Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0011682 (yiaK) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0011682 showshow history
Names
yiaK JW3547 ECK3564 b3575
Product
2,3-diketo-L-gulonate reductase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 3742733 3743731 999 333
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR003767 (IPR003767 Malate/L-lactate dehydrogenase-like) Apr 2008
Automated Process Approved IPR036111 (IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily) Jul 2018
Automated Process Approved PF02615 (PF02615 Malate/L-lactate dehydrogenase) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Approved GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003767
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR003767, IPR036111
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003767
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name yiaK Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym ECK3564 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW3547 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b3575 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product 2,3-diketo-L-gulonate reductase Published Annotation - EcoCyc Accession Number: EG12279
Reference: Escherichia coli K-12 MG1655 		Oct 2021
Person Approved alternate product name putative dehydrogenase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name 2,3-diketo-L-gulonate dehydrogenase, NADH-dependent Published Annotation - Database Name: GenProtEC Jan 2006
Automated Process Approved alternate product name 2,3-diketo-L-gulonate reductase, NADH-dependent Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Protein Family
Automated Process Approved protein family PF02615 Malate/L-lactate dehydrogenase Protein Sequence Similarity - PFAM Model Name: PF02615
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily Protein Sequence Similarity - InterPro Domain: IPR036111
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR003767 Malate/L-lactate dehydrogenase-like Protein Sequence Similarity - InterPro Domain: IPR003767
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Automated Process Approved EC number 1.1.1.- Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved EC number 1.1.1.130 Published Annotation - Swiss-Prot Accession Number: P37672 Feb 2006
Automated Process Uncurated EC number 1.-.-.- Published Annotation - Database Name: EC2GO: GO:0016491
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated MultiFun 1.7.1 (metabolism; central intermediary metabolism; unassigned reversible reactions) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:948096 Published Annotation - Entrez Gene Database ID: 948096
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Person Approved db xref UniProtKB:P37672 Published Annotation - Swiss-Prot Accession Number: P37672 Jan 2005
Automated Process Approved db xref GI:1790000 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG12279 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P37672 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0011682 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function putative enzyme; Not classified Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note putative dehydrogenase Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC76599.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Unknown Predicted by PSORTb - PSORTb Final_Score: 2.00
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Uncurated GO biological process GO:0055114 (OBSOLETE) oxidation-reduction process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR003767, IPR036111
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO biological process GO:0008152 metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003767
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016491 oxidoreductase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003767
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0003893 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0003398 yiaK CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0003347 yiaK CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0003972 yiaK CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0003367 yiaK CDS
Ortholog
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0000702 dlgD CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0000458 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0001444 CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0004728 dlgD CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0003718 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0007496 CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0003636 yiaK CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0000600 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0005475 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0006980 dlgD CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005277 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0080573 yiaK CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0004084 dlgD CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0005057 yiaK CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0006904 dlgD CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0005143 dlgD CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0004071 yiaK CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0008504 dlgD CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0005373 dlgD CDS
Automated Process Approved Go view Escherichia coli HS ADR-0008468 dlgD CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0004283 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0003331 yiaK CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0003790 yiaK CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0004215 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0004229 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0004034 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0004107 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0178253 CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0003923 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0003895 dlgD CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0004126 yiaK CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0000219 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0003613 dlgD CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0000362 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0000386 dlgD CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0004000 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0009633 CDS
Automated Process Uncurated Go view Pantoea stewartii DC283 ACV-0288969 yiaK CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0003142 CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0002299 CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0008909 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0008049 CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0008300 CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0011474 yiaK CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0011505 yiaK CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0005196 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0008349 CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0005698 CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0006104 CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0006899 CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0007444 CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0008301 CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0006544 CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0003556 CDS
Person Uncurated Go view Salmonella Paratyphi A ATCC 9150 ADA-0003518 yiaK CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0004578 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0008473 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0004519 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0007934 CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0004740 CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0113671 CDS
Person Uncurated Go view Salmonella Typhi Ty2 ABS-0085577 CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0004431 yiaK CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0101344 yiaK CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0005543 CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0004969 CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0005267 CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0001781 CDS
Person Approved Go view Shigella boydii 227 ADV-0003910 yiaK CDS
Automated Process Uncurated Go view Shigella boydii BS512 ADJ-0009368 dlgD CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0003153 dlgD CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0075433 yiaK CDS
Person Approved Go view Shigella flexneri 301 ABT-0089842 yiaK CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0004216 yiaK CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0000186 dlgD CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0000509 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB21304mutantTn5 InsertionRequest the StrainABE-0011682yiaKyiaK::Tn5KAN-I-SceI at position 234 in Plus orientation ,+ pKD460Blattner Laboratory
FB21305mutantTn5 InsertionRequest the StrainABE-0011682yiaKyiaK::Tn5KAN-I-SceI at position 234 in Plus orientation ,- pKD465Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 3737733 to 3748731
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0011668malSCDSforward37374973739527Upstream
ABE-0011671avtACDSforward37397053740958Upstream
ABE-0285621repeat_regionforward37409643741061Upstream
ABE-0011674ysaACDScomplement37411093741582Upstream
ABE-0011677plaRCDScomplement37416843742532Upstream
ABE-0011682yiaKCDSforward37427333743731Matches
ABE-0011684yiaLCDSforward37437433744210Downstream
ABE-0011690yiaMCDSforward37443283744801Downstream
ABE-0011692yiaNCDSforward37448043746081Downstream
ABE-0011694yiaOCDSforward37460943747080Downstream
ABE-0011696lyxKCDSforward37470843748580Downstream
ABE-0011698sgbHCDSforward37485773749239Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.