CHEBI:62830 - dTDP-4-dehydro-β-L-rhamnose(2−)

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ChEBI Name dTDP-4-dehydro-β-L-rhamnose(2−) ChEBI ID CHEBI:62830 ChEBI ASCII Name dTDP-4-dehydro-beta-L-rhamnose(2-) Definition The nucleotide-sugar oxoanion that is the dianion formed from dTDP-4-dehydro-β-L-rhamnose by loss of two protons from its diphospho group. Intermediate in dTDP-rhamnose biosynthesis. Stars This entity has been manually annotated by the ChEBI Team. Submitter R. Stephan Supplier Information No supplier information found for this compound. Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C16H22N2O15P2 Net Charge -2 Average Mass 544.29780 Monoisotopic Mass 544.05064 InChI InChI=1S/C16H24N2O15P2/c1-6-4-18(16(24)17-14(6)23)10-3-8(19)9(31-10)5-29-34(25,26)33-35(27,28)32-15-13(22)12(21)11(20)7(2)30-15/h4,7-10,12-13,15,19,21-22H,3,5H2,1-2H3,(H,25,26)(H,27,28)(H,17,23,24)/p-2/t7-,8-,9+,10+,12+,13+,15+/m0/s1 InChIKey PSXWNITXWWECNY-LPVGZGSHSA-L SMILES C[C@@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H](C[C@@H]2O)n2cc(C)c(=O)[nH]c2=O)[C@H](O)[C@H](O)C1=O ChEBI Ontology Outgoing dTDP-4-dehydro-β-L-rhamnose(2−) (CHEBI:62830) is a nucleotide-sugar oxoanion (CHEBI:59737) dTDP-4-dehydro-β-L-rhamnose(2−) (CHEBI:62830) is conjugate base of dTDP-4-dehydro-β-L-rhamnose (CHEBI:45868) Incoming dTDP-4-dehydro-β-L-rhamnose (CHEBI:45868) is conjugate acid of dTDP-4-dehydro-β-L-rhamnose(2−) (CHEBI:62830) IUPAC Name thymidine 5'-[3-(6-deoxy-β-L-lyxo-hexopyranosyl-4-ulose) diphosphate] Synonyms Sources dTDP-4-dehydro-β-L-rhamnose UniProt dTDP-6-deoxy-β-L-lyxo-hex-4-ulose(2−) ChEBI dTDP-L-lyxo-hexulose SUBMITTER Citation Hirao Y, Mihara Y, Kira I, Abe I, Yokozeki K (2013) Enzymatic production of L-alanyl-L-glutamine by recombinant E. coli expressing α-amino acid ester acyltransferase from Sphingobacterium siyangensis. Bioscience, biotechnology, and biochemistry 77, 618-623 (Source: SUBMITTER) [PubMed:23470770] [show Abstract] An enzymatic production method for synthesizing L-alanyl-L-glutamine (Ala-Gln) from L-alanine methyl ester hydrochloride (AlaOMe) and L-glutamine (Gln) was developed in this study. The cultivation conditions for an Escherichia coli strain overexpressing α-amino acid ester acyltransferase from Sphingobacterium siyangensis AJ 2458 (SAET) and reaction conditions for Ala-Gln production were optimized. A high cell density culture broth prepared by fed-batch cultivation showed 440 units/mL of Ala-Gln-producing activity. In addition, an Ala-Gln-producing reaction using intact E. coli cells overexpressing SAET under optimum conditions was conducted. A total Ala-Gln yield of 69.7 g/L was produced in 40 min. The molar yield was 67% against both AlaOMe and Gln. Last Modified 21 October 2013