Wnt

Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN. (mesh:D051153)

Cross-references

• MEDSCAN:urn:agi-aopfc:0000426
• BEL:WNT Family
• IP:IPR018161
• IP:IPR005817
• RE:R-HSA-3247824
• MESH:D051153 - Wnt Proteins
• PF:PF00110
• RE:R-HSA-3238268
• RE:R-HSA-3238374
• SIGNOR:SIGNOR-PF40
• SFAM:F0247
• RE:R-HSA-3247790
• RE:R-HSA-3247835
• NXP:FA:04686

Synonyms

Synonym	Reference	Specificity
Wnt		Exact
WNT		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:12780	WNT2	isa
FPLX:Wnt5	Wnt5	isa
HGNC:12775	WNT10B	isa
HGNC:12776	WNT11	isa
HGNC:12774	WNT1	isa
HGNC:16267	WNT16	isa
HGNC:12786	WNT7A	isa
HGNC:12787	WNT7B	isa
HGNC:12781	WNT2B	isa
HGNC:12785	WNT6	isa
HGNC:12788	WNT8A	isa
HGNC:12778	WNT9A	isa
HGNC:13829	WNT10A	isa
HGNC:15983	WNT3A	isa
HGNC:12782	WNT3	isa
HGNC:12783	WNT4	isa
HGNC:12779	WNT9B	isa
HGNC:12789	WNT8B	isa

Outgoing Relations

None available.