Human (GRCh38.p14)
Description

DNA topoisomerase III alpha [Source:HGNC Symbol;Acc:HGNC:11992]

Gene Synonyms

TOP3, ZGRF7

Location

Chromosome 17: 18,271,428-18,315,007 reverse strand.

GRCh38:CM000679.2

View alleles of this gene on alternative sequences

About this gene

This gene has 19 transcripts (splice variants), 1 gene allele, 204 orthologues, 1 paralogue and is associated with 4 phenotypes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000321105.10TOP3A-20165961001aaENSP00000321636.5
 
Protein coding
CCDS11194Q13472-1 NM_004618.5MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000580095.5TOP3A-2082929976aaENSP00000462790.1
 
Protein coding
Q13472-2 -TSL:1CDS 3' incomplete
ENST00000489131.1TOP3A-20658225aaENSP00000465864.1
 
Protein coding
K7EL07 -TSL:3CDS 5' incomplete
ENST00000584582.5TOP3A-216366169aaENSP00000462136.1
 
Nonsense mediated decay
J3KRR9 -TSL:5
ENST00000582981.5TOP3A-213323989aaENSP00000462378.1
 
Nonsense mediated decay
J3KS96 -TSL:2
ENST00000461127.5TOP3A-202823139aaENSP00000464338.1
 
Nonsense mediated decay
J3QR18 -TSL:3
ENST00000581536.5TOP3A-210766163aaENSP00000466641.1
 
Nonsense mediated decay
K7EMT6 -TSL:5CDS 5' incomplete
ENST00000585031.2TOP3A-21957595aaENSP00000464493.1
 
Nonsense mediated decay
J3QS25 -TSL:4
ENST00000582122.1TOP3A-211553133aaENSP00000466099.1
 
Nonsense mediated decay
K7ELI7 -TSL:4CDS 5' incomplete
ENST00000493648.1TOP3A-20750352aaENSP00000465014.1
 
Nonsense mediated decay
K7EJ41 -TSL:2CDS 5' incomplete
ENST00000582230.5TOP3A-212588No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000584669.5TOP3A-217580No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000584887.1TOP3A-218545No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000469739.6TOP3A-2033196No protein-
 
Retained intron
--TSL:2
ENST00000583804.2TOP3A-2151465No protein-
 
Retained intron
--TSL:5
ENST00000472959.5TOP3A-204913No protein-
 
Retained intron
--TSL:3
ENST00000583328.5TOP3A-214727No protein-
 
Retained intron
--TSL:2
ENST00000477508.1TOP3A-205600No protein-
 
Retained intron
--TSL:2
ENST00000580713.1TOP3A-209474No protein-
 
Retained intron
--TSL:2