Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0008115 (talA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0008115 showshow history
Names
talA JW2448 ECK2459 b2464
Product
transaldolase A
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 2578666 2579616 951 317
Sequence

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View sequence with flanking regions: bases upstream and bases downstream

Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR013785 (IPR013785 Aldolase-type TIM barrel) Apr 2008
Automated Process Approved IPR001585 (IPR001585 Transaldolase/Fructose-6-phosphate aldolase) Apr 2008
Automated Process Approved IPR004730 (IPR004730 Transaldolase type 1) Apr 2008
Automated Process Approved PF00923 (PF00923 Transaldolase/Fructose-6-phosphate aldolase) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0009052 pentose-phosphate shunt, non-oxidative branch Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0005975 carbohydrate metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001585
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0006098 pentose-phosphate shunt GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004730
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013785
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004730
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0004801 transaldolase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004730
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013785
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name talA Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym ECK2459 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW2448 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b2464 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Approved product transaldolase A Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved alternate product name transaldolase A Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Protein Family
Automated Process Approved protein family IPR013785 Aldolase-type TIM barrel Protein Sequence Similarity - InterPro Domain: IPR013785
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF00923 Transaldolase/Fructose-6-phosphate aldolase Protein Sequence Similarity - PFAM Model Name: PF00923
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR004730 Transaldolase type 1 Protein Sequence Similarity - InterPro Domain: IPR004730
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR001585 Transaldolase/Fructose-6-phosphate aldolase Protein Sequence Similarity - InterPro Domain: IPR001585
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Person Approved EC number 2.2.1.2 Published Annotation - Swiss-Prot Accession Number: P0A867 Feb 2006
Person Uncurated MultiFun 1.7.3 (metabolism; central intermediary metabolism; pentose phosphate shunt, non-oxidative branch) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0008115 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P0A867 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG11797 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:947006 Published Annotation - Entrez Gene Database ID: 947006
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Person Approved db xref UniProtKB:P0A867 Published Annotation - Swiss-Prot Accession Number: P0A867 Jan 2006
Automated Process Approved db xref GI:1788807 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Central intermediary metabolism: Non-oxidative branch, pentose pathway Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note GO_process: GO:0009052 - pentose-phosphate shunt, non-oxidative branch Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC75517.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Uncurated regulation regulated by nutritional source; expression of talA is down-regulated in complex medium compared to glucose minimal medium, as determined by RT-PCR Experimental - PubMed ID: 11350954
Reference: Escherichia coli K-12 		Sep 2007
Person Uncurated regulation regulated by creC (ASAP:ABE-0014430); activation of talA expression under nutrient limiting conditions was not observed in a creC null mutant, as determined by RT-PCR Experimental - PubMed ID: 11350954
Reference: Escherichia coli K-12 		Sep 2007
Person Uncurated regulation expression regulated by acetate; expression is induced by acetate Experimental - PubMed ID: 11244055
Reference: Escherichia coli ATCC43888 (EHEC) 		Nov 2005
Automated Process Uncurated subcellular localization Unknown Predicted by PSORTb - PSORTb Final_Score: 2.00
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0009052 pentose-phosphate shunt, non-oxidative branch Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0005975 carbohydrate metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001585
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013785
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0006098 pentose-phosphate shunt GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004730
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004730
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0004801 transaldolase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004730
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013785
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002910 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002283 talA CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002376 talA CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0002458 talA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002392 talA CDS
Ortholog
Person Approved Go view Buchnera aphidicola APS ABZ-0129363 talA CDS
Person Approved Go view Buchnera aphidicola Bp ABW-0104813 talA CDS
Person Approved Go view Buchnera aphidicola Sg [T] ABV-0104199 talA CDS
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0003196 talA CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0000887 talA CDS
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0003301 talA CDS
Person Approved Go view Dickeya dadantii 3937 ABF-0016744 talA CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0000816 CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0003896 talA CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC 49946 ACW-0303653 talA CDS
Automated Process Uncurated Go view Erwinia amylovora ATCC BAA-2158 APN-0002698 talA CDS
Automated Process Uncurated Go view Erwinia tasmaniensis Et1/99 [T] AFI-0001129 talA CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0003083 tal1 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0006801 tal1 CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0002496 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0008768 tal CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0002418 talA CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0001843 talA CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0006765 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0006765 tal1 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0007934 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0079133 talA CDS
