-binding dehydrogenase) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR013149
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002085
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008270 zinc ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002085
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Uncurated name curA Published Annotation - PubMed ID: 21467222
Reference: Escherichia coli K-12 DH10B 		Feb 2021
Person Approved synonym yncB Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym JW5907 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ECK1443 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b1449 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product NADPH-dependent curcumin/dihydrocurcumin reductase Experimental - PubMed ID: 21467222
Reference: Escherichia coli K-12 DH10B 		Feb 2021
Person Approved alternate product name putative oxidoreductase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name predicted oxidoreductase, Zn-dependent and NAD(P)-binding Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 		Feb 2021
Person Uncurated alternate product name putative dehydrogenase, NAD(P)-binding Published Annotation - Database Name: GenProtEC Jan 2006
Automated Process Approved alternate product name curcumin/dihydrocurcumin reductase, NADPH-dependent Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Protein Family
Automated Process Approved protein family IPR036291 NAD(P)-binding domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036291
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR011032 GroES-like superfamily Protein Sequence Similarity - InterPro Domain: IPR011032
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF16884 N-terminal domain of oxidoreductase Protein Sequence Similarity - PFAM Model Name: PF16884
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF00107 Zinc-binding dehydrogenase Protein Sequence Similarity - PFAM Model Name: PF00107
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR002085 (DEPRECATED) Alcohol dehydrogenase superfamily, zinc-type Protein Sequence Similarity - InterPro Domain: IPR002085
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR013149 Alcohol dehydrogenase, C-terminal Protein Sequence Similarity - InterPro Domain: IPR013149
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR020843 Polyketide synthase, enoylreductase domain Protein Sequence Similarity - InterPro Domain: IPR020843
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Person Approved EC number 1.-.-.- Published Annotation - Swiss-Prot Accession Number: P76113 Feb 2006
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GI:226510941 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P76113 Published Annotation - Swiss-Prot Accession Number: P76113 Jan 2005
Automated Process Approved db xref UniProtKB/Swiss-Prot:P76113 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0004834 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG13772 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved function enzyme; Not classified Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved note putative oxidoreductase Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC74531.4 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR013149
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0008270 zinc ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002085
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR002085
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002869 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002505 yncB CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002464 yncB CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0002179 curA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002658 curA CDS
Ortholog
Automated Process Uncurated Go view Brenneria salicis ATCC 15712 [T] AMK-0000824 CDS
Automated Process Uncurated Go view Brenneria sp. EniD312 AKG-0004098 CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0003635 CDS
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0002297 curA CDS
Automated Process Uncurated Go view Citrobacter freundii ATCC 8090 [T] AVI-0002961 curA CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0002841 CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC 49946 ACW-0299896 CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC BAA-2158 APN-0001352 yncB CDS
Automated Process Uncurated Go view Erwinia tasmaniensis Et1/99 [T] AFI-0002337 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0004007 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0005455 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0010036 CDS
Person Uncurated Go view Escherichia coli ATCC 11775 [T] AMC-0005373 pseudogene
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0007967 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0005310 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005112 CDS
Person Uncurated Go view Escherichia coli CFT073 (UPEC) ABR-0082018 curA pseudogene
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0001560 CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0001882 CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0005294 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0006305 CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0006070 CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0003312 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0005434 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0009799 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0007978 CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007086 CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0006895 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0006962 CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0011370 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0008035 CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0008465 CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0007054 CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0007158 CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0008814 CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0026044 yncB CDS
Automated Process Approved Go view Escherichia coli HS ADR-0006212 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0001358 yncB CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0001490 yncB CDS
Person Uncurated Go view Escherichia coli Nissle 1917 AML-0005761 pseudogene
Automated Process Approved Go view Escherichia coli SE11 AFS-0001561 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0001723 CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0132021 yncB CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0002074 CDS
Automated Process Uncurated Go view Ewingella americana ATCC 33852 [T] AMA-0000829 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0001918 yncB CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0004626 CDS
Automated Process Uncurated Go view Pantoea agglomerans IG1 APM-0001256 CDS
Automated Process Uncurated Go view Pantoea agglomerans SL1-M5 ALY-0003792 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0001234 yncB CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0002872 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0001941 yncB CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0002282 CDS
Automated Process Uncurated Go view Pantoea stewartii DC283 ACV-0290068 yncB CDS
Automated Process Uncurated Go view Pantoea vagans C9-1 ALK-0005091 yncB CDS
Person Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0060667 CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0000293 CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0002878 CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0004964 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0005746 CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0001442 CDS
Person Uncurated Go view Salmonella Choleraesuis SC-B67 ADB-0001860 yncB CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0006023 CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0004778 yncB CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0004668 yncB CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0004886 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0006131 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0005070 CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0005121 CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0004581 CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0005202 CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0006070 CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0004713 CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0001282 CDS
Person Uncurated Go view Salmonella Paratyphi A ATCC 9150 ADA-0001279 yncB CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0001709 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0006317 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0005303 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0005791 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0005129 CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0108075 CDS
Person Uncurated Go view Salmonella Typhi Ty2 ABS-0083213 CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0001926 yncB CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0095230 yncB CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0007767 CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0005770 CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0006959 CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0002788 CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0007129 CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0004108 CDS
Person Approved Go view Shigella dysenteriae 197 ADU-0001990 yncB CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0072995 yncB CDS
Person Uncurated Go view Shigella flexneri 301 ABT-0088066 yncB CDS
Automated Process Uncurated Go view Shigella flexneri 8401 BAG-0001881 yncB CDS
Person Uncurated Go view Shigella sonnei 046 ADD-0001839 yncB CDS
Automated Process Uncurated Go view Yersinia enterocolitica 8081 BAH-0007405 CDS
Automated Process Uncurated Go view Yersinia frederiksenii ATCC 33641 [T] AEI-0000394 curA CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0003277 curA CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0013377 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0003894 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 1514027 to 1525064
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0004807ydcUCDSforward15138311514772Upstream
ABE-0004809ydcVCDSforward15147621515556Upstream
ABE-0285723matS11protein_bindforward15149541514966Upstream
ABE-0004813patDCDSforward15155781517002Upstream
ABE-0285182yncLCDScomplement15170991517194Upstream
ABE-0004818ortTCDSforward15173891517562Upstream
ABE-0004821ydcYCDSforward15176481517881Upstream
ABE-0004823ydcZCDScomplement15178821518331Upstream
ABE-0004827mnaTCDScomplement15183281518846Upstream
ABE-0004834curACDSforward15190271520064Matches
ABE-0004837mcbRCDSforward15202621520927Downstream
ABE-0004839yncDCDScomplement15209631523065Downstream
ABE-0004843yncECDSforward15233071524368Downstream
ABE-0004845ansPCDScomplement15244811525980Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.