KEGG ENZYME: 1.5.1.19

ENZYME: 1.5.1.19

Entry

EC 1.5.1.19                 Enzyme

Name

D-nopaline dehydrogenase;
D-nopaline synthase;
nopaline dehydrogenase;
nopaline synthase;
NOS;
2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)

Class

Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)

Reaction(IUBMB)

N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH + H+ [RN:R00563]

Reaction(KEGG)

R00563

Substrate

N2-(D-1,3-dicarboxypropyl)-L-arginine [CPD:C01682];
NADP+ [CPD:C00006];
H2O [CPD:C00001]

Product

L-arginine [CPD:C00062];
2-oxoglutarate [CPD:C00026];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

In the reverse direction, forms D-nopaline from L-arginine and D-ornaline from L-ornithine.

History

EC 1.5.1.19 created 1984

Pathway

ec00330

Arginine and proline metabolism

ec01100

Metabolic pathways

Orthology

K00296

D-nopaline dehydrogenase

Genes

ATU:	Atu6015(nos)

ALF:	CFBP5473_23905

AVV:	RvVAT039_pl10620

ASAL:

CFBP5507_27335

AVI:	Avi_8195(nos)

RTU:	PR017_22240 PR017_22745

NEN:	NCHU2750_55510(nos)

Reference

1 [PMID:476084]

Authors

Kemp JD, Sutton DW, Hack E.

Title

Purification and characterization of the crown gall specific enzyme nopaline synthase.

Journal

Biochemistry 18:3755-60 (1979)
DOI:10.1021/bi00584a017

Other DBs

ExplorEnz - The Enzyme Database:

1.5.1.19

IUBMB Enzyme Nomenclature:

1.5.1.19

ExPASy - ENZYME nomenclature database:

1.5.1.19

BRENDA, the Enzyme Database:

1.5.1.19

CAS:	64763-57-1

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