Fluorine F-18
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Fluorine F-18
- DrugBank Accession Number
- DB13134
- Background
Fluorine-18 is under investigation in clinical trial NCT00870974 (A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 18.0009
Monoisotopic: 18.000937667 - Chemical Formula
- F
- Synonyms
- Fluorine-18
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as homogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas.
- Kingdom
- Inorganic compounds
- Super Class
- Homogeneous non-metal compounds
- Class
- Homogeneous halogens
- Sub Class
- Not Available
- Direct Parent
- Homogeneous halogens
- Alternative Parents
- Not Available
- Substituents
- Homogeneous halogen
- Molecular Framework
- Not Available
- External Descriptors
- fluorine atom (CHEBI:36939)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- GZ5I74KB8G
- CAS number
- 13981-56-1
- InChI Key
- YCKRFDGAMUMZLT-BJUDXGSMSA-N
- InChI
- InChI=1S/F/i1-1
- IUPAC Name
- (18F)fluoranyl
- SMILES
- [18F]
References
- General References
- Not Available
- External Links
- PubChem Compound
- 131704324
- PubChem Substance
- 347829252
- ChemSpider
- 21865283
- ChEBI
- 36939
- Wikipedia
- Fluorine-18
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Active Not Recruiting Diagnostic Brain Neoplasm / Low-Grade Glioma / Recurrent Glioblastoma / Recurrent WHO Grade III Glioma / Recurrent World Health Organization (WHO) Grade II Glioma 1 2 Active Not Recruiting Diagnostic Estrogen Receptor Positive / Primary or Recurrent Breast Carcinoma / Stage IV Breast Cancer AJCC v6 and v7 1 2 Active Not Recruiting Diagnostic HER2 negative / Progesterone Receptor Negative / Progesterone Receptor Positive / Stage IV Breast Cancer AJCC v6 and v7 1 2 Active Not Recruiting Treatment Stage III Non-Small Cell Lung Cancer AJCC v7 / Stage IIIA Non-Small Cell Lung Cancer AJCC v7 / Stage IIIB Non-Small Cell Lung Cancer AJCC v7 1 2 Completed Diagnostic Adult Hepatocellular Carcinoma / Localized Resectable Adult Liver Carcinoma 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 0.37 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 0.87 m3·mol-1 Chemaxon Polarizability 0.44 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at October 21, 2016 03:34 / Updated at June 12, 2020 16:53