| Nifedipine, sold under the brand name Procardia among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. It is one of the treatments of choice for Prinzmetal angina. It may be used to treat severe high blood pressure in pregnancy. Its use in preterm labor may allow more time for steroids to improve the baby's lung function and provide time for transfer of the mother to a well qualified medical facility before delivery. It is a calcium channel blocker of the dihydropyridine type. Nifedipine is taken by mouth and comes in fast- and slow-release formulations.
Common side effects include lightheadedness, headache, feeling tired, leg swelling, cough, and shortness of breath. Serious side effects may include low blood pressure and heart failure. Nifedipine is considered safe in pregnancy and breastfeeding.
Nifedipine was patented in 1967, and approved for use in the United States in 1981. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2022, it was the 151st most commonly prescribed medication in the United States, with more than 3 million prescriptions. |
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Read full article at Wikipedia
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| InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15) |
| QIVBCDIJIAJPQS-UHFFFAOYSA-N |
| NC(Cc1c[nH]c2ccccc12)C(O)=O |
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Daphnia magna
(NCBI:txid35525)
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See:
Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyondTine Vandenbrouck, Oliver A.H. Jones, Nathalie Dom, Julian L. Griffin, Wim De CoenEnvironment International 36 (2010) 254-268
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Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
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Daphnia magna metabolite
A Daphnia metabolite produced by the species Daphnia magna.
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View more via ChEBI Ontology
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2-amino-3-(1H-indol-3-yl)propanoic acid
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IUPAC
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alpha-Amino-beta-(3-indolyl)-propionic acid
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KEGG COMPOUND
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α-amino-β-3-indolepropionic acid
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ChEBI
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β-3-indolylalanine
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ChEBI
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Htrp
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IUPAC
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triptófano
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ChEBI
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Trp
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ChEBI
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Tryptophan
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KEGG COMPOUND
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tryptophane
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ChEBI
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W
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ChEBI
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4532
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Gmelin Registry Number
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Gmelin
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54-12-6
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CAS Registry Number
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NIST Chemistry WebBook
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54-12-6
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CAS Registry Number
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ChemIDplus
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86196
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Reaxys Registry Number
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Reaxys
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