| Entry |
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| Name |
oxalate decarboxylase;
oxalate carboxy-lyase
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| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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| Sysname |
oxalate carboxy-lyase (formate-forming)
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| Reaction(IUBMB) |
oxalate + H+ = formate + CO2 [RN: R00522]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme from Bacillus subtilis contains manganese and requires O2 for activity, even though there is no net redox change.
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| History |
EC 4.1.1.2 created 1961
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| Pathway |
| ec00630 | Glyoxylate and dicarboxylate metabolism |
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| Orthology |
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| Genes |
| PSCO: | LY89DRAFT_693988 LY89DRAFT_770501 |
| ZTR: | MYCGRDRAFT_41798 MYCGRDRAFT_71618 |
| CBET: | CB0940_06136 CB0940_10045 |
| PCO: | PHACADRAFT_260851 PHACADRAFT_30972 |
| ADL: | AURDEDRAFT_64340 AURDEDRAFT_64423 |
| CLAP: | NCTC11466_01172(oxdD) |
| SFJ: | SAMEA4384070_2395(oxdD) |
| PVA: | Pvag_pPag30056(oxdC) |
| BMN: | BMA10247_A1067(oxdD) |
| BPL: | BURPS1106A_A1331(oxdD) |
| BPD: | BURPS668_A1413(oxdD) |
| BGD: | bgla_1g08510 bgla_2g07050 |
| BGO: | BM43_2239(oxdD) BM43_4352(oxdD) |
| PMEG: | FNZ07_05005 FNZ07_17790 |
| PEW: | KZJ38_11220 KZJ38_17680 |
| PKF: | RW095_04430 RW095_05835 RW095_07470 |
| PHYL: | HB779_21965 HB779_23190 |
| RGR: | FZ934_19410 FZ934_25695 |
| BJU: | BJ6T_14650 BJ6T_62210 BJ6T_62890 |
| BJP: | RN69_07235 RN69_30140 RN69_30480 |
| BRK: | CWS35_28055 CWS35_36435 |
| BBAN: | J4G43_019685 J4G43_020090 J4G43_040595 |
| MAQU: | Maq22A_c21415 Maq22A_c26540 |
| MPHY: | MCBMB27_01168 MCBMB27_05088 |
| MEE: | DA075_00570 DA075_02720 DA075_29550 |
| METX: | A3862_01730 A3862_23230 |
| METS: | DK389_03150 DK389_19650 |
| MIND: | mvi_52930(oxdD) mvi_59890(oxdC) |
| MTAD: | M6G65_00555 M6G65_08485 |
| MSL: | Msil_0110 Msil_0722 Msil_2183 Msil_2678 |
| MTUN: | MTUNDRAET4_0161(oxdD) MTUNDRAET4_2865(oxdD) |
| MEDK: | QEV83_07890 QEV83_08250 QEV83_17345 |
| BBAR: | RHAL1_03023 RHAL1_03513(oxdC) |
| MBRY: | B1812_07745 B1812_21095 B1812_21100 |
| PSIN: | CAK95_15440 CAK95_20915 |
| LCK: | HN018_04995 HN018_23020 |
| NAO: | Y958_08235 Y958_17840 |
| BSU: | BSU18670(yoaN) BSU33240(oxdC) |
| BSR: | I33_2097(oxdD) I33_3439 |
| BSH: | BSU6051_18670(yoaN) BSU6051_33240(oxdC) |
| BSY: | I653_09720 I653_16090 |
| BSUT: | BSUB_02008(oxdD) BSUB_03551(oxdC) |
| BSUL: | BSUA_02008(oxdD) BSUA_03551(oxdC) |
| BSUS: | Q433_11045 Q433_18230 |
| BSN: | BSn5_00710 BSn5_07540 |
| BSQ: | B657_18670(yoaN) B657_33240(oxdC) |
| BSX: | C663_1932 C663_3192(oxdC) |
| BSP: | U712_09835 U712_16635 |
| BST: | GYO_2251(oxdD) GYO_3633 |
| BLH: | BaLi_c33460(yoaN) BaLi_c36390(oxdC) |
| BAY: | RBAM_020670 RBAM_030390 |
| BAQ: | BACAU_2075(oxdC1) BACAU_3063(oxdC3) |
| BYA: | BANAU_2218(oxdC1) BANAU_3228(oxdC3) |
| BAMP: | B938_10680 B938_15555 |
| BQY: | MUS_2496(oxdC1) MUS_3634(oxdC) |
| BAML: | BAM5036_1994(oxdC) BAM5036_2951(oxdC) |
| BAMA: | RBAU_2206(oxdC) RBAU_3170(oxdC) |
| BAMN: | BASU_1995(oxdC1) BASU_2957(oxdC) |
| BAMB: | BAPNAU_1520(oxdC1) BAPNAU_3219(oxdC3) |
| BAMT: | AJ82_11735 AJ82_17185 |
| BAMY: | V529_23340(oxdC1) V529_33010(oxdC) |
| BMP: | NG74_02166(oxdC_1) NG74_03188(oxdC_2) |
| BAO: | BAMF_2152(oxdC1) BAMF_3167(oxdC) |
| BAZ: | BAMTA208_05710(oxdC1) BAMTA208_16835(oxdC) |
