Escherichia coli K-12 MG1655
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Working With: Genome: Escherichia coli K-12 MG1655 Version: v3

ABE-0013283 (aphA) - Escherichia coli K-12 MG1655 - Feature Annotation

ASAP ID
ABE-0013283 showshow history
Names
aphA napA yjbP hobH JW4015 ECK4047 b4055
Product
acid phosphatase/phosphotransferase
Type
CDS
Location
# Contig Strand Left Right Length (b.p.) Length (a.a.)
1 Chromosome forward 4269414 4270127 714 238
Sequence

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Context

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Protein Families to toptop
Author Approval Family Annotated
Automated Process Approved IPR010025 (IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA) Apr 2008
Automated Process Approved IPR005519 (IPR005519 Acid phosphatase, class B-like) Apr 2008
Automated Process Approved IPR036412 (IPR036412 HAD-like superfamily) Jul 2018
Automated Process Approved PF03767 (PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase)) Jul 2018
Gene Ontology to toptop
Author Approval Type Annotation Evidence Annotated
Person Uncurated GO biological process GO:0015949 nucleobase-containing small molecule interconversion Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO cellular component GO:0030288 outer membrane-bounded periplasmic space GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010025
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Person Uncurated GO cellular component GO:0005737 cytoplasm Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO molecular function GO:0003993 acid phosphatase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010025
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Annotations to toptop
Author Approval Type Annotation Evidence Annotated
Nomenclature
Person Approved name aphA Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Person Approved synonym JW4015 Published Annotation - PubMed ID: 16397293 Jan 2006
Automated Process Approved synonym hobH Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved synonym napA Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved synonym ECK4047 Published Annotation - PubMed ID: 16397293 Jan 2006
Automated Process Approved synonym yjbP Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved locus tag b4055 Unique Identifier - Origin: Guy Plunkett III, guy@genome.wisc.edu May 2004
Product
Person Uncurated product acid phosphatase/phosphotransferase Published Annotation - EcoCyc Accession Number: EG11934
Reference: Escherichia coli K-12 MG1655 		Oct 2021
Person Approved alternate product name acid phosphatase/phosphotransferase, class B, non-specific Published Annotation - PubMed ID: 16397293 Jan 2006
Person Approved alternate product name diadenosine tetraphosphatase Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Jan 2006
Person Uncurated alternate product name non-specific acid phosphatase/phosphotransferase, class B Published Annotation - Database Name: GenProtEC Jan 2006
Protein Family
Automated Process Approved protein family IPR005519 Acid phosphatase, class B-like Protein Sequence Similarity - InterPro Domain: IPR005519
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA Protein Sequence Similarity - InterPro Domain: IPR010025
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved protein family IPR036412 HAD-like superfamily Protein Sequence Similarity - InterPro Domain: IPR036412
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Automated Process Approved protein family PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) Protein Sequence Similarity - PFAM Model Name: PF03767
Reference: Escherichia coli K-12 MG1655 		Jul 2018
Other
Person Approved EC number 3.1.3.2 Published Annotation - Swiss-Prot Accession Number: P0AE22 Feb 2006
Person Uncurated MultiFun 7.1 (location of gene products; cytoplasm) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Person Uncurated MultiFun 1.7.33 (metabolism; central intermediary metabolism; nucleotide and nucleoside conversions) Published Annotation - MultiFun Database Name: MultiFun Feb 2002
Automated Process Approved codon start 1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref EcoGene:EG11934 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref UniProtKB/Swiss-Prot:P0AE22 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GeneID:948562 Published Annotation - Entrez Gene Database ID: 948562
Reference: Escherichia coli K-12 MG1655 		Jun 2009
Person Approved db xref UniProtKB:P0AE22 Published Annotation - Swiss-Prot Accession Number: P0AE22 Jan 2006
Automated Process Approved db xref ASAP:ABE-0013283 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved db xref GI:2367341 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Person Approved function enzyme; Central intermediary metabolism: Nucleotide hydrolysis Published Annotation - GenBank Accession Number: U00096
Reference: Escherichia coli MG1655 		Oct 1998
Automated Process Approved note diadenosine tetraphosphatase; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0015949 - nucleobase, nucleoside and nucleotide interconversion Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Approved protein id AAC77025.1 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Automated Process Uncurated subcellular localization Unknown Predicted by PSORTb - PSORTb Final_Score: 2.50
