Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0012133 (tnaA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0012133 showshow history
Names
tnaA JW3686 ECK3701 tnaR ind b3708
Product
tryptophanase/L-cysteine desulfhydrase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 3888730 3890145 1416 472
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR001597 (IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase) Apr 2008
Automated Process Approved IPR015421 (IPR015421 Pyridoxal phosphate-dependent transferase, major domain) Apr 2008
Automated Process Approved IPR015424 (IPR015424 Pyridoxal phosphate-dependent transferase) Apr 2008
Automated Process Approved IPR011166 (IPR011166 Beta-eliminating lyase family) Apr 2008
Automated Process Approved IPR013440 (IPR013440 Tryptophanase) Apr 2008
Automated Process Approved PF01212 (PF01212 Beta-eliminating lyase) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Approved GO biological process GO:0006568 tryptophan metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013440
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0009072 aromatic amino acid family metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011166
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0006520 cellular amino acid metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001597
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0009063 cellular amino acid catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0009034 tryptophanase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013440
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016830 carbon-carbon lyase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011166
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0030170 pyridoxal phosphate binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016829 lyase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001597
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name tnaA Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym ind Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved synonym tnaR Published Sequence Analysis - PubMed ID: 9729611 Aug 2003
Person Approved synonym JW3686 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym ECK3701 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b3708 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product tryptophanase/L-cysteine desulfhydrase Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 		Oct 2021
Person Uncurated alternate product name tryptophan deaminase, PLP-dependent Published Annotation - Database Name: GenProtEC Jan 2006
Person Approved alternate product name tryptophanase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Protein Family
Automated Process Approved protein family IPR013440 Tryptophanase Protein Sequence Similarity - InterPro Domain: IPR013440
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF01212 Beta-eliminating lyase Protein Sequence Similarity - PFAM Model Name: PF01212
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR015424 Pyridoxal phosphate-dependent transferase Protein Sequence Similarity - InterPro Domain: IPR015424
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR011166 Beta-eliminating lyase family Protein Sequence Similarity - InterPro Domain: IPR011166
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase Protein Sequence Similarity - InterPro Domain: IPR001597
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR015421 Pyridoxal phosphate-dependent transferase, major domain Protein Sequence Similarity - InterPro Domain: IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Other
Person Approved EC number 4.1.99.1 Published Annotation - Swiss-Prot Accession Number: P0A853 Feb 2006
Automated Process Uncurated EC number 4.-.-.- Published Annotation - Database Name: EC2GO: GO:0016829
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated MultiFun 1.1.3 (metabolism; carbon utilization; amino acids) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG11005 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0012133 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:948221 Published Annotation - Entrez Gene Database ID: 948221
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Automated Process Approved db xref GI:87082323 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P0A853 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved db xref UniProtKB:P0A853 Published Annotation - Swiss-Prot Accession Number: P0A853 Jan 2006
Person Approved function enzyme; Degradation of small molecules: Amino acids Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note tryptophanase; GO_process: GO:0009063 - cellular amino acid catabolic process Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC76731.2 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Approved GO biological process GO:0006568 tryptophan metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013440
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0009063 cellular amino acid catabolic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0006520 cellular amino acid metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001597
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0009072 aromatic amino acid family metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011166
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0030170 pyridoxal phosphate binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0009034 tryptophanase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR013440
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016830 carbon-carbon lyase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011166
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003824 catalytic activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR015421
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0016829 lyase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR001597
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0003994 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0003540 tnaA CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0003119 tnaA CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0007877 tnaA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0003047 tnaA CDS
Ortholog
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0004565 tnaA CDS
Automated Process Uncurated Go view Dickeya chrysanthemi Ech1591 AFK-0005079 CDS
Person Uncurated Go view Dickeya dadantii 3937 ABF-0016682 tnaA CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0003646 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0001599 tnaA CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0004562 tnaA CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0003947 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0007351 tnaA CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0003761 tnaA CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0000466 tnaA CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0010527 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0007668 tnaA CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0005891 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0080816 tnaA CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0004548 tnaA CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0004908 tnaA CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0007612 tnaA CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0007525 tnaA CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0004270 tnaA CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0008648 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0005698 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0008468 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0006983 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0006531 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0006723 tnaA CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0009973 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0004977 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0007785 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0005570 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0005638 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0005502 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0006497 tnaA CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0006854 tnaA CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0028841 tnaA CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0005219 tnaA CDS
Automated Process Approved Go view Escherichia coli HS ADR-0008608 tnaA CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0004148 CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0003453 tnaA CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0003652 tnaA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0004316 tnaA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0004344 tnaA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0004148 tnaA CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0004270 tnaA CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0178399 tnaA CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0004066 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0004072 tnaA CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0134723 tnaA CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0003047 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0004270 tnaA CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0002444 tnaA CDS
Automated Process Uncurated Go view Musicola paradisiaca Ech703 AGA-0005083 CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0003354 tnaA CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0000627 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0000117 tnaA CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0004266 CDS
Automated Process Uncurated Go view Pantoea stewartii DC283 ACV-0286346 tnaA CDS
Person Uncurated Go view Photorhabdus luminescens subsp. laumondii TTO1 [T] ACD-0138578 tnaA CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0009630 tnaA CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0003304 tnaA CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0075282 tnaA CDS
Person Approved Go view Shigella flexneri 301 ABT-0089973 tnaA CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0004043 tnaA CDS
Person Uncurated Go view Vibrio cholerae N16961 ADH-0003050 VCA0161 CDS
Person Uncurated Go view Xenorhabdus nematophila ATCC 19061 [T] ADW-0005306 tnaA CDS
Automated Process Uncurated Go view Yersinia enterocolitica 8081 BAH-0001998 tnaA CDS
Automated Process Uncurated Go view Yersinia frederiksenii ATCC 33641 [T] AEI-0000215 tnaA CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0002626 tnaA CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0004237 tnaA CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 3883730 to 3895145
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0285809ysdDCDSforward38840263884106Upstream
ABE-0012115rpmHCDSforward38843363884476Upstream
ABE-0012117rnpACDSforward38844933884852Upstream
ABE-0285078yidDCDSforward38848163885073Upstream
ABE-0012120yidCCDSforward38850763886722Upstream
ABE-0285633repeat_regionforward38867783886806Upstream
ABE-0012123mnmECDSforward38868283888192Upstream
ABE-0012128tnaCCDSforward38884353888509Upstream
ABE-0012133tnaACDSforward38887303890145Matches
ABE-0012135tnaBCDSforward38902363891483Downstream
ABE-0012139mdtLCDSforward38916153892790Downstream
ABE-0012141yidZCDSforward38927653893724Downstream
ABE-0012144yieECDSforward38938813894630Downstream
ABE-0012146yieFCDSforward38946523895218Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.