CHEBI:15603 - L-leucine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name L-leucine
ChEBI ID CHEBI:15603
ChEBI ASCII Name L-leucine
Definition The L-enantiomer of leucine.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:43695, CHEBI:43814, CHEBI:43733, CHEBI:43646, CHEBI:10866, CHEBI:6260, CHEBI:13131, CHEBI:21348
Supplier Information ChemicalBook:CB8742186, ChemicalBook:CB64796923, eMolecules:514488, ZINC000003645145
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C6H13NO2
Net Charge 0
Average Mass 131.17296
Monoisotopic Mass 131.09463
InChI InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChIKey ROHFNLRQFUQHCH-YFKPBYRVSA-N
SMILES CC(C)C[C@H](N)C(O)=O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Chlamydomonas reinhardtii (NCBI:txid3055) See: PubMed
Saccharomyces cerevisiae (NCBI:txid4932) See: PubMed
Saccharomyces cerevisiae (NCBI:txid4932) Source: yeast.sf.net See: PubMed
Escherichia coli (NCBI:txid562) See: PubMed
Escherichia coli (NCBI:txid562) See: PubMed
Homo sapiens (NCBI:txid9606) See: DOI
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
algal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Daphnia magna metabolite
A Daphnia metabolite produced by the species Daphnia magna.
(via leucine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing L-leucine (CHEBI:15603) has role Escherichia coli metabolite (CHEBI:76971)
L-leucine (CHEBI:15603) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
L-leucine (CHEBI:15603) has role algal metabolite (CHEBI:84735)
L-leucine (CHEBI:15603) has role human metabolite (CHEBI:77746)
L-leucine (CHEBI:15603) has role mouse metabolite (CHEBI:75771)
L-leucine (CHEBI:15603) has role plant metabolite (CHEBI:76924)
L-leucine (CHEBI:15603) is a L-α-amino acid (CHEBI:15705)
L-leucine (CHEBI:15603) is a leucine (CHEBI:25017)
L-leucine (CHEBI:15603) is a proteinogenic amino acid (CHEBI:83813)
L-leucine (CHEBI:15603) is a pyruvate family amino acid (CHEBI:26463)
L-leucine (CHEBI:15603) is conjugate acid of L-leucinate (CHEBI:32619)
L-leucine (CHEBI:15603) is conjugate base of L-leucinium (CHEBI:32620)
L-leucine (CHEBI:15603) is enantiomer of D-leucine (CHEBI:28225)
L-leucine (CHEBI:15603) is tautomer of L-leucine zwitterion (CHEBI:57427)
Incoming N-formyl-L-methionyl-L-leucyl-L-phenylalanine (CHEBI:53490) has functional parent L-leucine (CHEBI:15603)
L-Leu-L-Met-NH2 (CHEBI:191171) has functional parent L-leucine (CHEBI:15603)
L-leucine derivative (CHEBI:25018) has functional parent L-leucine (CHEBI:15603)
L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 (CHEBI:191176) has functional parent L-leucine (CHEBI:15603)
L-Phe-Gly-L-Leu-L-Met-NH2 (CHEBI:191175) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Ala (CHEBI:158283) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Ala-Pro (CHEBI:73353) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Asp-Asp (CHEBI:73355) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Asp-Gly (CHEBI:73362) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Leu-Asp (CHEBI:73363) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Leu-His (CHEBI:73365) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Leu-Ser (CHEBI:73366) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Leu-Thr (CHEBI:73368) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Thr-Gln (CHEBI:73372) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Thr-Pro (CHEBI:73292) has functional parent L-leucine (CHEBI:15603)
