Uridine (symbol U or Urd) is a glycosylated pyrimidine analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond. The analog is one of the five standard nucleosides which make up nucleic acids, the others being adenosine, thymidine, cytidine and guanosine. The five nucleosides are commonly abbreviated to their symbols, U, A, dT, C, and G, respectively. However, thymidine is more commonly written as 'dT' ('d' represents 'deoxy') as it contains a 2'-deoxyribofuranose moiety rather than the ribofuranose ring found in uridine. This is because thymidine is found in deoxyribonucleic acid (DNA) and usually not in ribonucleic acid (RNA). Conversely, uridine is found in RNA and not DNA. The remaining three nucleosides may be found in both RNA and DNA. In RNA, they would be represented as A, C and G whereas in DNA they would be represented as dA, dC and dG.
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InChI=1S/C9H12N2O6/c12- 3- 4- 6(14) 7(15) 8(17- 4) 11- 2- 1- 5(13) 10- 9(11) 16/h1- 2,4,6- 8,12,14- 15H,3H2,(H,10,13,16) /t4- ,6- ,7- ,8- /m1/s1 |
DRTQHJPVMGBUCF-XVFCMESISA-N |
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |
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Mus musculus
(NCBI:txid10090)
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Source: BioModels - MODEL1507180067
See:
PubMed
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Daphnia magna
(NCBI:txid35525)
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See:
Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyondTine Vandenbrouck, Oliver A.H. Jones, Nathalie Dom, Julian L. Griffin, Wim De CoenEnvironment International 36 (2010) 254-268
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Saccharomyces cerevisiae
(NCBI:txid4932)
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Source: yeast.sf.net
See:
PubMed
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Escherichia coli
(NCBI:txid562)
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See:
PubMed
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Homo sapiens
(NCBI:txid9606)
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See:
DOI
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human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
drug metabolite
fundamental metabolite
Any metabolite produced by all living cells.
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View more via ChEBI Ontology
1-β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione
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ChEBI
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1-β-D-ribofuranosyluracil
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HMDB
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β-Uridine
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HMDB
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u
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ChEBI
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Urd
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CBN
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Uridin
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ChemIDplus
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Uridine
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KEGG COMPOUND
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URIDINE
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PDBeChem
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uridine
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UniProt
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397474
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Gmelin Registry Number
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Gmelin
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58-96-8
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CAS Registry Number
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ChemIDplus
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754904
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Reaxys Registry Number
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Reaxys
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