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Report for CCDS43420.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
43420.2 Public Homo sapiens 6 ECI2 24 110 108 CCDS HistoryNCBI Gene:10455Re-query CCDS DB by CCDS ID:43420.2Re-query CCDS DB by GeneID:10455See the combined annotation on chromosome 6 in Sequence Viewer

Public Note for CCDS 43420.1
The coding region has been updated to represent an alternative splicing pattern, and to extend the N-terminus to one that is better supported by the available transcript data. The annotated translational start codon is specific to human, but it has a strong Kozak signal and is thus likely to be used. An alternative and better conserved start codon, which also has a strong Kozak signal, exists further downstream; initiation from that start codon would result in a protein that is 2 aa shorter at the N-terminus. No experimental evidence exists to indicate which start codon is preferentially used in vivo.

Public since: CCDS release 5, NCBI annotation release 36.3, Ensembl annotation release 47

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 43420.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000380118.8 ENSP00000369461.3 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000380118.8Link to Ensembl Protein Viewer:ENSP00000369461.3Re-query CCDS DB by Nucleotide ID:ENST00000380118Re-query CCDS DB by Protein ID:ENSP00000369461
Original member Current member NCBI NM_206836.3 NP_996667.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_206836.3Link to Protein Sequence:NP_996667.2Re-query CCDS DB by Nucleotide ID:NM_206836Re-query CCDS DB by Protein ID:NP_996667Link to BLAST:NP_996667.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_996667.2 394 O75521-1 394 100% 0 0

Chromosomal Locations for CCDS 43420.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 6 (NC_000006.12)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6See the combined annotation on chromosome 6 in Sequence Viewer

Chromosome Start Stop Links
6 4115874 4116029 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4117308 4117451 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4119186 4119275 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4125250 4125370 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4126135 4126237 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4127762 4127831 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4130372 4130560 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4130767 4130865 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4133549 4133711 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6
6 4135511 4135560 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 6Link to Ensembl Genome Browser on chromosome 6

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1185 nt):
ATGGCGATGGCGTACTTGGCTTGGAGACTGGCGCGGCGTTCGTGTCCGAGTTCTCTGCAGGTCACTAGTT
TCCCGGTAGTTCAGCTGCACATGAATAGAACAGCAATGAGAGCCAGTCAGAAGGACTTTGAAAATTCAAT
GAATCAAGTGAAACTCTTGAAAAAGGATCCAGGAAACGAAGTGAAGCTAAAACTCTACGCGCTATATAAG
CAGGCCACTGAAGGACCTTGTAACATGCCCAAACCAGGTGTATTTGACTTGATCAACAAGGCCAAATGGG
ACGCATGGAATGCCCTTGGCAGCCTGCCCAAGGAAGCTGCCAGGCAGAACTATGTGGATTTGGTGTCCAG
TTTGAGTCCTTCATTGGAATCCTCTAGTCAGGTGGAGCCTGGAACAGACAGGAAATCAACTGGGTTTGAA
ACTCTGGTGGTGACCTCCGAAGATGGCATCACAAAGATCATGTTCAACCGGCCCAAAAAGAAAAATGCCA
TAAACACTGAGATGTATCATGAAATTATGCGTGCACTTAAAGCTGCCAGCAAGGATGACTCAATCATCAC
TGTTTTAACAGGAAATGGTGACTATTACAGTAGTGGGAATGATCTGACTAACTTCACTGATATTCCCCCT
GGTGGAGTAGAGGAGAAAGCTAAAAATAATGCCGTTTTACTGAGGGAATTTGTGGGCTGTTTTATAGATT
TTCCTAAGCCTCTGATTGCAGTGGTCAATGGTCCAGCTGTGGGCATCTCCGTCACCCTCCTTGGGCTATT
CGATGCCGTGTATGCATCTGACAGGGCAACATTTCATACACCATTTAGTCACCTAGGCCAAAGTCCGGAA
GGATGCTCCTCTTACACTTTTCCGAAGATAATGAGCCCAGCCAAGGCAACAGAGATGCTTATTTTTGGAA
AGAAGTTAACAGCGGGAGAGGCATGTGCTCAAGGACTTGTTACTGAAGTTTTCCCTGATAGCACTTTTCA
GAAAGAAGTCTGGACCAGGCTGAAGGCATTTGCAAAGCTTCCCCCAAATGCCTTGAGAATTTCAAAAGAG
GTAATCAGGAAAAGAGAGAGAGAAAAACTACACGCTGTTAATGCTGAAGAATGCAATGTCCTTCAGGGAA
GATGGCTATCAGATGAATGCACAAATGCTGTGGTGAACTTCTTATCCAGAAAATCAAAACTGTGA

Translation (394 aa):
MAMAYLAWRLARRSCPSSLQVTSFPVVQLHMNRTAMRASQKDFENSMNQVKLLKKDPGNEVKLKLYALYK
QATEGPCNMPKPGVFDLINKAKWDAWNALGSLPKEAARQNYVDLVSSLSPSLESSSQVEPGTDRKSTGFE
TLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGNGDYYSSGNDLTNFTDIPP
GGVEEKAKNNAVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPE
GCSSYTFPKIMSPAKATEMLIFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKAFAKLPPNALRISKE
VIRKREREKLHAVNAEECNVLQGRWLSDECTNAVVNFLSRKSKL


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