Ala-Leu-Val-Ser (CHEBI:73375) has functional parent L-leucine (CHEBI:15603)
Asn-Leu (CHEBI:141422) has functional parent L-leucine (CHEBI:15603)
Asn-Leu-Asp-Asp (CHEBI:73408) has functional parent L-leucine (CHEBI:15603)
Asn-Leu-Leu-Ser (CHEBI:73409) has functional parent L-leucine (CHEBI:15603)
Asn-Leu-Phe-Asp (CHEBI:73411) has functional parent L-leucine (CHEBI:15603)
Asp-Leu-Asp-Gln (CHEBI:73428) has functional parent L-leucine (CHEBI:15603)
Asp-Leu-Leu-Gln (CHEBI:73429) has functional parent L-leucine (CHEBI:15603)
Asp-Leu-Leu-Ser (CHEBI:73430) has functional parent L-leucine (CHEBI:15603)
Asp-Leu-Phe-Val (CHEBI:73431) has functional parent L-leucine (CHEBI:15603)
Asp-Leu-Thr-Asp (CHEBI:73433) has functional parent L-leucine (CHEBI:15603)
Asp-Leu-Thr-Ser (CHEBI:73434) has functional parent L-leucine (CHEBI:15603)
DON-10-leucine (CHEBI:149456) has functional parent L-leucine (CHEBI:15603)
Gln-Leu (CHEBI:141429) has functional parent L-leucine (CHEBI:15603)
Gln-Leu-Leu-Pro (CHEBI:73463) has functional parent L-leucine (CHEBI:15603)
Glu-Glu-Leu (CHEBI:156359) has functional parent L-leucine (CHEBI:15603)
Glu-Leu (CHEBI:73506) has functional parent L-leucine (CHEBI:15603)
Glu-Leu-Phe-Ala (CHEBI:73485) has functional parent L-leucine (CHEBI:15603)
Glu-Val-Thr-Leu-Tyr peptide residue (CHEBI:85622) has functional parent L-leucine (CHEBI:15603)
Gly-L-Leu-L-Met-NH2 (CHEBI:191172) has functional parent L-leucine (CHEBI:15603)
Gly-Leu (CHEBI:73514) has functional parent L-leucine (CHEBI:15603)
Ile-Leu-Trp-Trp (CHEBI:73518) has functional parent L-leucine (CHEBI:15603)
Ile-Leu-Val-Tyr (CHEBI:73519) has functional parent L-leucine (CHEBI:15603)
Leu-Ala (CHEBI:73527) has functional parent L-leucine (CHEBI:15603)
Leu-Ala-Asp (CHEBI:73524) has functional parent L-leucine (CHEBI:15603)
Leu-Ala-Gly (CHEBI:73526) has functional parent L-leucine (CHEBI:15603)
Leu-Ala-Ser (CHEBI:73525) has functional parent L-leucine (CHEBI:15603)
Leu-Arg (CHEBI:73528) has functional parent L-leucine (CHEBI:15603)
Leu-Asn (CHEBI:73529) has functional parent L-leucine (CHEBI:15603)
Leu-Asn-His (CHEBI:73530) has functional parent L-leucine (CHEBI:15603)
Leu-Asp-Gln (CHEBI:73561) has functional parent L-leucine (CHEBI:15603)
Leu-Asp-Gly (CHEBI:73562) has functional parent L-leucine (CHEBI:15603)
Leu-Asp-Ser (CHEBI:73563) has functional parent L-leucine (CHEBI:15603)
Leu-Asp-Tyr (CHEBI:73564) has functional parent L-leucine (CHEBI:15603)
Leu-Cys (CHEBI:73582) has functional parent L-leucine (CHEBI:15603)
Leu-enkephalin (CHEBI:89656) has functional parent L-leucine (CHEBI:15603)
Leu-FMDP (CHEBI:74323) has functional parent L-leucine (CHEBI:15603)
Leu-Gly-Pro (CHEBI:6414) has functional parent L-leucine (CHEBI:15603)
Leu-Gly-Ser (CHEBI:138513) has functional parent L-leucine (CHEBI:15603)
Leu-Leu (CHEBI:73531) has functional parent L-leucine (CHEBI:15603)
Leu-Leu-Ala (CHEBI:73565) has functional parent L-leucine (CHEBI:15603)
Leu-Leu-Asn (CHEBI:73566) has functional parent L-leucine (CHEBI:15603)
Leu-Leu-Asp (CHEBI:73567) has functional parent L-leucine (CHEBI:15603)
Leu-Leu-Gly (CHEBI:73568) has functional parent L-leucine (CHEBI:15603)
Leu-Leu-Ser (CHEBI:73569) has functional parent L-leucine (CHEBI:15603)
