Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0008756 (lhgD) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0008756 showshow history
Names
lhgD lhgO JW2635 ECK2654 ygaF b2660
Product
L-2-hydroxyglutarate dehydrogenase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 2789982 2791250 1269 423
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR015657 (IPR015657 Aminobutyraldehyde dehydrogenase) Apr 2008
Automated Process Approved IPR006076 (IPR006076 FAD dependent oxidoreductase) Apr 2008
Automated Process Approved IPR036188 (IPR036188 FAD/NAD(P)-binding domain superfamily) Jul 2018
Automated Process Approved PF01266 (PF01266 FAD dependent oxidoreductase) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Approved GO biological process GO:0006118 (OBSOLETE) electron transport GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006076
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR006076
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006076
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name lhgD Experimental - PubMed ID: 30498244
Reference: Escherichia coli K-12 BW25113 		Apr 2020
Person Approved synonym ECK2654 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW2635 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ygaF Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Uncurated synonym lhgO Published Annotation - PubMed ID: 18390652
Reference: Escherichia coli K-12 MG1655 		Apr 2009
Person Approved locus tag b2660 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Approved product L-2-hydroxyglutarate dehydrogenase Experimental - PubMed ID: 30498244
Reference: Escherichia coli K-12 BW25113 		Apr 2020
Person Uncurated alternate product name L-2-hydroxyglutarate oxidase Experimental - PubMed ID: 18390652
Reference: Escherichia coli K-12 MG1655 		Feb 2021
Protein Family
Automated Process Approved protein family IPR015657 Aminobutyraldehyde dehydrogenase Protein Sequence Similarity - InterPro Domain: IPR015657
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR036188 FAD/NAD(P)-binding domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036188
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR006076 FAD dependent oxidoreductase Protein Sequence Similarity - InterPro Domain: IPR006076
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF01266 FAD dependent oxidoreductase Protein Sequence Similarity - PFAM Model Name: PF01266
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Person Uncurated EC number 1.1.99.2 Experimental - PubMed ID: 30498244
Reference: Escherichia coli K-12 BW25113 		Feb 2021
Person Uncurated EC number 1.4.3.3 Protein Sequence Similarity - InterPro Domain: IPR006076
Reference: Escherichia coli K-12 MG1655 		Dec 2008
Automated Process Uncurated EC number 1.-.-.- Published Annotation - Database Name: EC2GO: GO:0016491
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P37339 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P37339 Published Annotation - Swiss-Prot Accession Number: P37339 Jan 2005
Automated Process Approved db xref GeneID:948069 Published Annotation - Entrez Gene Database ID: 948069
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:87082148 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0008756 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG12387 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC75707.2 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Unknown Predicted by PSORTb - PSORTb Final_Score: 2.00
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR006076
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO biological process GO:0006118 (OBSOLETE) electron transport GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006076
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006076
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0006821 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002995 lhgO CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0003269 lhgO CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0004604 lhgO CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002960 lhgD CDS
Ortholog
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0003479 lhgO CDS
Automated Process Uncurated Go view Citrobacter freundii ATCC 8090 [T] AVI-0004206 lhgO CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0002887 CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0002647 CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0002657 ygaF CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0001638 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0006566 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007355 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0007305 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0079357 lhgD CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0003040 lhgO CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0003508 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0009927 CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0003101 ihgO CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0007377 CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0001224 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0007241 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0005761 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0005237 CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0008999 CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0008738 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007459 CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0006531 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007355 CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0008173 CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0008034 CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0008257 CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0009828 CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0027632 ygaF CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0006298 lhgO CDS
Automated Process Approved Go view Escherichia coli HS ADR-0007469 CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0001424 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0002499 ygaF CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0002728 ygaF CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0003230 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0003142 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0003074 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0002965 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0177214 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0002965 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0002778 CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0133550 ygaF CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0000808 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0003024 ygaF CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0004318 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0000258 ygaF CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0002923 CDS
Person Uncurated Go view Pseudomonas syringae pv. tomato DC3000 ADG-0005743 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0007070 CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0000187 CDS
Person Uncurated Go view Salmonella Choleraesuis SC-B67 ADB-0003189 ygaF CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0007349 CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0008608 ygaF CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0006619 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0007330 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0008176 CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0006807 CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0008035 CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0006453 CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0007346 CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0005712 CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0002675 CDS
Person Uncurated Go view Salmonella Paratyphi A ATCC 9150 ADA-0002646 ygaF CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0003481 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0007509 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0007845 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0007007 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0007896 CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0111237 ygaF CDS
Person Uncurated Go view Salmonella Typhi Ty2 ABS-0084402 ygaF CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0003371 ygaF CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0098749 ygaF CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0006515 CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0009035 CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0006714 CDS
Person Approved Go view Shigella boydii 227 ADV-0003141 ygaF CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0008634 CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0074032 ygaF CDS
Person Approved Go view Shigella flexneri 301 ABT-0088938 ygaF CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0003034 ygaF CDS
Person Approved Go view Shigella sonnei 046 ADD-0003072 ygaF CDS
Person Uncurated Go view Vibrio cholerae N16961 ADH-0003036 VCA0147 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0009621 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0001678 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 2784982 to 2796250
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0285127ypjCpseudogenecomplement27836382785011Upstream
ABE-0008727ypjC_1CDSpcomplement27845292785011Upstream
ABE-0008733ileYtRNAcomplement27857622785837Upstream
ABE-0008739ygaQ_1CDSpforward27863972786729Upstream
ABE-0285128ygaQpseudogeneforward27863972788649Upstream
ABE-0174112ygaQ_2CDSpforward27867482787434Upstream
ABE-0008747ygaQ_3CDSpforward27876422788238Upstream
ABE-0008751ygaQ_4CDSpforward27883772788649Upstream
ABE-0008754glaHCDSforward27889852789962Upstream
ABE-0008756lhgDCDSforward27899822791250Matches
ABE-0008758gabDCDSforward27912732792721Downstream
ABE-0008760gabTCDSforward27927352794015Downstream
ABE-0285535repeat_regionforward27940282794163Downstream
ABE-0008763gabPCDSforward27942532795653Downstream
ABE-0008765glaRCDSforward27956742796336Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.