CHEBI:17552 - GDP

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name GDP
ChEBI ID CHEBI:17552
Definition A purine ribonucleoside 5'-diphosphate resulting from the formal condensation of the hydroxy group at the 5' position of guanosine with pyrophosphoric acid.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42738, CHEBI:5212, CHEBI:13327, CHEBI:14379, CHEBI:24448
Supplier Information ChemicalBook:CB0456205, eMolecules:29542138, ZINC000003869280
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Phosphoserine (abbreviated as SEP or J) is an ester of serine and phosphoric acid. Phosphoserine is a component of many proteins as the result of posttranslational modifications. The phosphorylation of the alcohol functional group in serine to produce phosphoserine is catalyzed by various types of kinases. Through the use of technologies that utilize an expanded genetic code, phosphoserine can also be incorporated into proteins during translation. It is a normal metabolite found in human biofluids. Phosphoserine has three potential coordination sites (carboxyl, amine and phosphate group) Determination of the mode of coordination between phosphorylated ligands and metal ions occurring in an organism is a first step to explain the function of the phosphoserine in bioinorganic processes.
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Formula C10H15N5O11P2
Net Charge 0
Average Mass 443.20072
Monoisotopic Mass 443.02433
InChI InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKey QGWNDRXFNXRZMB-UUOKFMHZSA-N
SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Escherichia coli (NCBI:txid562) See: PubMed
Roles Classification
Biological Role(s): Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
uncoupling protein inhibitor
Any inhibitor that acts on uncoupling protein.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
(via nucleoside 5'-diphosphate )
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ChEBI Ontology
Outgoing GDP (CHEBI:17552) has role Escherichia coli metabolite (CHEBI:76971)
GDP (CHEBI:17552) has role mouse metabolite (CHEBI:75771)
GDP (CHEBI:17552) has role uncoupling protein inhibitor (CHEBI:145437)
GDP (CHEBI:17552) is a guanosine 5'-phosphate (CHEBI:37121)
GDP (CHEBI:17552) is a purine ribonucleoside 5'-diphosphate (CHEBI:37038)
GDP (CHEBI:17552) is conjugate acid of GDP(2−) (CHEBI:65180)
Incoming 2'-MANT-GDP (CHEBI:85432) has functional parent GDP (CHEBI:17552)
3'-MANT-GDP (CHEBI:85434) has functional parent GDP (CHEBI:17552)
7-methylguanosine 5'-diphosphate (CHEBI:63729) has functional parent GDP (CHEBI:17552)
7-methylguanosine 5'-diphosphate(1+) (CHEBI:63730) has functional parent GDP (CHEBI:17552)
8-oxo-GDP (CHEBI:65134) has functional parent GDP (CHEBI:17552)
GDP-β-S (CHEBI:38309) has functional parent GDP (CHEBI:17552)
GDP-sugar (CHEBI:21169) has functional parent GDP (CHEBI:17552)
GDP-valienol (CHEBI:128754) has functional parent GDP (CHEBI:17552)
MANT-GDP (CHEBI:84677) has functional parent GDP (CHEBI:17552)
GDP(2−) (CHEBI:65180) is conjugate base of GDP (CHEBI:17552)
IUPAC Name
guanosine 5'-(trihydrogen diphosphate)
Synonyms Sources
GDP KEGG COMPOUND
Guanosine 5'-diphosphate KEGG COMPOUND
Guanosine diphosphate KEGG COMPOUND
Manual Xrefs Databases
C00035 KEGG COMPOUND
DB04315 DrugBank
G10620 KEGG GLYCAN
GDP PDBeChem
Guanosine_diphosphate Wikipedia
HMDB0001201 HMDB
View more database links
Registry Number Type Source
146-91-8 CAS Registry Number KEGG COMPOUND
Citations Types Sources
18439413 PubMed citation Europe PMC
9271366 PubMed citation Europe PMC
Last Modified
20 November 2019