Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0013140 (metH) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0013140 showshow history
Names
metH JW3979 ECK4011 b4019
Product
cobalamin-dependent methionine synthase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 4223828 4227511 3684 1228
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Person Approved ADX-0001566
EnteroFam0013140: Trusted threshold=3587.8; Members of this family are defined by searches with an hmm constructed from an alignment of putative orthologous proteins from eight genomes (E. coli MG1655, E. coli EDL933, S. enterica Typhimurium LT2, S. enterica Typhi CT18, Y. pestis CO92, Y. pseudotuberculosis 32953, E. chrysanthemi 3937 and E. carotovora atroseptica SCRI1043). 		Jan 2006
Automated Process Approved IPR000489 (IPR000489 Pterin-binding domain) Apr 2008
Automated Process Approved IPR004223 (IPR004223 Vitamin B12-dependent methionine synthase, activation domain) Apr 2008
Automated Process Approved IPR003726 (IPR003726 Homocysteine-binding domain) Apr 2008
Automated Process Approved IPR006158 (IPR006158 Cobalamin (vitamin B12)-binding domain) Apr 2008
Automated Process Approved IPR011005 (IPR011005 Dihydropteroate synthase-like) Apr 2008
Automated Process Approved IPR011822 (IPR011822 Cobalamin-dependent methionine synthase) Apr 2008
Automated Process Approved IPR003759 (IPR003759 Cobalamin (vitamin B12)-binding module, cap domain) Apr 2008
Automated Process Approved IPR036724 (IPR036724 Cobalamin-binding domain superfamily) Jul 2018
Automated Process Approved IPR036594 (IPR036594 Methionine synthase domain) Jul 2018
Automated Process Approved IPR037010 (IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily) Jul 2018
Automated Process Approved IPR036589 (IPR036589 Homocysteine-binding domain superfamily) Jul 2018
Automated Process Approved PF02607 (PF02607 B12 binding domain) Jul 2018
Automated Process Approved PF02965 (PF02965 Vitamin B12 dependent methionine synthase, activation domain) Jul 2018
Automated Process Approved PF00809 (PF00809 Pterin binding enzyme) Jul 2018
Automated Process Approved PF02574 (PF02574 Homocysteine S-methyltransferase) Jul 2018
Automated Process Approved PF02310 (PF02310 B12 binding domain) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Automated Process Uncurated GO biological process GO:0042558 pteridine-containing compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000489
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Uncurated GO biological process GO:0044237 cellular metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011005
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Approved GO biological process GO:0009086 methionine biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO biological process GO:0009086 methionine biosynthetic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004223
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0009396 folic acid-containing compound biosynthetic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000489
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO biological process GO:0006556 S-adenosylmethionine biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009257 10-formyltetrahydrofolate biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009236 cobalamin biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO cellular component GO:0005622 intracellular anatomical structure GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004223
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO molecular function GO:0050897 cobalt ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011822
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO molecular function GO:0008270 zinc ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011822
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0046872 metal ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006158
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0031419 cobalamin binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006158
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008705 methionine synthase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004223
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003726
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0004156 dihydropteroate synthase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000489
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Automated Process Approved name metH Published Annotation - PubMed ID: 16397293
Reference: Escherichia coli K-12 MG1655 		Sep 2007
Person Approved synonym ECK4011 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved synonym JW3979 Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved locus tag b4019 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product cobalamin-dependent methionine synthase Published Annotation - EcoCyc Accession Number: EG10587
Reference: Escherichia coli K-12 MG1655 		Oct 2021
Person Uncurated alternate product name B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase Published Annotation - Database Name: GenProtEC Jan 2006
Person Approved alternate product name B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Approved alternate product name homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent Published Annotation - PubMed ID: 16397293 Jan 2006
Protein Family
Person Approved EnteroFam EnteroFam0013140: Trusted threshold=3587.8; Members of this family are defined by searches with an hmm constructed from an alignment of putative orthologous proteins from eight genomes (E. coli MG1655, E. coli EDL933, S. enterica Typhimurium LT2, S. enterica Typhi CT18, Y. pestis CO92, Y. pseudotuberculosis 32953, E. chrysanthemi 3937 and E. carotovora atroseptica SCRI1043). Protein Sequence Similarity - ASAP FeatureID: ADX-0001566
Reference: EnteroFams 		Jan 2006
Automated Process Approved protein family IPR004223 Vitamin B12-dependent methionine synthase, activation domain Protein Sequence Similarity - InterPro Domain: IPR004223
