Escherichia coli K-12 MG1655
Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0008948 (hycC) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0008948 showshow history
Names
hycC hevC JW2693 ECK2718 b2723
Product
formate hydrogenlyase subunit
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome complement 2847415 2849241 1827 609
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR003918 (IPR003918 NADH:ubiquinone oxidoreductase) Apr 2008
Automated Process Approved IPR001750 (IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit) Apr 2008
Automated Process Approved PF00361 (PF00361 Proton-conducting membrane transporter) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0006113 fermentation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005886 plasma membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655
Feb 2008
Person Uncurated GO cellular component GO:0019866 organelle inner membrane Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name hycC Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Oct 1998
Person Approved synonym JW2693 Published Annotation - PubMed ID: 16397293 Jan 2006
Automated Process Approved synonym hevC Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Person Approved synonym ECK2718 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b2723 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product formate hydrogenlyase subunit Published Annotation - EcoCyc Accession Number: EG10476
Reference: Escherichia coli K-12 MG1655
Oct 2021
Person Approved alternate product name hydrogenase 3, membrane subunit Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved alternate product name membrane-spanning protein of hydrogenase 3 (part of FHL complex) Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Jan 2006
Person Uncurated alternate product name hydrogenase 3, membrane subunit (part of FHL complex) Published Annotation - Database Name: GenProtEC Jan 2006
Protein Family
Automated Process Approved protein family IPR003918 NADH:ubiquinone oxidoreductase Protein Sequence Similarity - InterPro Domain: IPR003918
Reference: Escherichia coli K-12 MG1655
Apr 2008
Automated Process Approved protein family PF00361 Proton-conducting membrane transporter Protein Sequence Similarity - PFAM Model Name: PF00361
Reference: Escherichia coli K-12 MG1655
Jul 2018
Automated Process Approved protein family IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Protein Sequence Similarity - InterPro Domain: IPR001750
Reference: Escherichia coli K-12 MG1655
Apr 2008
Other
Person Uncurated EC number 1.6.5.- Protein Sequence Similarity - InterPro Domain: IPR003918
Reference: Escherichia coli K-12 MG1655
Dec 2008
Person Uncurated MultiFun 6.1 (cell structure; membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 7.3 (location of gene products; inner membrane) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.3.5 (metabolism; energy metabolism, carbon; fermentation) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved db xref GI:2367154 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Person Approved db xref UniProtKB:P16429 Published Annotation - Swiss-Prot Accession Number: P16429 Jan 2005
Automated Process Approved db xref GeneID:945327 Published Annotation - Entrez Gene Database ID: 945327
Reference: Escherichia coli K-12 MG1655
Jun 2009
Automated Process Approved db xref UniProtKB/Swiss-Prot:P16429 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved db xref ASAP:ABE-0008948 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved db xref EcoGene:EG10476 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Person Approved function enzyme; Energy metabolism, carbon: Fermentation Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655
Oct 1998
Automated Process Approved note membrane-spanning protein of hydrogenase 3 (part of FHL complex); GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006113 - fermentation Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Approved protein id AAC75765.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Membrane Predicted by PSORTb - PSORTb Final_Score: 10.00
Reference: Escherichia coli K-12 MG1655
Feb 2008
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655
Jan 2009
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655
Mar 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655
Feb 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655
Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0006113 fermentation Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO cellular component GO:0019866 organelle inner membrane Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005886 plasma membrane GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655
Feb 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0002655 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002876 hycC CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0001908 hyfB CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0004090 hyfB CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002766 hycC CDS
Ortholog
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0004192 CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0004205 CDS
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0003547 hyfB CDS
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0004275 hyfB CDS
Person Uncurated Go view Enterobacter sp. 638 AEL-0003896 hycC CDS
Automated Process Approved Go view Escherichia albertii TW07627 AFX-0002829 hycC CDS
Automated Process Approved Go view Escherichia coli 101-1 (EAEC) BAB-0008264 hycC CDS
Person Approved Go view Escherichia coli 536 (UPEC) AEF-0002715 hycC CDS
Automated Process Approved Go view Escherichia coli 53638 (EIEC) ADP-0008440 hycC CDS
Person Approved Go view Escherichia coli APEC O1 (APEC) AEG-0002722 hycC CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0001570 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0006497 CDS
Automated Process Approved Go view Escherichia coli B171 (EPEC) ADN-0007426 hycC CDS
Automated Process Approved Go view Escherichia coli B7A (ETEC) ADK-0007013 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0079439 hycC CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0003110 CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0003618 CDS
Automated Process Approved Go view Escherichia coli E110019 (EPEC) ADM-0008157 hycC CDS
