Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0008793 (alaE) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0008793 showshow history
Names
alaE ygaW JW2645 ECK2664 b2670
Product
L-alanine exporter
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 2799164 2799613 450 150
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Person Approved ADX-0000978
EnteroFam0008793: Trusted threshold=342.7; Members of this family are defined by searches with an hmm constructed from an alignment of putative orthologous proteins from eight genomes (E. coli MG1655, E. coli EDL933, S. enterica Typhimurium LT2, S. enterica Typhi CT18, Y. pestis CO92, Y. pseudotuberculosis 32953, E. chrysanthemi 3937 and E. carotovora atroseptica SCRI1043). 		Jan 2006
Automated Process Approved IPR010574 (IPR010574 L-alanine exporter AlaE) Apr 2008
Automated Process Approved PF06610 (PF06610 L-alanine exporter) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Uncurated GO cellular component GO:0005886 plasma membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO cellular component GO:0016021 integral component of membrane GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010574
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO molecular function GO:0034639 L-amino acid efflux transmembrane transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010574
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Uncurated name alaE Published Annotation - PubMed ID: 21531828
Reference: Escherichia coli K-12 MG1655 		Sep 2018
Person Approved synonym ECK2664 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW2645 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ygaW Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b2670 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product L-alanine exporter Experimental - PubMed ID: 21531828
Reference: Escherichia coli K-12 MG1655 		Sep 2018
Person Approved alternate product name predicted inner membrane protein Published Annotation - PubMed ID: 16397293 Jan 2006
Person Uncurated alternate product name putative membrane protein Published Annotation - Database Name: GenProtEC Jan 2006
Automated Process Approved alternate product name alanine exporter, alanine-inducible, stress-responsive Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Protein Family
Person Approved EnteroFam EnteroFam0008793: Trusted threshold=342.7; Members of this family are defined by searches with an hmm constructed from an alignment of putative orthologous proteins from eight genomes (E. coli MG1655, E. coli EDL933, S. enterica Typhimurium LT2, S. enterica Typhi CT18, Y. pestis CO92, Y. pseudotuberculosis 32953, E. chrysanthemi 3937 and E. carotovora atroseptica SCRI1043). Protein Sequence Similarity - ASAP FeatureID: ADX-0000978
Reference: EnteroFams 		Jan 2006
Automated Process Approved protein family IPR010574 L-alanine exporter AlaE Protein Sequence Similarity - InterPro Domain: IPR010574
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF06610 L-alanine exporter Protein Sequence Similarity - PFAM Model Name: PF06610
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG13525 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P64550 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:947147 Published Annotation - Entrez Gene Database ID: 947147
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Person Approved db xref UniProtKB:P64550 Published Annotation - Swiss-Prot Accession Number: P64550 Jan 2006
Automated Process Approved db xref GI:1789025 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0008793 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC75717.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Membrane Predicted by PSORTb - PSORTb Final_Score: 9.46
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO cellular component GO:0016021 integral component of membrane GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010574
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO cellular component GO:0005886 plasma membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Uncurated GO molecular function GO:0034639 L-amino acid efflux transmembrane transporter activity GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR010574
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Person Approved Go view EnteroFams ADX-0000978 alaE CDS
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0001701 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002088 ygaW CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002292 alaE CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0003157 ygaW CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002408 alaE CDS
Ortholog
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0003389 CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0000533 CDS
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0003489 alaE CDS
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0004217 alaE CDS
Automated Process Uncurated Go view Dickeya chrysanthemi Ech1591 AFK-0005091 CDS
Person Approved Go view Dickeya dadantii 3937 ABF-0018275 alaE CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0003635 CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0004994 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0002878 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0008762 CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0002657 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0008498 CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0002666 ygaW CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0001627 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0006556 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007365 CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0007315 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0079371 ygaW CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0003050 CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0003559 ygaW CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0009699 CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0009917 CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0003111 ygaW CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0007388 CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0001235 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0007251 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0005771 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0005247 CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0009009 CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0008748 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007449 CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0006541 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007365 CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0008183 CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0008044 CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0008267 CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0009838 CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0027643 ygaW CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0006309 alaE CDS
