Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0008760 (gabT) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0008760 showshow history
Names
gabT JW2637 ECK2656 b2662
Product
4-aminobutyrate aminotransferase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 2792735 2794015 1281 427
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR005814 (IPR005814 Aminotransferase class-III) Apr 2008
Automated Process Approved IPR004632 (IPR004632 4-aminobutyrate aminotransferase, bacterial) Apr 2008
Automated Process Approved IPR015424 (IPR015424 Pyridoxal phosphate-dependent transferase) Apr 2008
Automated Process Approved IPR015421 (IPR015421 Pyridoxal phosphate-dependent transferase, major domain) Apr 2008
Automated Process Approved PF00202 (PF00202 Aminotransferase class-III) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Approved GO biological process GO:0009448 gamma-aminobutyric acid metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004632
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0009447 putrescine catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009450 gamma-aminobutyric acid catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003867 4-aminobutyrate transaminase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004632
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0030170 pyridoxal phosphate binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR005814
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008483 transaminase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR005814
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name gabT Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym ECK2656 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW2637 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b2662 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product 4-aminobutyrate aminotransferase Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 		Oct 2021
Person Approved alternate product name 4-aminobutyrate aminotransferase activity Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name 4-aminobutyrate aminotransferase, PLP-dependent Published Annotation - Database Name: GenProtEC Jan 2006
Protein Family
Automated Process Approved protein family PF00202 Aminotransferase class-III Protein Sequence Similarity - PFAM Model Name: PF00202
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR015421 Pyridoxal phosphate-dependent transferase, major domain Protein Sequence Similarity - InterPro Domain: IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR015424 Pyridoxal phosphate-dependent transferase Protein Sequence Similarity - InterPro Domain: IPR015424
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR005814 Aminotransferase class-III Protein Sequence Similarity - InterPro Domain: IPR005814
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR004632 4-aminobutyrate aminotransferase, bacterial Protein Sequence Similarity - InterPro Domain: IPR004632
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Automated Process Uncurated EC number 2.6.1.- Published Annotation - Database Name: EC2GO: GO:0008483
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Approved EC number 2.6.1.22 Published Annotation - Swiss-Prot Accession Number: P22256 Feb 2006
Person Approved EC number 2.6.1.19 Published Annotation - Swiss-Prot Accession Number: P22256 Feb 2006
Person Uncurated MultiFun 1.7.32 (metabolism; central intermediary metabolism; putrescine catabolism) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.7.31 (metabolism; central intermediary metabolism; aminobutyrate catabolism) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P22256 Published Annotation - Swiss-Prot Accession Number: P22256 Jan 2005
Automated Process Approved db xref GI:1789016 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:948067 Published Annotation - Entrez Gene Database ID: 948067
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref UniProtKB/Swiss-Prot:P22256 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG10361 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0008760 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Central intermediary metabolism: Pool, multipurpose conversions Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note 4-aminobutyrate aminotransferase activity; GO_process: GO:0009450 - gamma-aminobutyric acid catabolic process; GO_process: GO:0009447 - putrescine catabolic process Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC75709.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0009447 putrescine catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009450 gamma-aminobutyric acid catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0009448 gamma-aminobutyric acid metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004632
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003867 4-aminobutyrate transaminase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004632
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0030170 pyridoxal phosphate binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR005814
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008483 transaminase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR005814
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0000130 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0000064 puuE CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0000086 puuE CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002994 gabT CDS
Ortholog
Automated Process Uncurated Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0003481 gabT CDS
Automated Process Uncurated Go view Citrobacter freundii ATCC 8090 [T] AVI-0004208 gabT CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0002885 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0008770 gabT2 CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0002649 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0008507 gabT CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0002659 gabT CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0001636 gabT CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0006564 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007357 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0007307 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0079360 gabT CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0003042 CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0003511 gabT CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0009707 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0009925 gabT2 CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0003103 gabT CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0007379 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0001226 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0007243 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0005763 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0005239 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0009001 gabT2 CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0008740 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007457 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0006533 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007357 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0008175 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0008036 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0008259 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0009830 gabT2 CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0027634 gabT CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0006300 gabT CDS
Automated Process Approved Go view Escherichia coli HS ADR-0007471 gabT2 CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0001422 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0002500 gabT CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0002730 gabT CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0003232 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0003144 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0003076 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0002967 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0002967 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0002780 gabT2 CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0133552 gabT CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0000810 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0003026 gabT CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0004316 gabT CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0000256 gabT CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0002921 gabT CDS
Person Uncurated Go view Pseudomonas syringae pv. tomato DC3000 ADG-0000303 gabT-2 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0007072 gabT CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0000185 CDS
Person Uncurated Go view Salmonella Choleraesuis SC-B67 ADB-0003191 gabT CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0008614 gabT CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0008170 gabT CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0006617 gabT CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0007332 gabT CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0008178 gabT CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0006805 gabT CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0008037 gabT CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0006455 gabT CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0007348 gabT CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0005710 gabT CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0002677 CDS
Person Uncurated Go view Salmonella Paratyphi A ATCC 9150 ADA-0002648 gabT CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0003483 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0007511 gabT CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0007843 gabT CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0007009 gabT CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0007898 gabT CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0111243 gabT CDS
Person Uncurated Go view Salmonella Typhi Ty2 ABS-0084404 gabT CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0003373 gabT CDS
Person Uncurated Go view Salmonella Typhimurium LT2 [T] ABU-0098755 gabT CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0006513 gabT CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0009033 gabT CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0006716 gabT CDS
Person Uncurated Go view Shewanella oneidensis MR-1 ACY-0264841 gabT CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0005603 gabT2 CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0074034 gabT pseudogene
Person Uncurated Go view Shigella flexneri 301 ABT-0256083 gabT CDS
Automated Process Uncurated Go view Shigella flexneri 8401 BAG-0003032 gabT CDS
Person Approved Go view Shigella sonnei 046 ADD-0003074 gabT CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB20873mutantTn5 InsertionRequest the StrainABE-0008760gabTgabT::Tn5KAN-I-SceI at position 538 in Minus orientation ,+ pKD460Blattner Laboratory
FB20874mutantTn5 InsertionRequest the StrainABE-0008760gabTgabT::Tn5KAN-I-SceI at position 538 in Minus orientation ,- pKD465Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 2787735 to 2799015
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0285128ygaQpseudogeneforward27863972788649Upstream
ABE-0008747ygaQ_3CDSpforward27876422788238Upstream
ABE-0008751ygaQ_4CDSpforward27883772788649Upstream
ABE-0008754glaHCDSforward27889852789962Upstream
ABE-0008756lhgDCDSforward27899822791250Upstream
ABE-0008758gabDCDSforward27912732792721Upstream
ABE-0008760gabTCDSforward27927352794015Matches
ABE-0285535repeat_regionforward27940282794163Downstream
ABE-0008763gabPCDSforward27942532795653Downstream
ABE-0008765glaRCDSforward27956742796336Downstream
ABE-0008767kbpCDScomplement27963372796786Downstream
ABE-0008770yqaECDScomplement27968702797028Downstream
ABE-0008784ygaVCDSforward27972112797510Downstream
ABE-0008786ygaPCDSforward27975202798044Downstream
ABE-0285536repeat_regionforward27980532798082Downstream
ABE-0008788stpACDScomplement27980912798495Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.