Leu-Leu-Tyr (CHEBI:6415) has functional parent L-leucine (CHEBI:15603)
Leu-Lys (CHEBI:73583) has functional parent L-leucine (CHEBI:15603)
Leu-Lys-Asp (CHEBI:138514) has functional parent L-leucine (CHEBI:15603)
Leu-Met (CHEBI:73584) has functional parent L-leucine (CHEBI:15603)
Leu-Phe (CHEBI:73585) has functional parent L-leucine (CHEBI:15603)
Leu-Phe-Asn (CHEBI:73570) has functional parent L-leucine (CHEBI:15603)
Leu-Phe-Asp (CHEBI:73571) has functional parent L-leucine (CHEBI:15603)
Leu-Pro (CHEBI:73580) has functional parent L-leucine (CHEBI:15603)
Leu-Pro-Tyr (CHEBI:73581) has functional parent L-leucine (CHEBI:15603)
Leu-Ser (CHEBI:73523) has functional parent L-leucine (CHEBI:15603)
Leu-Ser-Ser-Tyr (CHEBI:73522) has functional parent L-leucine (CHEBI:15603)
Leu-Thr (CHEBI:73589) has functional parent L-leucine (CHEBI:15603)
Leu-Thr-Ala (CHEBI:73572) has functional parent L-leucine (CHEBI:15603)
Leu-Thr-Asp (CHEBI:73573) has functional parent L-leucine (CHEBI:15603)
Leu-Thr-Gln (CHEBI:73574) has functional parent L-leucine (CHEBI:15603)
Leu-Thr-Ser (CHEBI:73575) has functional parent L-leucine (CHEBI:15603)
Leu-Trp (CHEBI:73590) has functional parent L-leucine (CHEBI:15603)
Leu-Tyr (CHEBI:73591) has functional parent L-leucine (CHEBI:15603)
Leu-Val (CHEBI:73579) has functional parent L-leucine (CHEBI:15603)
Leu-Val-Asp (CHEBI:73576) has functional parent L-leucine (CHEBI:15603)
Leu-Val-Gly (CHEBI:73577) has functional parent L-leucine (CHEBI:15603)
Leu-Val-Ser (CHEBI:73578) has functional parent L-leucine (CHEBI:15603)
Lys-Leu-Ser (CHEBI:156358) has functional parent L-leucine (CHEBI:15603)
Lys-Lys-Leu (CHEBI:156355) has functional parent L-leucine (CHEBI:15603)
Ser-Leu-Ser (CHEBI:144475) has functional parent L-leucine (CHEBI:15603)
Tyr-Ile-Leu (CHEBI:165121) has functional parent L-leucine (CHEBI:15603)
L-leucine-d3 (CHEBI:192087) is a L-leucine (CHEBI:15603)
L-leucinium (CHEBI:32620) is conjugate acid of L-leucine (CHEBI:15603)
L-leucinate (CHEBI:32619) is conjugate base of L-leucine (CHEBI:15603)
D-leucine (CHEBI:28225) is enantiomer of L-leucine (CHEBI:15603)
L-leucine residue (CHEBI:30006) is substituent group from L-leucine (CHEBI:15603)
L-leucino group (CHEBI:32622) is substituent group from L-leucine (CHEBI:15603)
L-leucyl group (CHEBI:32621) is substituent group from L-leucine (CHEBI:15603)
L-leucine zwitterion (CHEBI:57427) is tautomer of L-leucine (CHEBI:15603)
IUPAC Name
L-leucine
Synonyms Sources
(2S)-2-amino-4-methylpentanoic acid IUPAC
(2S)-alpha-2-Amino-4-methylvaleric acid KEGG COMPOUND
(2S)-alpha-Leucine KEGG COMPOUND
(S)-(+)-leucine NIST Chemistry WebBook
(S)-leucine NIST Chemistry WebBook
2-Amino-4-methylvaleric acid KEGG COMPOUND
L ChEBI
L-Leucin ChEBI
L-Leucine KEGG COMPOUND
L-Leuzin ChEBI
Leu ChEBI
LEUCINE PDBeChem
Manual Xrefs Databases
1557 DrugCentral
C00001377 KNApSAcK
C00123 KEGG COMPOUND
D00030 KEGG DRUG
DB00149 DrugBank
ECMDB00687 ECMDB
HMDB0000687 HMDB
LEU MetaCyc
LEU_LFOH PDBeChem
Leucine Wikipedia
YMDB00387 YMDB
View more database links
Registry Numbers Types Sources
1721722 Reaxys Registry Number Reaxys
50204 Gmelin Registry Number Gmelin
61-90-5 CAS Registry Number KEGG COMPOUND
61-90-5 CAS Registry Number ChemIDplus
61-90-5 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations
Last Modified
06 February 2023