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR000489 Pterin-binding domain Protein Sequence Similarity - InterPro Domain: IPR000489
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR006158 Cobalamin (vitamin B12)-binding domain Protein Sequence Similarity - InterPro Domain: IPR006158
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR003726 Homocysteine-binding domain Protein Sequence Similarity - InterPro Domain: IPR003726
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family PF02965 Vitamin B12 dependent methionine synthase, activation domain Protein Sequence Similarity - PFAM Model Name: PF02965
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF02607 B12 binding domain Protein Sequence Similarity - PFAM Model Name: PF02607
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF00809 Pterin binding enzyme Protein Sequence Similarity - PFAM Model Name: PF00809
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF02574 Homocysteine S-methyltransferase Protein Sequence Similarity - PFAM Model Name: PF02574
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF02310 B12 binding domain Protein Sequence Similarity - PFAM Model Name: PF02310
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR011005 Dihydropteroate synthase-like Protein Sequence Similarity - InterPro Domain: IPR011005
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR036589 Homocysteine-binding domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036589
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily Protein Sequence Similarity - InterPro Domain: IPR037010
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Protein Sequence Similarity - InterPro Domain: IPR003759
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR011822 Cobalamin-dependent methionine synthase Protein Sequence Similarity - InterPro Domain: IPR011822
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR036724 Cobalamin-binding domain superfamily Protein Sequence Similarity - InterPro Domain: IPR036724
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family IPR036594 Methionine synthase domain Protein Sequence Similarity - InterPro Domain: IPR036594
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Person Approved EC number 2.1.1.13 Published Annotation - Swiss-Prot Accession Number: P13009 Feb 2006
Person Uncurated MultiFun 1.7.17 (metabolism; central intermediary metabolism; formyl-tetrahydrofolate biosynthesis) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.7.20 (metabolism; central intermediary metabolism; S-adenosyl methionine biosynthesis) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.5.3.13 (metabolism; building block biosynthesis; cofactor, small molecule carrier; cobalamin (Vitamin B12)) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.5.1.9 (metabolism; building block biosynthesis; amino acids; methionine) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:948522 Published Annotation - Entrez Gene Database ID: 948522
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Person Approved db xref UniProtKB:P13009 Published Annotation - Swiss-Prot Accession Number: P13009 Jan 2005
Automated Process Approved db xref UniProtKB/Swiss-Prot:P13009 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GI:1790450 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref ASAP:ABE-0013140 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG10587 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Amino acid biosynthesis: Methionine Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF; GO_process: GO:0009086 - methionine biosynthetic process; GO_process: GO:0006556 - S-adenosylmethionine biosynthetic process Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC76989.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Cytoplasmic Predicted by PSORTb - PSORTb Final_Score: 8.96
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iMC1010 Experimental - PubMed ID: 15129285
Reference: Escherichia coli K-12 MG1655 		Mar 2009
Person Uncurated subsystem component of in silico model iJR904 Experimental - PubMed ID: 12952533
Reference: Escherichia coli K-12 MG1655 		Feb 2009
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Automated Process Approved GO biological process GO:0009396 folic acid-containing compound biosynthetic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000489
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO biological process GO:0009086 methionine biosynthetic process GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004223
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO biological process GO:0042558 pteridine-containing compound metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR000489
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated GO biological process GO:0009236 cobalamin biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Approved GO biological process GO:0009086 methionine biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO biological process GO:0009257 10-formyltetrahydrofolate biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO biological process GO:0044237 cellular metabolic process GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011005
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Person Uncurated GO biological process GO:0006556 S-adenosylmethionine biosynthetic process Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Uncurated GO cellular component GO:0005737 cytoplasm GO Inferred from Electronic Annotation - PubMed ID: 15501914
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Automated Process Approved GO cellular component GO:0005622 intracellular anatomical structure GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004223
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Uncurated GO molecular function GO:0008270 zinc ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: InterPro2GO: IPR011822
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved GO molecular function GO:0046872 metal ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006158