Reference: Escherichia coli K-12 MG1655 		Feb 2008
Person Uncurated subsystem component of in silico model iAF1260 Experimental - PubMed ID: 17593909
Reference: Escherichia coli K-12 MG1655 		Jan 2009
Automated Process Approved transl table 11 Published Annotation - GenBank Accession Number: U00096.3
Reference: Escherichia coli K-12 MG1655 		Oct 2013
Gene Ontology
Person Uncurated GO biological process GO:0015949 nucleobase-containing small molecule interconversion Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Person Uncurated GO cellular component GO:0005737 cytoplasm Ontology Mapping - Source and Dest Ontology: MultiFun to GO Mar 2004
Automated Process Approved GO cellular component GO:0030288 outer membrane-bounded periplasmic space GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010025
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Automated Process Approved GO molecular function GO:0003993 acid phosphatase activity GO Inferred from Electronic Annotation - Database Name:Identifier: INTERPRO:IPR010025
Reference: Escherichia coli K-12 MG1655 		Apr 2008
Comparative to toptop
Author Approval Details Genome Feature Name Type
Member
Automated Process Uncurated Go view OrthoMCL (14 enterobacteria) AMM-0005246 CDS
Automated Process Uncurated Go view OrthoMCL (205 gammaproteobacteria) APP-0002769 aphA CDS
Automated Process Uncurated Go view OrthoMCL (307 Enterobacteriaceae) ATM-0002794 aphA CDS
Automated Process Uncurated Go view OrthoMCL (42 Serratia) BEZ-0009155 aphA CDS
Automated Process Uncurated Go view OrthoMCL (UW draft) CQJ-0002606 aphA CDS
Ortholog
Automated Process Uncurated Go view Buttiauxella agrestis ATCC 33320 [T] APC-0000316 aphA CDS
Automated Process Uncurated Go view Cedecea davisae ATCC 33431 [T] ALZ-0003902 CDS
Automated Process Approved Go view Citrobacter amalonaticus ATCC 25405 [T] AUW-0004169 aphA CDS
Automated Process Approved Go view Citrobacter freundii ATCC 8090 [T] AVI-0000205 aphA CDS
Automated Process Uncurated Go view Enterobacter cloacae subsp. cloacae ATCC 13047 [T] (AToL DRAFT) AMB-0000574 CDS
Automated Process Uncurated Go view Escherichia albertii TW07627 AFX-0001978 aphA CDS
Automated Process Uncurated Go view Escherichia coli 101-1 (EAEC) BAB-0006332 aphA CDS
Automated Process Approved Go view Escherichia coli 536 (UPEC) AEF-0004334 CDS
Automated Process Uncurated Go view Escherichia coli 53638 (EIEC) ADP-0006917 CDS
Automated Process Approved Go view Escherichia coli APEC O1 (APEC) AEG-0004131 aphA CDS
Automated Process Approved Go view Escherichia coli ATCC 11775 [T] AMC-0004762 CDS
Automated Process Approved Go view Escherichia coli ATCC 8739 AEM-0010138 CDS
Automated Process Uncurated Go view Escherichia coli B171 (EPEC) ADN-0006262 aphA CDS
Automated Process Uncurated Go view Escherichia coli B7A (ETEC) ADK-0009244 pseudogene
Person Approved Go view Escherichia coli CFT073 (UPEC) ABR-0081253 aphA CDS
Automated Process Uncurated Go view Escherichia coli DEC7E (UM-IGS draft) CFX-0004720 aphA CDS
Automated Process Uncurated Go view Escherichia coli DEC9A (UM-IGS draft) CFY-0005321 aphA CDS
Automated Process Uncurated Go view Escherichia coli E110019 (EPEC) ADM-0006143 aphA CDS
Automated Process Approved Go view Escherichia coli E2348/69 (EPEC) BCI-0004675 aphA CDS
Automated Process Approved Go view Escherichia coli E24377A (ETEC) ADO-0009044 aphA CDS
Automated Process Uncurated Go view Escherichia coli EC4024 (EHEC) BBI-0003110 CDS
Automated Process Uncurated Go view Escherichia coli EC4042 (EHEC) BBA-0008886 CDS
Automated Process Uncurated Go view Escherichia coli EC4045 (EHEC) BBB-0007399 CDS
Automated Process Uncurated Go view Escherichia coli EC4076 (EHEC) BAZ-0007044 aphA CDS
Automated Process Uncurated Go view Escherichia coli EC4113 (EHEC) BAY-0006279 aphA CDS
Automated Process Approved Go view Escherichia coli EC4115 (EHEC) BAS-0010388 CDS
Automated Process Uncurated Go view Escherichia coli EC4196 (EHEC) BAX-0007060 aphA CDS
Automated Process Uncurated Go view Escherichia coli EC4206 (EHEC) BAW-0008204 CDS
Automated Process Uncurated Go view Escherichia coli EC4401 (EHEC) BAV-0007174 aphA CDS
Automated Process Uncurated Go view Escherichia coli EC4486 (EHEC) BAU-0005756 aphA CDS
Automated Process Uncurated Go view Escherichia coli EC4501 (EHEC) BAT-0006503 aphA CDS
Automated Process Uncurated Go view Escherichia coli EC508 (EHEC) BBJ-0006030 aphA CDS
Automated Process Uncurated Go view Escherichia coli EC869 (EHEC) BBC-0005025 aphA CDS
Person Approved Go view Escherichia coli EDL933 (EHEC) ABH-0029229 aphA CDS
Automated Process Approved Go view Escherichia coli F11 (UPEC) ADQ-0007017 aphA CDS
Automated Process Uncurated Go view Escherichia coli J96 (UPEC) CQK-0004656 aphA CDS
Person Uncurated Go view Escherichia coli K-12 DH10B AEC-0003751 aphA CDS
Person Approved Go view Escherichia coli K-12 W3110 ADY-0004141 aphA CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR68 CGA-0004804 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR71 CGB-0004765 CDS
Automated Process Uncurated Go view Escherichia coli MOD1-ECOR8 CFZ-0004621 CDS
Automated Process Uncurated Go view Escherichia coli Nissle 1917 AML-0004697 aphA CDS
Automated Process Uncurated Go view Escherichia coli RS218 (NMEC) ACK-0178867 aphA CDS