| BQL: | LL3_02435(oxdC) LL3_03450(oxdC) |
| BXH: | BAXH7_01194(oxdC1) BAXH7_03438(oxdC) |
| BAMI: | KSO_003965 KSO_009085 |
| BAMC: | U471_21320 U471_31530 |
| BAMF: | U722_11290 U722_16325 |
| BSIA: | CWD84_03915 CWD84_10625 |
| BAE: | BATR1942_09125 BATR1942_14555 |
| BSON: | S101395_02363(oxdD) S101395_04304 |
| BTEQ: | G4P54_10720(oxdD) G4P54_17050(oxdC) |
| BIQ: | AN935_09765 AN935_16720 |
| BSTR: | QI003_10115(oxdD) QI003_13545(oxdD) QI003_20105(oxdC) |
| BPUM: | BW16_04325 BW16_15695 |
| BPUS: | UP12_04340 UP12_15270 |
| BGY: | BGLY_2489 BGLY_3965(oxdC) |
| BXI: | BK049_03975 BK049_12455 |
| BALT: | CFN77_04215 CFN77_15605 |
| BAER: | BAE_03125 BAE_11780 |
| BSAF: | BSL056_04180 BSL056_16325 |
| BCAB: | EFK13_10350(oxdD) EFK13_17060(oxdC) |
| BACW: | QR42_04130 QR42_14700 |
| BACP: | SB24_13550 SB24_18380 |
| BACB: | OY17_13610 OY17_18510 |
| BACY: | QF06_08465 QF06_14955 |
| BACL: | BS34A_20690(yoaN) BS34A_36280(oxdC) |
| BALM: | BsLM_1991 BsLM_3331 |
| BACS: | AUL54_14420 AUL54_19485 |
| PPQ: | PPSQR21_022900 PPSQR21_023030 |
| PKB: | B4V02_13510 B4V02_13635 |
| PBAC: | HUB98_21780 HUB98_26830 |
| PMAH: | PTQ21_09885 PTQ21_15115 |
| PPAB: | KET34_05025 KET34_11190 |
| MSAK: | MSAS_13530 MSAS_54250 |
| MCOO: | MCOO_17570 MCOO_17580 |
| MPAA: | MKK62_15580 MKK62_15585 |
| MWU: | PT015_02330 PT015_02335 |
| MPHL: | MPHLCCUG_01971(oxdC) |
| MAUU: | NCTC10437_01750(oxdC) |
| MMOR: | MMOR_07120 MMOR_13060 |
| MGAD: | MGAD_36360 MGAD_41230 |
| MAUB: | MAUB_05370 MAUB_05380 MAUB_05400 MAUB_53500 |
| MPHU: | MPHO_07120 MPHO_15960 |
| MMUC: | C1S78_010410 C1S78_014755 |
| MSEI: | MSEDJ_11670 MSEDJ_58720 |
| MSAL: | DSM43276_04589(oxdC) |
| NTP: | CRH09_17555 CRH09_25370 |
| AGF: | ET445_06580 ET445_09105 |
| SUBA: | LQ955_06600 LQ955_17815 |
| SYY: | SYNGTS_0976(sll1358) |
| SYT: | SYNGTI_0976(sll1358) |
| SYS: | SYNPCCN_0975(sll1358) |
| SYQ: | SYNPCCP_0975(sll1358) |
| KBB: | ccbrp13_25290(oxdD) ccbrp13_29600 |
| AAGG: | ETAA8_12440(oxdD_1) |
| LPAV: | PLANPX_0385 PLANPX_2537 |
| ACM: | AciX9_3926 AciX9_3934 AciX9_4412 |
| GMA: | AciX8_0011 AciX8_2470 AciX8_2544 |
| GRW: | FTO74_09860 FTO74_14530 |
| GRB: | GOB94_06455 GOB94_10210 |
| ABAS: | ACPOL_3052 ACPOL_4101 |
| ADIN: | H7849_05425 H7849_13325 |
| CHRY: | CEY12_07155 CEY12_21325 |
| CGLE: | NCTC11432_01155(oxdD) |
| TAA: | NMY3_00117(oxdD) NMY3_01808(oxdC) |
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| Reference |
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| Authors |
HAYAISHI O, JAKOBY WB, OHMURA E. |
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| Title |
Enzymatic decarboxylation of oxalic acid. |
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| Journal |
J Biol Chem 222:435-46 (1956) |
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| Reference |
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| Authors |
Tanner A, Bornemann S |
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| Title |
Bacillus subtilis YvrK is an acid-induced oxalate decarboxylase. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Tanner A, Bowater L, Fairhurst SA, Bornemann S. |
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| Title |
Oxalate decarboxylase requires manganese and dioxygen for activity. Overexpression and characterization of Bacillus subtilis YvrK and YoaN. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.1.1.2 |
| ExPASy - ENZYME nomenclature database: | 4.1.1.2 |
| BRENDA, the Enzyme Database: | 4.1.1.2 |
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