Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0007927 (xapA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0007927 showshow history
Names
xapA JW2398 ECK2401 pndA b2407
Product
purine nucleoside phosphorylase II
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome complement 2524045 2524878 834 278
Sequence

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View sequence with flanking regions: bases upstream and bases downstream

Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR010943 (IPR010943 Xanthosine phosphorylase) Apr 2008
Automated Process Approved IPR001369 (IPR001369 (DEPRECATED) PNP/MTAP phosphorylase) Apr 2008
Automated Process Approved IPR011268 (IPR011268 Purine nucleoside phosphorylase) Apr 2008
Automated Process Approved IPR000845 (IPR000845 Nucleoside phosphorylase domain) Jul 2018
Automated Process Approved IPR035994 (IPR035994 Nucleoside phosphorylase superfamily) Jul 2018
Automated Process Approved PF01048 (PF01048 Phosphorylase superfamily) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0015949 nucleobase-containing small molecule interconversion Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0009116 nucleoside metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000845, IPR035994
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0055086 nucleobase-containing small molecule metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010943
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO biological process GO:0006139 nucleobase-containing compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011268
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010943
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000845, IPR035994
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0016763 pentosyltransferase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001369
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0004731 purine-nucleoside phosphorylase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011268
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name xapA Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym JW2398 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ECK2401 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym pndA Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved locus tag b2407 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Approved product purine nucleoside phosphorylase II Published Annotation - PubMed ID: 16397293 Jan 2006
Person Uncurated alternate product name xanthosine phosphorylase (purine nucleoside phosphorylase) Published Annotation - Database Name: GenProtEC Jan 2006
Person Approved alternate product name xanthosine phosphorylase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Automated Process Approved alternate product name purine nucleoside phosphorylase II Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Protein Family
Automated Process Approved protein family IPR035994 Nucleoside phosphorylase superfamily Protein Sequence Similarity - InterPro Domain: IPR035994
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR000845 Nucleoside phosphorylase domain Protein Sequence Similarity - InterPro Domain: IPR000845
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR011268 Purine nucleoside phosphorylase Protein Sequence Similarity - InterPro Domain: IPR011268
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR001369 (DEPRECATED) PNP/MTAP phosphorylase Protein Sequence Similarity - InterPro Domain: IPR001369
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF01048 Phosphorylase superfamily Protein Sequence Similarity - PFAM Model Name: PF01048
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR010943 Xanthosine phosphorylase Protein Sequence Similarity - InterPro Domain: IPR010943
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Person Approved EC number 2.4.2.- Published Annotation - Swiss-Prot Accession Number: P45563 Feb 2006
Person Uncurated MultiFun 1.7.33 (metabolism; central intermediary metabolism; nucleotide and nucleoside conversions) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG20250 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:946878 Published Annotation - Entrez Gene Database ID: 946878
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:1788746 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P45563 Published Annotation - Swiss-Prot Accession Number: P45563 Jan 2005
Automated Process Approved db xref UniProtKB/Swiss-Prot:P45563 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0007927 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Central intermediary metabolism: Nucleotide interconversions Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note xanthosine phosphorylase; GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC75460.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Unknown Predicted by PSORTb - PSORTb Final_Score: 2.00
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0015949 nucleobase-containing small molecule interconversion Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0055086 nucleobase-containing small molecule metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010943
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0009116 nucleoside metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000845, IPR035994
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO biological process GO:0006139 nucleobase-containing compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011268
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010943
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0016763 pentosyltransferase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001369
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000845, IPR035994
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0004731 purine-nucleoside phosphorylase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011268
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0004612 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0003452 xapA CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0003453 xapA CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0003609 xapA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0003775 xapA CDS
Ortholog
