The coding region has been updated to extend the N-terminus to one that is more supported by the available transcript and conservation data. The update initiates translation at a CUG start codon that is very well-conserved and is in a strong Kozak signal context. This non-AUG start codon is supported by experimental evidence for the rat homolog in PMID:15635094. The update adds a predicted N-terminal signal peptide to the protein.
Red highlighting indicates amino acids encoded across a splice junction.
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair. This works on the replacement symbol in the Translation Exceptions section also.
Translation Exceptions: replace the symbol L (codon CTG) with M at amino acid position 1