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0050897 cobalt ion binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR011822
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0031419 cobalamin binding GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR006158
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR003726
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0008705 methionine synthase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR004223
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0004156 dihydropteroate synthase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR000489
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Person Approved Go view EnteroFams ADX-0001566 metH CDS
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0001604 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0001732 metH CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0001645 metH CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0001627 metH CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0001722 metH CDS
Ortholog
Automated Process Uncurated Go view Brenneria salicis ATCC 15712 [T] AMK-0000462 CDS
Automated Process Uncurated Go view Brenneria sp. EniD312 AKG-0003551 CDS
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0000285 metH CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0003935 metH CDS
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0004225 metH CDS
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0000258 metH CDS
Automated Process Uncurated Go view Dickeya chrysanthemi Ech1591 AFK-0004810 CDS
Person Approved Go view Dickeya dadantii 3937 ABF-0017820 metH CDS
Automated Process Uncurated Go view Dickeya parazeae Ech586 AGC-0003789 CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0000533 metH CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0001923 metH CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0006250 metH CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0004279 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0006963 metH CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0004074 metH CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0004823 metH CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0010187 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0006154 metH CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0007741 CDS
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0081184 metH CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0004667 metH CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0004396 metH CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0006096 metH CDS
Automated Process Uncurated Go view Escherichia coli E22 (EPEC) ADL-0006552 metH CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0004612 metH CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0009000 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0003044 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0008817 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0007330 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0006977 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0008961 metH CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0010319 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0006992 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0008135 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007106 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0005686 metH CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0006456 metH CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0006099 metH CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0004956 metH CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0029186 metH CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0006958 metH CDS
Automated Process Approved Go view Escherichia coli HS ADR-0008943 metH CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0004595 metH CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0003715 metH CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0004105 metH CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0004847 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0004713 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0004662 CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0178745 metH CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0004404 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0004464 metH CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0135049 metH CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0003252 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0004586 metH CDS
Automated Process Uncurated Go view Ewingella americana ATCC 33852 [T] AMA-0003320 metH CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0001065 metH CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0004449 metH CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0002647 metH CDS
Automated Process Uncurated Go view Musicola paradisiaca Ech703 AGA-0004874 CDS
Automated Process Uncurated Go view Pantoea agglomerans IG1 APM-0003349 CDS
Automated Process Uncurated Go view Pantoea agglomerans SL1-M5 ALY-0002388 metH CDS
Automated Process Uncurated Go view Pantoea ananatis AJ13355 AOV-0003495 metH CDS
Automated Process Uncurated Go view Pantoea ananatis B1-9 APL-0000495 CDS
Automated Process Uncurated Go view Pantoea ananatis LMG 20103 AKB-0000262 metH CDS
Automated Process Uncurated Go view Pantoea ananatis PA13 APK-0004121 CDS
Automated Process Uncurated Go view Pantoea sp. At-9b AGM-0007998 CDS
Automated Process Uncurated Go view Pantoea sp. aB AJV-0003763 CDS
Automated Process Uncurated Go view Pantoea vagans C9-1 ALK-0007250 metH CDS
Person Approved Go view Pectobacterium atrosepticum SCRI1043 ABL-0064306 metH CDS
Automated Process Uncurated Go view Pectobacterium brasiliensis 1692 AED-0002296 metH CDS
Person Uncurated Go view Pectobacterium carotovorum WPP14 ADT-0001038 metH CDS
Automated Process Uncurated Go view Pectobacterium parmentieri WPP163 AFJ-0002977 metH CDS