Automated Process Approved Go view Escherichia coli SE11 AFS-0004449 CDS
Automated Process Approved Go view Escherichia coli SMS-3-5 AFT-0004509 aphA CDS
Person Approved Go view Escherichia coli Sakai (EHEC) ACA-0135149 aphA CDS
Automated Process Uncurated Go view Escherichia coli TW14588 (EHEC) BBK-0003300 CDS
Automated Process Approved Go view Escherichia coli UTI89 (UPEC) AEA-0004650 aphA CDS
Automated Process Uncurated Go view Ewingella americana ATCC 33852 [T] AMA-0000830 CDS
Person Uncurated Go view Hafnia alvei ATCC 13337 [T] AMD-0003202 CDS
Person Uncurated Go view Klebsiella pneumoniae subsp. pneumoniae MGH 78578 AEP-0004492 aphA CDS
Automated Process Uncurated Go view Leclercia adecarboxylata ATCC 23216 [T] AME-0002683 CDS
Automated Process Uncurated Go view Salmonella Agona SL483 BBX-0008668 aphA CDS
Automated Process Uncurated Go view Salmonella Arizonae CDC 346-86 BCD-0003589 CDS
Person Approved Go view Salmonella Choleraesuis SC-B67 ADB-0004861 aphA CDS
Automated Process Uncurated Go view Salmonella Dublin CT_02021853 BCB-0008883 aphA CDS
Automated Process Uncurated Go view Salmonella Enteritidis P125109 BCF-0013273 aphA CDS
Automated Process Uncurated Go view Salmonella Gallinarum 287/91 BCG-0012541 aphA CDS
Automated Process Uncurated Go view Salmonella Hadar RI_05P066 BBT-0007850 aphA CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL476 BBV-0008947 aphA CDS
Automated Process Uncurated Go view Salmonella Heidelberg SL486 BBW-0007351 aphA CDS
Automated Process Uncurated Go view Salmonella Javiana GA_MM04042433 BCA-0003986 aphA CDS
Automated Process Uncurated Go view Salmonella Kentucky CDC 191 BBZ-0005727 aphA CDS
Automated Process Uncurated Go view Salmonella Kentucky CVM29188 BBP-0008054 aphA CDS
Automated Process Uncurated Go view Salmonella Newport SL254 BBQ-0008938 aphA CDS
Automated Process Uncurated Go view Salmonella Newport SL317 BBR-0008244 aphA CDS
Automated Process Uncurated Go view Salmonella Paratyphi A AKU_12601 BCH-0004102 CDS
Person Approved Go view Salmonella Paratyphi A ATCC 9150 ADA-0004061 aphA CDS
Automated Process Uncurated Go view Salmonella Paratyphi B SPB7 BCC-0005259 CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA23 BBN-0004288 aphA CDS
Automated Process Uncurated Go view Salmonella Saintpaul SARA29 BBM-0007683 aphA CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund CVM19633 BBO-0008561 aphA CDS
Automated Process Uncurated Go view Salmonella Schwarzengrund SL480 BBY-0006252 aphA CDS
Person Approved Go view Salmonella Typhi CT18 ABX-0114412 aphA CDS
Person Approved Go view Salmonella Typhi Ty2 ABS-0085882 aphA CDS
Automated Process Uncurated Go view Salmonella Typhimurium 14028S AJR-0005113 aphA CDS
Person Approved Go view Salmonella Typhimurium LT2 [T] ABU-0103077 aphA CDS
Automated Process Uncurated Go view Salmonella Virchow SL491 BBS-0004899 aphA CDS
Automated Process Uncurated Go view Salmonella Weltevreden SL484 BBU-0007568 aphA CDS
Automated Process Uncurated Go view Salmonella enterica CVM23701 BBL-0005767 aphA CDS
Person Approved Go view Shigella boydii 227 ADV-0004443 aphA CDS
Automated Process Approved Go view Shigella boydii BS512 ADJ-0009988 aphA CDS
Automated Process Uncurated Go view Shigella dysenteriae 1012 BAA-0004615 aphA CDS
Person Approved Go view Shigella flexneri 2457T ABQ-0074789 aphA CDS
Person Approved Go view Shigella flexneri 301 ABT-0090361 aphA CDS
Automated Process Approved Go view Shigella flexneri 8401 BAG-0004417 aphA CDS
Person Approved Go view Shigella sonnei 046 ADD-0004600 aphA CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 43003 APO-0000665 CDS
Automated Process Uncurated Go view Yokenella regensburgei ATCC 49455 [T] AMG-0000571 CDS
Experimental to toptop
SelectSetNameSetDetailsNotes
stringent responsetranscriptional profile of the stringent responseNone
Recombinant heat-shock dataexpression data for recombinant strain under heat shockThese data are from the Harcum laboratory. (Jeremy Glasner)
Suppressor tRNA expressionexperiment comparing transcript levels in cells with and without suppressor tRNA expressionThese data were reported in the paper: Herring and Blattner. 2004. Global transcriptional effects of a suppressor tRNA and the inactivation of the regulator frmR. J. Bacteriol. 186(20):6714-20. Link to Abstract (Jeremy Glasner)
Recombinant E. coli expressionexperiment comparing expression of wild-type E. coli with the same strain harboring a plasmid that expresses protein when induced with IPTG These data were reported in the paper: F. T. Haddadin, S. W. Harcum (2005) Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli, Biotechnology and Bioengineering, 90:127-153. Link to Abstract (Jeremy Glasner)
Aerobic shiftAerobic shiftThese data were reported in the paper: Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. 2004. Integrating high-throughput and computational data elucidates bacterial networks. Nature. 2004 May 6;429(6987):92-6. Link to Abstract (Jeremy Glasner)
CalibratorCalibrated microarray experiments (50 hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
AffyData1Affymetrix Experiments (data from 41 chip hybridizations)This data was used in the paper: Allen et al., J. Bacteriol. 185(21):6392-9 (Jeremy Glasner)
Strains to toptop

