KEGG ENZYME: 2.3.1.13

ENZYME: 2.3.1.13

Entry

EC 2.3.1.13                 Enzyme

Name

glycine N-acyltransferase;
glycine acyltransferase;
glycine-N-acylase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acyl-CoA:glycine N-acyltransferase

Reaction(IUBMB)

acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395]

Reaction(KEGG)

R00395

Substrate

acyl-CoA [CPD:C00040];
glycine [CPD:C00037]

Product

CoA [CPD:C00010];
N-acylglycine [CPD:C02055]

Comment

The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC 2.3.1.68 glutamine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.

History

EC 2.3.1.13 created 1961

Orthology

K00628

glycine N-acyltransferase / glycine N-benzoyltransferase

K22749

glycine N-acyltransferase

Genes

HSA:	10249(GLYAT) 219970(GLYATL2)

PTR:	451206(GLYATL2) 748398(GLYAT)

PPS:	100979655(GLYATL2) 100980359(GLYAT)

GGO:	101124654(GLYAT) 101125629(GLYATL2)

PON:	100173810(GLYAT) 100443306

NLE:	100588653 100593268(GLYATL2) 100593830

HMH:	116468207(GLYATL2) 116468815(GLYAT)

MCC:	114672254 701659(GLYAT)

MCF:	102146442(GLYAT)

MTHB:

126936171

MNI:	105496094(GLYAT)

CSAB:

103235080(GLYAT)

CATY:

105600759(GLYAT)

PANU:

101001949(GLYAT)

TGE:	112606476(GLYAT)

MLEU:

105530757(GLYAT)

RRO:	104680418(GLYAT)

RBB:	108541348(GLYAT)

TFN:	117080716(GLYAT)

PTEH:

111544978(GLYAT)

CANG:

105527196(GLYAT)

CJC:	100395000(GLYAT) 100395366(GLYATL2)

SBQ:	101033622(GLYAT) 101033935(GLYATL2)

CIMI:

108282878(GLYATL2) 108282879(GLYAT)

CSYR:

103253803(GLYATL2) 103269914 103269915

MMUR:

105863123(GLYATL2) 105863143

LCAT:

123642731 123642734(GLYATL2)

PCOQ:

105810009(GLYATL2) 105810068

OGA:	100944583(GLYAT) 100958233 100958553 100959183(GLYATL2)

MMU:	107146(Glyat) 64697(Keg1)

MCAL:

110285861(Glyat) 110285927

MPAH:

110333589 110334444

RNO:	171179(Glyatl2) 293779(Glyat)

MCOC:

116101066 116101070

ANU:	117721946 117723317

MUN:	110565447 110565760

CGE:	100774147 100774433 100774725

MAUA:

101831003 101841125

PROB:

127228904 127228906

PLEU:

114703386 114703387

MORG:

121454269(Glyat) 121454334 121454336 121454473 121454631

MFOT:

126498309 126498312 126498313 126498314 126498315

AAMP:

119811672 119812880 119812899 119812916

NGI:	103733343 103733398

HGL:	101711412 101712854 101713466(Glyat)

CPOC:

100730253 100733575

CCAN:

109678086

DORD:

105995257 105995531

DSP:	122104903 122104904

PLOP:

125362689 125362690

NCAR:

124958958 124960038

MMMA:

107135854 107135857(Glyat)

OCU:

100345309

OPI:

101532529

TUP:	102485105 102488756(GLYAT) 102500544(GLYATL2)

GVR:	103597522(GLYATL2) 103597524 103608043

CFA:	483463(GLYAT)

CLUD:

112663397(GLYAT)

VVP:	112930488(GLYAT)

VLG:	121471923(GLYAT)

NPO:	129494049(GLYAT)

AML:

100476924

UMR:

103666140

UAH:	113246537(GLYAT)

UAR:	123785071(GLYAT)

ELK:	111149525 111150163

LLV:

125078915

MPUF:

101672896(GLYAT) 101689032(GLYATL2)

MNP:	132015697(GLYATL2) 132020826

MLK:	131811648(GLYATL2) 131812987(GLYAT)

NVS:	122912951 122912953(GLYATL2)

ORO:	101370241(GLYAT) 101370831

EJU:	114215251(GLYATL2) 114215371

ZCA:	113915065 113915068(GLYATL2)

MLX:	118015877(GLYAT) 118016303

NSU:

110575841

LWW:

102749519

FCA:	101094699(GLYATL2) 101097840(GLYAT)

PYU:	121043386(GLYAT) 121043768(GLYATL2)

PCOO:

112865400(GLYAT) 112866035(GLYATL2)

PBG:	122482826(GLYATL2) 122483802

PVIV:

125176690 125176691(GLYATL2)

LRUF:

124504661 124506454

PTG:	102966010(GLYAT) 102966774(GLYATL2)

PPAD:

109246472(GLYAT) 109247014(GLYATL2)

PUC:	125933287 125933299

AJU:

106986792

HHV:	120240296(GLYATL2) 120240385

BTA:	104974345 281787(GLYAT) 515352(GLYATL2) 518623

BOM:	102270060 102270337 102274551(GLYATL2) 102284395

BIU:	109569442(GLYATL2) 109569864 109569929 109569937

BBUB:

102393759 102402141 102407775

BBIS:

104983647(GLYAT) 104987662 104989684 105001532 105001538

CHX:	102175500 102176061 102176349(GLYATL2)

OAS:	101108419 101108685(GLYAT) 101109387(GLYATL2)

BTAX:

128060630 128060651 128060998(GLYATL2)

ODA:	120877109 120877110 120877113(GLYATL2)

CCAD:

122449919(GLYATL2) 122449920 122449923

MBEZ:

129537452 129537453 129554872 129554876 129554878(GLYATL2)

SSC:	100518109 100518644 100525206(GLYATL2)

CFR:	102511836(GLYATL2) 102512308 102523093

CBAI:

105070055 105070057 105070059(GLYATL2)

CDK:	105094918(GLYATL2) 105094920 105094922

VPC:	102531980(GLYATL2) 102532226 102532484

BACU:

103012684(GLYAT) 103013536

BMUS:

118898704 118900085

LVE:	103084960 103085242

OOR:	101286759 101287020

DLE:	111183924 111183925

PCAD:

102988596 102988877

PSIU:

116758227 116758717

NASI:

112402161 112402409

ECB:	100066603 100068374

EPZ:	103556884 103556886

EAI:	106825141(GLYAT) 106825142

MYB:	102246796 102250190 102250899(GLYATL2)

MYD:	102767900(GLYAT) 102768179 102769546 102770418(GLYATL2)

MMYO:

118663701 118664988(GLYATL2) 118664990 118664992

MLF:	102438632(GLYATL2) 102441742 102442368 102442997 111822960

PKL:	118712810(GLYATL2) 118712812 118712813 118712815

EFUS:

103292664 103292666 103292667 103292671(GLYATL2) 103292757

MNA:	107527657(GLYATL2) 107527658(GLYAT)

DRO:	112303553(GLYATL2) 112303558

SHON:

118996870(GLYATL2)

AJM:	119058869(GLYATL2)

PDIC:

114500943(GLYATL2) 114500944(GLYAT)

PHAS:

123829264 123829308 123829310(GLYATL2)

MMF:	118628366 118628713 118628714(GLYATL2)

PPAM:

129062624(GLYATL2) 129062729

HAI:	109389993(GLYAT) 109390041(GLYATL2)

RFQ:	117029890(GLYATL2) 117030569

PALE:

102891747 102895685

PGIG:

120600763

PVP:

105309550

RAY:	107497335 107497336(GLYAT)

TOD:	119254329(GLYATL2) 119254330 119254331 119255256

SARA:

101552140

LAV:	100662425 100662985 100663214 100668301(GLYAT) 100668589 104847055

TMU:	101350172 101357009

ETF:	101657783 101658105

DNM:

101423027

MDO:	100027269(GLYATL2) 100027301 100027341

GAS:	123251946 123251997 123252718 123256209

SHR:	100916236 100916412 100916499 100916674 100918927

AFZ:	127539822 127540452 127540488 127541632 127541634

PCW:	110200706 110200708

OAA:	100081664 114810122

NPR:

108798821

RTEM:

120909259 120909260

BBUF:

121003462 121003478

BGAR:

122940898 122941436 122942117

MUO:	115460522 115482194 115482199 115482242

GSH:	117348575 117348576

BBEL:

109482204

MQU:

129001864

HAME:

121854082 121862398 121864063

HRJ:

124261194

OSN:

115223248

» show all

Reference

1 [PMID:457678]

Authors

Nandi DL, Lucas SV, Webster LT Jr

Title

Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.

Journal

J Biol Chem 254:7230-7 (1979)

Sequence

[bta:281787]

Reference

2 [PMID:13174534]

Authors

SCHACHTER D, TAGGART JV.

Title

Glycine N-acylase: purification and properties.

Journal

J Biol Chem 208:263-75 (1954)

Reference

3 [PMID:931988]

Authors

Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ.

Title

Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man.

Journal

J Biol Chem 251:3352-8 (1976)

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.13

IUBMB Enzyme Nomenclature:

2.3.1.13

ExPASy - ENZYME nomenclature database:

2.3.1.13

BRENDA, the Enzyme Database:

2.3.1.13

CAS:

9029-95-2

DBGET integrated database retrieval system