Automated Process Approved Go view Escherichia coli HS ADR-0007480 CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0001414 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0002508 ygaW CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0002738 ygaW CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0003240 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0003152 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0003084 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0002977 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0177227 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0002975 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0002788 CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0133560 ygaW CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0000818 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0003036 ygaW CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0004251 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0003008 ygaW CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0001368 CDS
Automated Process Uncurated Go view Musicola paradisiaca Ech703 AGA-0005094 CDS
Person Approved Go view Pectobacterium atrosepticum SCRI1043 ABL-0064142 ygaW CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0002178 CDS
Person Uncurated Go view Pectobacterium carotovorum WPP14 ADT-0000978 CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0002195 ygaW CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0008800 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0007082 CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0000175 CDS
Person Approved Go view Salmonella Choleraesuis SC-B67 ADB-0003200 ygaW CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0007361 CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0008643 CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0008198 CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0006607 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0007342 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0008188 CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0006795 CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0008047 CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0006465 CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0007358 CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0005700 CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0002686 CDS
Person Approved Go view Salmonella Paratyphi A ATCC 9150 ADA-0002657 ygaW CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0003494 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0007521 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0007833 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0007019 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0007908 CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0111267 ygaW CDS
Person Approved Go view Salmonella Typhi Ty2 ABS-0084413 ygaW CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0003385 CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0098780 ygaW CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0006503 CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0009023 CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0006726 CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0000150 CDS
Person Approved Go view Shigella boydii 227 ADV-0003131 CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0008624 CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0005593 CDS
Person Approved Go view Shigella dysenteriae 197 ADU-0003275 CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0074046 ygaW CDS
Person Approved Go view Shigella flexneri 301 ABT-0088948 CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0003024 CDS
Person Approved Go view Shigella sonnei 046 ADD-0003084 ygaW CDS
Person Uncurated Go view Vibrio cholerae N16961 ADH-0001902 VC1828 CDS
Automated Process Uncurated Go view Yersinia bercovieri ATCC 43970 [T] AEK-0001557 CDS
Automated Process Uncurated Go view Yersinia enterocolitica 8081 BAH-0002037 CDS
Automated Process Uncurated Go view Yersinia frederiksenii ATCC 33641 [T] AEI-0000205 alaE CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0002616 ygaW CDS
Automated Process Uncurated Go view Yersinia mollaretii ATCC 43969 [T] AEJ-0001611 CDS
Person Approved Go view Yersinia pestis 91001 (biovar Microtus) ACQ-0243065 ygaW CDS
Automated Process Uncurated Go view Yersinia pestis Angola (biovar Pestoides) ADI-0007043 CDS
Automated Process Uncurated Go view Yersinia pestis Antiqua (biovar Antiqua) BAE-0004243 ygaW CDS
Automated Process Uncurated Go view Yersinia pestis B42003004 (biovar Antiqua) BAL-0005964 CDS
Automated Process Uncurated Go view Yersinia pestis CA88-4125 (biovar Orientalis) BAF-0002776 CDS
Person Approved Go view Yersinia pestis CO92 (biovar Orientalis) ABY-0117171 ygaW CDS
Automated Process Uncurated Go view Yersinia pestis E1979001 (biovar Antiqua) BAM-0005161 CDS
Automated Process Uncurated Go view Yersinia pestis FV-1 (biovar Orientalis) BAK-0003876 CDS
Automated Process Uncurated Go view Yersinia pestis IP275 (biovar Orientalis) BAC-0007121 CDS
Automated Process Uncurated Go view Yersinia pestis K1973002 (biovar Mediaevalis) BAO-0007730 CDS
Person Approved Go view Yersinia pestis KIM (biovar Mediaevalis) ABI-0033414 ygaW CDS
Automated Process Uncurated Go view Yersinia pestis MG05-1020 (biovar Orientalis) BAP-0007951 CDS
Automated Process Uncurated Go view Yersinia pestis Nepal516 (biovar Antiqua) BAD-0000514 ygaW CDS
Automated Process Uncurated Go view Yersinia pestis Pestoides F (biovar Pestoides) BAI-0003707 CDS
Automated Process Uncurated Go view Yersinia pestis UG05-0454 (biovar Antiqua) BAN-0007548 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis IP31758 ADS-0007412 CDS
Person Approved Go view Yersinia pseudotuberculosis IP32953 ACZ-0000720 ygaW CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis PB1/+ AFV-0000837 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis YPIII AFW-0004181 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0003202 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0002135 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 2794164 to 2804613
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0008763gabPCDSforward27942532795653Upstream
ABE-0008765glaRCDSforward27956742796336Upstream
ABE-0008767kbpCDScomplement27963372796786Upstream
ABE-0008770yqaECDScomplement27968702797028Upstream
ABE-0008784ygaVCDSforward27972112797510Upstream
ABE-0008786ygaPCDSforward27975202798044Upstream
ABE-0285536repeat_regionforward27980532798082Upstream
ABE-0008788stpACDScomplement27980912798495Upstream
ABE-0008793alaECDSforward27991642799613Matches
ABE-0008795ygaCCDScomplement27996502799994Downstream
ABE-0008799ygaMCDSforward28001462800475Downstream
ABE-0008802nrdHCDSforward28007232800968Downstream
ABE-0008804nrdICDSforward28009652801375Downstream
ABE-0008806nrdECDSforward28013482803492Downstream
ABE-0008808nrdFCDSforward28035022804461Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.