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0001412 xapA CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0002812 xapA CDS
Automated Process Uncurated Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0003254 xapA CDS
Automated Process Uncurated Go view Citrobacter freundii ATCC 8090 [T] AVI-0003937 xapA CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0003124 xapA CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0002450 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0008820 xapA CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0002373 xapA CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0001890 xapA CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0010400 xapA CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0079084 xapA CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0003227 xapA CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0002749 xapA CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0009954 xapA CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0002956 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0002263 xapA CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0002484 xapA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0002970 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0002772 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0176931 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0002745 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0002560 xapA CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0002747 xapA CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0001989 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0006734 xapA CDS
Person Uncurated Go view Salmonella Choleraesuis SC-B67 ADB-0002832 xapA CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0007048 xapA CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0007785 xapA CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0007391 xapA CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0006098 xapA CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0007043 xapA CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0006925 xapA CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0007138 xapA CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0006392 xapA CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0006167 xapA CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0006977 xapA CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0008160 xapA CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0000540 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0007223 xapA CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0004959 xapA CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0006733 xapA CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0008092 xapA CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0110563 xapA CDS
Person Uncurated Go view Salmonella Typhi Ty2 ABS-0082147 xapA CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0002982 CDS
Person Uncurated Go view Salmonella Typhimurium LT2 [T] ABU-0097714 xapA CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0006852 xapA CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0004354 xapA CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0006022 xapA CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0001632 xapA CDS
Automated Process Uncurated Go view Yersinia frederiksenii ATCC 33641 [T] AEI-0000442 xapA CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0002672 xapA CDS
Automated Process Uncurated Go view Yersinia mollaretii ATCC 43969 [T] AEJ-0001256 CDS
Person Uncurated Go view Yersinia pestis 91001 (biovar Microtus) ACQ-0236545 xapA CDS
Automated Process Uncurated Go view Yersinia pestis Antiqua (biovar Antiqua) BAE-0001310 xapA CDS
Automated Process Uncurated Go view Yersinia pestis B42003004 (biovar Antiqua) BAL-0005237 xapA CDS
Automated Process Uncurated Go view Yersinia pestis CA88-4125 (biovar Orientalis) BAF-0002197 xapA CDS
Person Uncurated Go view Yersinia pestis CO92 (biovar Orientalis) ABY-0119115 xapA CDS
Automated Process Uncurated Go view Yersinia pestis E1979001 (biovar Antiqua) BAM-0008077 xapA CDS
Automated Process Uncurated Go view Yersinia pestis F1991016 (biovar Orientalis) BAQ-0004770 xapA CDS
Automated Process Uncurated Go view Yersinia pestis FV-1 (biovar Orientalis) BAK-0001937 CDS
Automated Process Uncurated Go view Yersinia pestis K1973002 (biovar Mediaevalis) BAO-0005348 xapA CDS
Automated Process Uncurated Go view Yersinia pestis Nepal516 (biovar Antiqua) BAD-0003404 xapA CDS
Automated Process Uncurated Go view Yersinia pestis Pestoides F (biovar Pestoides) BAI-0003037 CDS
Automated Process Uncurated Go view Yersinia pestis UG05-0454 (biovar Antiqua) BAN-0006312 xapA CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis IP31758 ADS-0006814 xapA CDS
Person Uncurated Go view Yersinia pseudotuberculosis IP32953 ACZ-0001269 xapA CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis PB1/+ AFV-0001512 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis YPIII AFW-0003460 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0007202 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0002581 xapA CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB20785mutantTn5 InsertionRequest the StrainABE-0007927xapAxapA::Tn5KAN-2 at position 192 in Minus orientation ,+ pKD460Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 2519045 to 2529878
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0007909yfeDCDSforward25188132519205Downstream
ABE-0007911gltXCDScomplement25192572520672Downstream
ABE-0007914valUtRNAforward25209312521006Downstream
ABE-0007916valXtRNAforward25210512521126Downstream
ABE-0007918valYtRNAforward25211732521248Downstream
ABE-0007920lysVtRNAforward25212532521328Downstream
ABE-0285515repeat_regionforward25215382521566Downstream
ABE-0007922xapRCDScomplement25215932522477Downstream
ABE-0007925xapBCDScomplement25227292523985Downstream
ABE-0007927xapACDScomplement25240452524878Matches
ABE-0007930yfeNCDSforward25251272525891Upstream
ABE-0007932yfeRCDScomplement25259302526856Upstream
ABE-0007936yfeHCDSforward25269462527944Upstream
ABE-0285067ypeBCDScomplement25279412528159Upstream
ABE-0007938ligACDScomplement25281612530176Upstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.