CHEBI:15743 - butanal

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name butanal ChEBI ID CHEBI:15743 Definition A member of the class of butanals that consists of propane bearing a formyl substituent at the 1-position. The parent of the class of butanals. Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:3233, CHEBI:13923, CHEBI:22938 Supplier Information ZINC000004228295 Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Fructose 2,6-bisphosphate, abbreviated Fru-2,6-P2, is a metabolite that allosterically affects the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate glycolysis and gluconeogenesis. Fru-2,6-P2 itself is synthesized and broken down in either direction by the integrated bifunctional enzyme phosphofructokinase 2 (PFK-2/FBPase-2), which also contains a phosphatase domain and is also known as fructose-2,6-bisphosphatase. Whether the kinase and phosphatase domains of PFK-2/FBPase-2 are active or inactive depends on the phosphorylation state of the enzyme. Fructose-6-p-phosphate is phosphorylated by the kinase domain of PFK-2/FBPase-2 to Fru-2,6-P2 when PFK-2/FBPase-2 is active in a dephosphorylated state. This dephosphorylated state is favored by high levels of insulin, which activates the phosphatase domain. The synthesis of Fru-2,6-P2 is performed through a bifunctional enzyme containing both PFK-2 and FBPase-2, which is dephosphorylated, allowing the PFK-2 portion to phosphorylate fructose 6-phosphate using ATP. The breakdown of Fru-2,6-P2 is catalyzed by the phosphorylation of the bifunctional enzyme, which allows FBPase-2 to dephosphorylate fructose 2,6-bisphosphate to produce fructose 6-phosphate and Pi. Read full article at Wikipedia Formula C4H8O Net Charge 0 Average Mass 72.10572 Monoisotopic Mass 72.05751 InChI InChI=1S/C4H8O/c1-2-3-4-5/h4H,2-3H2,1H3 InChIKey ZTQSAGDEMFDKMZ-UHFFFAOYSA-N SMILES [H]C(=O)CCC Metabolite of Species Details Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed Escherichia coli (NCBI:txid562) See: PubMed Roles Classification Biological Role(s): Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). Application(s): biomarker A substance used as an indicator of a biological state. View more via ChEBI Ontology ChEBI Ontology Outgoing butanal (CHEBI:15743) has role Escherichia coli metabolite (CHEBI:76971) butanal (CHEBI:15743) has role biomarker (CHEBI:59163) butanal (CHEBI:15743) has role mouse metabolite (CHEBI:75771) butanal (CHEBI:15743) is a butanals (CHEBI:22939) Incoming 4-acetamidobutanal (CHEBI:7386) has functional parent butanal (CHEBI:15743) 4-methylammoniobutanal (CHEBI:190141) has functional parent butanal (CHEBI:15743) IUPAC Name butanal Synonyms Sources 1-Butanal HMDB 1-Butanal ChemIDplus Aldehyde butyrique ChemIDplus Aldeide butirrica ChemIDplus Butal ChemIDplus Butaldehyde ChemIDplus butan-1-al HMDB Butanal KEGG COMPOUND butanal UniProt Butanaldehyde ChemIDplus Butyl aldehyde NIST Chemistry WebBook Butylaldehyde ChemIDplus Butyral ChemIDplus Butyraldehyd ChemIDplus Butyraldehyde KEGG COMPOUND Butyric aldehyde ChemIDplus Butyrylaldehyde NIST Chemistry WebBook n-Butanal NIST Chemistry WebBook n-Butyl aldehyde NIST Chemistry WebBook n-Butyraldehyde NIST Chemistry WebBook n-C3H7CHO NIST Chemistry WebBook Manual Xrefs Databases Butanal Wikipedia BUTANAL MetaCyc C01412 KEGG COMPOUND HMDB0003543 HMDB View more database links Registry Numbers Types Sources 123-72-8 CAS Registry Number KEGG COMPOUND 123-72-8 CAS Registry Number NIST Chemistry WebBook 123-72-8 CAS Registry Number ChemIDplus 506061 Reaxys Registry Number Reaxys Citations Last Modified 27 January 2016