Strains with mutations in this feature.

Strain NameStrain TypeStrain InformationStrain RequestFeatureIDNameMutation DetailsExperiments Using StrainSubmitter
FB21634mutantTn5 InsertionRequest the StrainABE-0013283aphAaphA::Tn5KAN-I-SceI at position 416 in Plus orientation ,+ pKD460Blattner Laboratory
Context Table to toptop

Listed below are features that lie nearby this feature. Features encoded in multiple intervals may appear more than once in the table. Features that span the origin will have a left endpoint greater than the right endpoint.

Features overlapping the region 4264414 to 4275127
FeatureIDNameFeature TypeStrandLeft EndRight EndRelationship
ABE-0000001sourceforward14641652Contains
ABE-0013269dnaBCDSforward42643144265729Upstream
ABE-0013272alrCDSforward42657824266861Upstream
ABE-0285671repeat_regionforward42668884266984Upstream
ABE-0013278tyrBCDSforward42671144268307Upstream
ABE-0285672repeat_regionforward42683174268340Upstream
ABE-0285200yjbSCDScomplement42688094269012Upstream
ABE-0013283aphACDSforward42694144270127Matches
ABE-0013286yjbQCDSforward42702384270654Downstream
ABE-0013288yjbRCDSforward42706584271014Downstream
ABE-0013290uvrACDScomplement42710494273871Downstream
ABE-0013298ssbCDSforward42741254274661Downstream
ABE-0013300yjcBCDScomplement42747604275041Downstream
Release Notes to toptop
All MG1655 annotations and sequence data are publicly available, and investigators can use these data in publications without contacting the genome curators. This version of the sequence was the source of GenBank record U00096.3. Ongoing annotation updates to that GenBank record are being generated from a collaboration that includes ASAP, EcoGene, the Coli Genetic Stock Center, EcoliHub, EcoCyc, RegulonDB and UniProtKB/Swiss-Prot.