Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0005092 (sad) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0005092 showshow history
Names
sad JW5247 ECK1518 yneI b1525
Product
succinate semialdehyde dehydrogenase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome complement 1613315 1614703 1389 463
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR012303 (IPR012303 (DEPRECATED) NAD-dependent aldehyde dehydrogenase) Apr 2008
Automated Process Approved IPR015590 (IPR015590 Aldehyde dehydrogenase domain) Apr 2008
Automated Process Approved IPR016161 (IPR016161 Aldehyde/histidinol dehydrogenase) Jul 2018
Automated Process Approved PF00171 (PF00171 Aldehyde dehydrogenase family) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Uncurated GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Uncurated name sad Published Annotation - PubMed ID: 3276667
Reference: Escherichia coli K-12 		Mar 2009
Person Approved synonym yneI Published Annotation - Swiss-Prot Accession Number: P76149 Aug 2002
Person Approved synonym ECK1518 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW5247 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b1525 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Approved product succinate semialdehyde dehydrogenase Experimental - PubMed ID: 17873044
Reference: Escherichia coli BW25113 		Jan 2009
Automated Process Approved alternate product name succinate semialdehyde dehydrogenase, NAD(P)+-dependent Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Protein Family
Automated Process Approved protein family IPR012303 (DEPRECATED) NAD-dependent aldehyde dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR012303
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR016161 Aldehyde/histidinol dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR015590 Aldehyde dehydrogenase domain Protein Sequence Similarity - InterPro Domain: IPR015590
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF00171 Aldehyde dehydrogenase family Protein Sequence Similarity - PFAM Model Name: PF00171
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Automated Process Uncurated EC number 1.-.-.- Published Annotation - Database Name: EC2GO: GO:0016491
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Approved EC number 1.2.1.- Published Annotation - Swiss-Prot Accession Number: P76149 Feb 2006
Automated Process Approved EC number 1.2.1.24 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0005092 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:947440 Published Annotation - Entrez Gene Database ID: 947440
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:87081926 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P76149 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P76149 Published Annotation - Swiss-Prot Accession Number: P76149 Jan 2005
Automated Process Approved db xref EcoGene:EG13817 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function degrades succinate semialdehyde to prevent toxic accumulation Published Annotation - PubMed ID: 17873044
Reference: Escherichia coli BW25113 		Jan 2009
Automated Process Approved note putative aldehyde dehydrogenase Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC74598.2 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 9.97
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR015590, IPR016161
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0003882 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002654 sad CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002693 sad CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0004284 sad CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0000152 sad CDS
Ortholog
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0002082 yneI CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0001889 CDS
Automated Process Uncurated Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0002232 sad CDS
Automated Process Uncurated Go view Citrobacter freundii ATCC 8090 [T] AVI-0002875 sad CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0002713 CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC 49946 ACW-0307243 EAM_P111 CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC BAA-2158 APN-0000040 aldD CDS
Automated Process Uncurated Go view Erwinia tasmaniensis Et1/99 [T] AFI-0000817 aldD CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0003956 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0005555 CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0001521 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0010124 CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0001483 yneI CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0002833 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0007874 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0005390 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005024 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0078063 sad CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0001697 yneI CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0001961 yneI CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0005193 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0008023 CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0001760 yneI CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0006164 CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0003400 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0005517 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0009881 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0008062 CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0007003 CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0006978 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0006879 CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0011455 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0008121 CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0008382 CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0006971 CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0007074 CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0008731 CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0025951 yneI CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0009415 sad CDS
Automated Process Approved Go view Escherichia coli HS ADR-0006283 CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0001955 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0001430 yneI CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0001565 yneI CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0001824 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0001863 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0001780 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0001752 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0175898 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0001644 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0001646 CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0132102 yneI CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0000686 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0001751 yneI CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0001639 yneI CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0004547 CDS
Automated Process Uncurated Go view Musicola paradisiaca Ech703 AGA-0005804 CDS
Automated Process Uncurated Go view Pantoea agglomerans IG1 APM-0004236 CDS
Automated Process Uncurated Go view Pantoea agglomerans SL1-M5 ALY-0000774 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0003989 yneI CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0004655 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0004302 yneI CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0004544 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0007041 CDS
Automated Process Uncurated Go view Pantoea sp. aB AJV-0002083 CDS
Automated Process Uncurated Go view Pantoea stewartii DC283 ACV-0286619 CDS
Automated Process Uncurated Go view Pantoea vagans C9-1 ALK-0007925 yneI CDS
Person Uncurated Go view Pseudomonas syringae pv. tomato DC3000 ADG-0002705 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0005820 CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0001518 CDS
Person Uncurated Go view Salmonella Choleraesuis SC-B67 ADB-0001792 yneI CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0006081 CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0004962 yneI CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0004823 yneI CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0004952 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0006059 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0004996 CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0005045 CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0004506 CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0005127 CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0006004 CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0004782 CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0001340 CDS
Person Uncurated Go view Salmonella Paratyphi A ATCC 9150 ADA-0001331 yneI CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0001791 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0006247 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0005377 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0005716 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0005047 CDS
Person Uncurated Go view Salmonella Typhi CT18 ABX-0108177 CDS
Person Uncurated Go view Salmonella Typhi Ty2 ABS-0083159 CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0001844 yneI CDS
Person Uncurated Go view Salmonella Typhimurium LT2 [T] ABU-0095053 yneI CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0007838 CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0005703 CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0007056 CDS
Person Approved Go view Shigella boydii 227 ADV-0001819 CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0007091 CDS
Person Approved Go view Shigella dysenteriae 197 ADU-0001879 CDS
Person Uncurated Go view Shigella flexneri 2457T ABQ-0072783 sad pseudogene
Person Approved Go view Shigella sonnei 046 ADD-0001738 yneI CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0013717 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0003799 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB22195mutantTn5 InsertionRequest the StrainABE-0005092sadb1525::Tn5KAN-I-SceI at position 1083 in Minus orientation ,+ pKD460Blattner Laboratory
FB23125mutantTn5 InsertionRequest the StrainABE-0005092sadb1525::Tn5KAN-I-SceI at position 1083 in Minus orientation ,- pKD465Tim Durfee (durf@genome.wisc.edu)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 1608315 to 1619703
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0005072yneECDScomplement16081081609022Downstream
ABE-0005076uxaBCDScomplement16092291610680Downstream
ABE-0005081dgcFpseudogenecomplement16109071611892Downstream
ABE-0005084yneGCDScomplement16119661612325Downstream
ABE-0005086glsBCDScomplement16123251613251Downstream
ABE-0005092sadCDScomplement16133151614703Matches
ABE-0005096yneJCDSforward16148041615685Upstream
ABE-0005100yneKCDSforward16157631616878Upstream
ABE-0005103ydeACDSforward16170281618218Upstream
ABE-0005106marCCDScomplement16182431618908Upstream
ABE-0005110marRCDSforward16191201619554Upstream
ABE-0005112marACDSforward16195741619957Upstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.