Automated Process Uncurated Go view Pectobacterium sp. PC1 AFL-0009017 CDS
Person Uncurated Go view Pseudomonas syringae pv. tomato DC3000 ADG-0002779 metH CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0008597 metH CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0003628 CDS
Person Approved Go view Salmonella Choleraesuis SC-B67 ADB-0004788 metH CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0008838 metH CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0013132 metH CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0012409 metH CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0007917 metH CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0008878 metH CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0007283 metH CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0003944 metH CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0005662 metH CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0007987 metH CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0008871 metH CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0008175 metH CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0004062 CDS
Person Approved Go view Salmonella Paratyphi A ATCC 9150 ADA-0004021 metH CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0005207 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0004221 metH CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0007728 metH CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0008465 metH CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0008478 metH CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0114328 metH CDS
Person Approved Go view Salmonella Typhi Ty2 ABS-0085842 metH CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0005041 metH CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0102885 metH CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0004966 metH CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0007609 metH CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0005700 metH CDS
Automated Process Uncurated Go view Serratia marcescens subsp. marcescens ATCC 13880 [T] AMF-0001346 metH CDS
Person Uncurated Go view Shewanella oneidensis MR-1 ACY-0264585 metH CDS
Person Approved Go view Shigella boydii 227 ADV-0004397 metH CDS
Person Uncurated Go view Shigella dysenteriae 197 ADU-0004882 metH CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0074867 metH CDS
Person Approved Go view Shigella flexneri 301 ABT-0090300 metH CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0004345 metH CDS
Person Approved Go view Shigella sonnei 046 ADD-0004555 metH CDS
Person Uncurated Go view Trabulsiella guamensis ATCC 49490 [T] APH-0003113 metH CDS
Person Uncurated Go view Vibrio cholerae N16961 ADH-0000429 VC0390 CDS
Automated Process Uncurated Go view Yersinia bercovieri ATCC 43970 [T] AEK-0002275 CDS
Automated Process Uncurated Go view Yersinia enterocolitica 8081 BAH-0011139 metH CDS
Automated Process Uncurated Go view Yersinia frederiksenii ATCC 33641 [T] AEI-0003376 metH CDS
Automated Process Uncurated Go view Yersinia intermedia ATCC 29909 [T] AEH-0003066 metH CDS
Automated Process Uncurated Go view Yersinia mollaretii ATCC 43969 [T] AEJ-0003543 CDS
Person Approved Go view Yersinia pestis 91001 (biovar Microtus) ACQ-0241689 metH CDS
Automated Process Uncurated Go view Yersinia pestis Angola (biovar Pestoides) ADI-0008047 metH CDS
Automated Process Uncurated Go view Yersinia pestis Antiqua (biovar Antiqua) BAE-0000028 metH CDS
Automated Process Uncurated Go view Yersinia pestis B42003004 (biovar Antiqua) BAL-0007513 metH CDS
Automated Process Uncurated Go view Yersinia pestis CA88-4125 (biovar Orientalis) BAF-0003651 metH CDS
Person Approved Go view Yersinia pestis CO92 (biovar Orientalis) ABY-0127790 metH CDS
Automated Process Uncurated Go view Yersinia pestis E1979001 (biovar Antiqua) BAM-0008537 metH CDS
Automated Process Uncurated Go view Yersinia pestis F1991016 (biovar Orientalis) BAQ-0008268 metH CDS
Automated Process Uncurated Go view Yersinia pestis IP275 (biovar Orientalis) BAC-0009196 metH CDS
Automated Process Uncurated Go view Yersinia pestis K1973002 (biovar Mediaevalis) BAO-0008234 metH CDS
Person Approved Go view Yersinia pestis KIM (biovar Mediaevalis) ABI-0029603 metH CDS
Automated Process Uncurated Go view Yersinia pestis MG05-1020 (biovar Orientalis) BAP-0006287 metH CDS
Automated Process Uncurated Go view Yersinia pestis Nepal516 (biovar Antiqua) BAD-0000025 metH CDS
Automated Process Uncurated Go view Yersinia pestis Pestoides F (biovar Pestoides) BAI-0000206 CDS
Automated Process Uncurated Go view Yersinia pestis UG05-0454 (biovar Antiqua) BAN-0007511 metH CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis IP31758 ADS-0004237 metH CDS
Person Approved Go view Yersinia pseudotuberculosis IP32953 ACZ-0003765 metH CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis PB1/+ AFV-0004575 CDS
Automated Process Uncurated Go view Yersinia pseudotuberculosis YPIII AFW-0000429 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0000494 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0000608 metH CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB21609mutantTn5 InsertionRequest the StrainABE-0013140metHmetH::Tn5KAN-I-SceI at position 1935 in Minus orientation ,+ pKD460Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 4218828 to 4232511
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0013131aceKCDSforward42185964220332Upstream
ABE-0285846aceK-intncRNAforward42188794218963Upstream
ABE-0013133arpACDScomplement42203014222487Upstream
ABE-0013136iclRCDScomplement42228044223628Upstream
ABE-0013140metHCDSforward42238284227511Matches
ABE-0013143yjbBCDSforward42277314229362Downstream
ABE-0285665repeat_regionforward42293764229445Downstream
ABE-0013146pepECDScomplement42294534230142Downstream
ABE-0013150rluFCDSforward42303544231226Downstream
ABE-0013153yjbDCDScomplement42313594231631Downstream
ABE-0013156lysCCDScomplement42318844233233Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.