ABE-0006753 (wbbH) - Escherichia coli K-12 MG1655 - Feature Annotation

wbbH JW2020 rfc ECK2029 yefF wzy b2035

CDS

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		Type	Annotation	Evidence	Annotated
Nomenclature
		name	wbbH	Published Annotation - PubMed ID: 9004408 Reference: Escherichia coli K-12	Apr 2020
		synonym	yefF	Published Annotation in EcoGene - EG Number: EG11982	Mar 2005
		synonym	JW2020	Published Annotation - PubMed ID: 16397293	Jan 2006
		synonym	rfc	Experimental - PubMed ID: 7517391 Reference: Escherichia coli	Jan 2006
		synonym	wzy	Published Sequence Analysis - PubMed ID: 9004408	Feb 2005
		synonym	ECK2029	Published Annotation - PubMed ID: 16397293	Jan 2006
		locus tag	b2035	Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu	May 2004
Product
		product	O-antigen polymerase	Experimental - PubMed ID: 7517390 Reference: Escherichia coli	Mar 2005
		alternate product name	repeat unit polymerase	Published Sequence Analysis - PubMed ID: 9004408	Mar 2005
Other
		MultiFun	6.3 (cell structure; surface antigens (ECA, O antigen of LPS))	Published Annotation - MultiFun Database Name: MultiFun	Feb 2002
		MultiFun	1.6.3.1 (metabolism; macromolecules (cellular constituent) biosynthesis; lipopolysaccharide; O antigen)	Published Annotation - MultiFun Database Name: MultiFun	Feb 2002
		codon start	1	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
		db xref	UniProtKB/Swiss-Prot:P37748	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
		db xref	ASAP:ABE-0006753	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
		db xref	EcoGene:EG11982	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
		db xref	GI:1788347	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
		db xref	NCBI_gi:510254	Published Annotation - GenPept Accession Number: AAC31633	Mar 2005
		db xref	NCBI_gi:508243	Published Annotation - GenPept Accession Number: AAB88404	Mar 2005
		db xref	GeneID:945179	Published Annotation - Entrez Gene Database ID: 945179 Reference: Escherichia coli K-12 MG1655	Jun 2009
		db xref	UniProtKB:P37748	Published Annotation - Swiss-Prot Accession Number: P37748	Jan 2005
		function	enzyme; Macromolecule metabolism: Lipopolysaccharide	Published Annotation - GenBank Accession Number: U00096 Reference: Escherichia coli MG1655	Oct 1998
		note	GO_function: GO:0042280 - cell surface antigen activity, host-interacting; GO_function: GO:0008755 - O antigen polymerase activity; GO_process: GO:0009243 - O antigen biosynthetic process; GO_process: GO:0009103 - lipopolysaccharide biosynthetic process	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
		protein id	AAC75096.1	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
		subcellular localization	Cytoplasmic Membrane	Predicted by PSORTb - PSORTb Final_Score: 10.00 Reference: Escherichia coli K-12 MG1655	Feb 2008
		subsystem	component of in silico model iAF1260	Experimental - PubMed ID: 17593909 Reference: Escherichia coli K-12 MG1655	Jan 2009
		transl table	11	Published Annotation - GenBank Accession Number: U00096.3 Reference: Escherichia coli K-12 MG1655	Oct 2013
Gene Ontology
		GO biological process	GO:0009103 lipopolysaccharide biosynthetic process	Experimental - PubMed ID: 7517390 Reference: Escherichia coli	Mar 2005
		GO biological process	GO:0009243 O antigen biosynthetic process	Experimental - PubMed ID: 7517390 Reference: Escherichia coli	Mar 2005
		GO cellular component	GO:0005886 plasma membrane	GO Inferred from Electronic Annotation - PubMed ID: 15501914 Reference: Escherichia coli K-12 MG1655	Feb 2008
		GO molecular function	GO:0008755 O antigen polymerase activity	Experimental - PubMed ID: 7517390 Reference: Escherichia coli	Mar 2005

Select	SetName	SetDetails	Notes
	stringent response	transcriptional profile of the stringent response	None
	Recombinant heat-shock data	expression data for recombinant strain under heat shock	These data are from the Harcum laboratory. (Jeremy Glasner)
	Suppressor tRNA expression	experiment comparing transcript levels in cells with and without suppressor tRNA expression	These data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
	Recombinant E. coli expression	experiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG	These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
	Aerobic shift	Aerobic shift	These data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
	Calibrator	Calibrated microarray experiments (50 hybridizations)	This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
	AffyData1	Affymetrix Experiments (data from 41 chip hybridizations)	This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 2101060 to 2112226

FeatureID	Name	Feature Type	Strand	Left End	Right End	Relationship
ABE-0000001		source	forward	1	4641652	Contains
ABE-0006737	gnd	CDS	complement	2099862	2101268	Downstream
ABE-0285061	wbbL_2	CDSp	complement	2101396	2101677	Downstream
ABE-0285104	wbbL	pseudogene	complement	2101396	2101744	(Interval #2) Downstream
ABE-0006740		is_element	forward	2101749	2102943	Downstream
ABE-0285482		mobile_element	complement	2101749	2102943	Downstream
ABE-0006742	insH7	CDS	complement	2101895	2102875	Downstream
ABE-0006744	wbbL_1	CDSp	complement	2102916	2103389	Downstream
ABE-0285104	wbbL	pseudogene	complement	2102944	2103389	(Interval #1) Downstream
ABE-0006747	wbbK	CDS	complement	2103391	2104509	Downstream
ABE-0006749	wbbJ	CDS	complement	2104494	2105084	Downstream
ABE-0006751	wbbI	CDS	complement	2105065	2106057	Downstream
ABE-0006753	wbbH	CDS	complement	2106060	2107226	Matches
ABE-0006755	glf	CDS	complement	2107226	2108329	Overlaps Upstream
ABE-0006757	rfbX	CDS	complement	2108337	2109584	Upstream
ABE-0006759	rfbC	CDS	complement	2109581	2110138	Upstream
ABE-0006762	rfbA	CDS	complement	2110138	2111019	Upstream
ABE-0006764	rfbD	CDS	complement	2111077	2111976	Upstream
ABE-0006766	rfbB	CDS	complement	2111976	2113061	Upstream

All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.