| Tolbutamide is a first-generation potassium channel blocker, sulfonylurea oral hypoglycemic medication. This drug may be used in the management of type 2 diabetes if diet alone is not effective. Tolbutamide stimulates the secretion of insulin by the pancreas.
It is not routinely used due to a higher incidence of adverse effects compared to newer, second-generation sulfonylureas, such as Glibenclamide. It generally has a short duration of action due to its rapid metabolism, so is safe for use in older people.
It was discovered in 1956. |
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Read full article at Wikipedia
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InChI=1S/C28H48O2/c1- 20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1 |
| QUEDXNHFTDJVIY-DQCZWYHMSA-N |
| CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1 |
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Jatropha curcas
(NCBI:txid180498)
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See:
DOI
|
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Chlamydomonas reinhardtii
(NCBI:txid3055)
|
See:
PubMed
|
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Phaseolus coccineus
(NCBI:txid3886)
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Found in
leaf
(BTO:0000713).
See:
PubMed
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Salmo salar
(NCBI:txid8030)
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See:
PubMed
|
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Homo sapiens
(NCBI:txid9606)
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See:
DOI
|
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Homo sapiens
(NCBI:txid9606)
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Found in
blood
(UBERON:0000178).
See:
PubMed
|
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Homo sapiens
(NCBI:txid9606)
|
Found in
breast milk
(ENVO:02000031).
See:
PubMed
|
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Homo sapiens
(NCBI:txid9606)
|
Found in
faeces
(UBERON:0001988).
See:
PubMed
|
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Homo sapiens
(NCBI:txid9606)
|
From MetaboLights
See:
MetaboLights Study
|
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Homo sapiens
(NCBI:txid9606)
|
From MetaboLights
See:
MetaboLights Study
|
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Homo sapiens
(NCBI:txid9606)
|
From MetaboLights
See:
MetaboLights Study
|
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food antioxidant
An antioxidant that used as a food additives to help guard against food deterioration.
antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
(via vitamin E )
(via tocol )
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plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
algal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
food antioxidant
An antioxidant that used as a food additives to help guard against food deterioration.
fat-soluble vitamin (role)
Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess.
(via vitamin E )
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food antioxidant
An antioxidant that used as a food additives to help guard against food deterioration.
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View more via ChEBI Ontology
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(2R)-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
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(+)-gamma-tocopherol
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HMDB
|
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(+)-γ-tocopherol
|
HMDB
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(2R)-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol
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IUPAC
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(2R)-3,4-dihydro-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
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ChemIDplus
|
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(2R,4'R,8'R)-γ-tocopherol
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HMDB
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(R,R,R)-γ-tocopherol
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HMDB
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7,8-dimethyltocol
|
ChEBI
|
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D-γ-tocopherol
|
ChemIDplus
|
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E308
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ChEBI
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gamma-Tocopherol
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KEGG COMPOUND
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γ-tocopherol
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UniProt
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RRR-γ-tocopherol
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ChEBI
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54-28-4
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CAS Registry Number
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ChemIDplus
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93072
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Reaxys Registry Number
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Reaxys
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