CHEBI:60473 - 5,10-methylenetetrahydrofolate polyglutamate macromolecule

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ChEBI Name 5,10-methylenetetrahydrofolate polyglutamate macromolecule
ChEBI ID CHEBI:60473
Definition An ionic macromolecule consisting of (6R)-5,10-methylenetetrahydrofolate(2−) with an arbitrary number of glutamate residues attached as a polypeptide to the single existent one.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Peter D'Eustachio
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Formula (C5H6NO3)n.C15H15N6O3
Net Charge -2
ChEBI Ontology
Outgoing 5,10-methylenetetrahydrofolate polyglutamate macromolecule (CHEBI:60473) has functional parent (6R)-5,10-methylenetetrahydrofolate(2−) (CHEBI:15636)
5,10-methylenetetrahydrofolate polyglutamate macromolecule (CHEBI:60473) is a ionic macromolecule (CHEBI:53368)
Incoming 5,10-methylenetetrahydrofolate polyglutamate polymer (CHEBI:61443) has part 5,10-methylenetetrahydrofolate polyglutamate macromolecule (CHEBI:60473)
(6R)-5,10-methylenetetrahydrofolate poly(γ-L-glutamate) macromolecule (CHEBI:136572) is a 5,10-methylenetetrahydrofolate polyglutamate macromolecule (CHEBI:60473)
Synonym Source
5,10-methylenetetrahydrofolate polyglutamate ChEBI
Last Modified
17 March 2017
General Comment
2011-01-13 The added residues are thought to help trap the molecule inside cells, but not to affect its reactivity otherwise.