Person Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0002803 talA pseudogene
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0003296 CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0006776 tal1 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0008518 tal1 CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0002858 talA CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0007176 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0000800 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0007028 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0005549 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0005023 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0006643 tal1 CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0008525 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0006292 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0006317 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0008176 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0007974 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0006656 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0006573 tal1 CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0008101 tal1 CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0027428 talA CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0008053 tal CDS
Automated Process Approved Go view Escherichia coli HS ADR-0007266 tal1 CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0003122 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0002320 talA CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0002533 talA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0003130 tal CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0002901 tal CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0002920 tal CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0002819 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0176988 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0002793 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0002609 tal1 CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0133345 talA CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0003646 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0002796 talA CDS
Automated Process Uncurated Go view Ewingella americana ATCC 33852 [T] AMA-0002558 talA CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0002807 talA CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0001130 talA CDS
Automated Process Uncurated Go view Pantoea agglomerans IG1 APM-0002144 CDS
Automated Process Uncurated Go view Pantoea agglomerans SL1-M5 ALY-0003508 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0002106 talA CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0001907 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0002859 talA CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0001283 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0010595 CDS
Automated Process Uncurated Go view Pantoea sp. aB AJV-0001079 CDS
Automated Process Uncurated Go view Pantoea stewartii DC283 ACV-0290914 talA CDS
Automated Process Uncurated Go view Pantoea vagans C9-1 ALK-0005977 talA CDS
Person Uncurated Go view Pectobacterium atrosepticum SCRI1043 ABL-0061097 talA CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0000470 talA CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0001315 talA CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0005339 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0006785 tal1 CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0000424 CDS
Person Approved Go view Salmonella Choleraesuis SC-B67 ADB-0002889 talA CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0007100 tal1 CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0007941 talA CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0007540 talA CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0006048 tal1 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0007094 tal1 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0006977 tal1 CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0007089 tal CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0006443 tal1 CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0006218 tal1 CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0007028 tal1 CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0008108 tal CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0000397 CDS
Person Approved Go view Salmonella Paratyphi A ATCC 9150 ADA-0000396 talA CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0000485 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0007274 tal1 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0004908 tal1 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0006782 tal CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0007442 tal CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0110696 talA CDS
Person Approved Go view Salmonella Typhi Ty2 ABS-0082098 talA CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0003038 talA CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0097867 talA CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0006801 tal1 CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0004303 tal1 CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0006075 tal1 CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0002212 tal CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0008239 tal1 CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0073806 talA CDS
Person Approved Go view Shigella flexneri 301 ABT-0088764 talA CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0002683 talA CDS
Person Approved Go view Shigella sonnei 046 ADD-0002780 talA CDS
Person Uncurated Go view Wigglesworthia morsitans AEQ-0000112 talA CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB22424mutantTn5 InsertionRequest the StrainABE-0008115talAtalA::Tn5KAN-I-SceI at position 691 in Plus orientation ,+ pKD460Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 2573666 to 2584616
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0008100eutTCDScomplement25735022574305Upstream
ABE-0008102eutQCDScomplement25743022575003Upstream
ABE-0008105eutPCDScomplement25749782575457Upstream
ABE-0008108eutSCDScomplement25754702575805Upstream
ABE-0008111maeBCDScomplement25760982578377Upstream
ABE-0008115talACDSforward25786662579616Matches
ABE-0008117tktBCDSforward25796362581639Downstream
ABE-0285522repeat_regionforward25816482581716Downstream
ABE-0008120ypfGCDScomplement25817342582777Downstream
ABE-0008123nudKCDScomplement25829032583478Downstream
ABE-0008127aegACDScomplement25835462585525Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.