Automated Process Approved Go view Escherichia coli E22 (EPEC) ADL-0008827 hycC CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0003181 hycC CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0007448 hycC CDS
Automated Process Approved Go view Escherichia coli EC4024 (EHEC) BBI-0001290 CDS
Automated Process Approved Go view Escherichia coli EC4042 (EHEC) BBA-0007313 hycC CDS
Automated Process Approved Go view Escherichia coli EC4045 (EHEC) BBB-0005834 hycC CDS
Automated Process Approved Go view Escherichia coli EC4076 (EHEC) BAZ-0005309 hycC CDS
Automated Process Approved Go view Escherichia coli EC4113 (EHEC) BAY-0008064 hycC CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0008810 hycC CDS
Automated Process Approved Go view Escherichia coli EC4196 (EHEC) BAX-0007388 hycC CDS
Automated Process Approved Go view Escherichia coli EC4206 (EHEC) BAW-0006604 hycC CDS
Automated Process Approved Go view Escherichia coli EC4401 (EHEC) BAV-0007428 hycC CDS
Automated Process Approved Go view Escherichia coli EC4486 (EHEC) BAU-0008246 hycC CDS
Automated Process Approved Go view Escherichia coli EC4501 (EHEC) BAT-0008463 hycC CDS
Automated Process Approved Go view Escherichia coli EC508 (EHEC) BBJ-0007912 hycC CDS
Automated Process Approved Go view Escherichia coli EC869 (EHEC) BBC-0008281 hycC CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0027701 hycC CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0006368 hyfB CDS
Automated Process Approved Go view Escherichia coli HS ADR-0007534 hycC CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0003197 CDS
Person Approved Go view Escherichia coli K-12 DH10B AEC-0002552 hycC CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0002792 hycC CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0003570 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0003206 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0003137 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0003039 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0177287 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0003028 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0002846 hycC CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0133615 hycC CDS
Automated Process Approved Go view Escherichia coli TW14588 (EHEC) BBK-0000871 CDS
Person Approved Go view Escherichia coli UTI89 (UPEC) AEA-0003095 hycC CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0003069 hycC CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0001393 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0007655 CDS
Automated Process Approved Go view Salmonella Agona SL483 BBX-0007139 hycC CDS
Automated Process Approved Go view Salmonella Arizonae CDC 346-86 BCD-0000124 CDS
Person Approved Go view Salmonella Choleraesuis SC-B67 ADB-0003261 hycC CDS
Automated Process Approved Go view Salmonella Dublin CT_02021853 BCB-0007417 hycC CDS
Automated Process Approved Go view Salmonella Enteritidis P125109 BCF-0008810 hycC CDS
Automated Process Approved Go view Salmonella Gallinarum 287/91 BCG-0008356 hycC CDS
Automated Process Approved Go view Salmonella Hadar RI_05P066 BBT-0006551 hycC CDS
Automated Process Approved Go view Salmonella Heidelberg SL476 BBV-0007398 hycC CDS
Automated Process Approved Go view Salmonella Heidelberg SL486 BBW-0006356 hycC CDS
Automated Process Approved Go view Salmonella Javiana GA_MM04042433 BCA-0005396 hycC CDS
Automated Process Approved Go view Salmonella Kentucky CDC 191 BBZ-0005413 hycC CDS
Automated Process Approved Go view Salmonella Kentucky CVM29188 BBP-0006521 hycC CDS
Automated Process Approved Go view Salmonella Newport SL254 BBQ-0007413 hycC CDS
Automated Process Approved Go view Salmonella Newport SL317 BBR-0005646 hycC CDS
Automated Process Approved Go view Salmonella Paratyphi A AKU_12601 BCH-0002737 CDS
Person Approved Go view Salmonella Paratyphi A ATCC 9150 ADA-0002708 hycC CDS
Automated Process Approved Go view Salmonella Paratyphi B SPB7 BCC-0003560 CDS
Automated Process Approved Go view Salmonella Saintpaul SARA23 BBN-0007577 hycC CDS
Automated Process Approved Go view Salmonella Saintpaul SARA29 BBM-0005647 hycC CDS
Automated Process Approved Go view Salmonella Schwarzengrund CVM19633 BBO-0007075 hycC CDS
Automated Process Approved Go view Salmonella Schwarzengrund SL480 BBY-0005284 hycC CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0111411 hycC CDS
Person Approved Go view Salmonella Typhi Ty2 ABS-0084470 hycC CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0003450 hycC CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0098926 hycC CDS
Automated Process Approved Go view Salmonella Virchow SL491 BBS-0006447 hycC CDS
Automated Process Approved Go view Salmonella Weltevreden SL484 BBU-0006792 hycC CDS
Automated Process Approved Go view Salmonella enterica CVM23701 BBL-0008229 hycC CDS
Person Uncurated Go view Serratia proteamaculans 568 AEN-0008966 hycC CDS
Person Approved Go view Shigella boydii 227 ADV-0003075 hycC CDS
Person Uncurated Go view Shigella boydii BS512 ADJ-0008565 hycC pseudogene
Automated Process Approved Go view Shigella dysenteriae 1012 BAA-0005527 hycC CDS
Person Approved Go view Shigella dysenteriae 197 ADU-0003339 hycC pseudogene
Person Approved Go view Shigella flexneri 2457T ABQ-0074098 hycC pseudogene
Person Approved Go view Shigella flexneri 301 ABT-0088993 hycC pseudogene
Person Approved Go view Shigella flexneri 8401 BAG-0002971 hycC pseudogene
Person Approved Go view Shigella sonnei 046 ADD-0003139 hycC CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)

Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 2842415 to 2854241
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0285541repeat_regionforward28424232842501Downstream
ABE-0008931hycICDScomplement28425732843043Downstream
ABE-0008933hycHCDScomplement28430362843446Downstream
ABE-0008936hycGCDScomplement28434432844210Downstream
ABE-0008942hycFCDScomplement28442102844752Downstream
ABE-0008944hycECDScomplement28447622846471Downstream
ABE-0008946hycDCDScomplement28464892847412Downstream
ABE-0008948hycCCDScomplement28474152849241Matches
ABE-0008950hycBCDScomplement28492382849849Overlaps Upstream
ABE-0008952hycACDScomplement28499742850435Upstream
ABE-0008958hypACDSforward28506472850997Upstream
ABE-0008960hypBCDSforward28510012851873Upstream
ABE-0008962hypCCDSforward28518642852136Upstream
ABE-0008965hypDCDSforward28521362853257Upstream
ABE-0008967hypECDSforward28532542854264Upstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.