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| Status |
Public on Jun 21, 2018 |
| Title |
Differential gene expression in the stellate ganglia of 16 week wistar and spontaneously hypertensive rat samples |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Hypertension remains a poorly understood condition, and the understanding of the sympathetic nervous systems role in this disease remains even more limited. In this study, RNA-sequencing is used to identify transcriptomal differences in the sympathetic stellate ganglia between the 16-week-old normotensive wistar strain and the spontaneously hypertensive rat strain.This dataset should allow for further molecular characterisation of hypertensive changes in a cardiac-innervating sympathetic ganglion.
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| Overall design |
Comparison of normotensive and hypertensive rat stellate ganglia. 4 biological replicates for both 16 week wistar and SHR stellate ganglia samples were contrasted
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| Contributor(s) |
Davis H, Bardsley E, Paterson DJ |
| Citation(s) |
29872217, 29686017 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| OT2 OD023848 |
Comprehensive Structural and Functional Mapping of the Mammalian Cardiac Nervous System |
UNIVERSITY OF CALIFORNIA LOS ANGELES |
David Paterson |
|
| Submission date |
Feb 06, 2018 |
| Last update date |
Aug 13, 2019 |
| Contact name |
David Paterson |
| E-mail(s) |
david.paterson@dpag.ox.ac.uk
|
| Organization name |
University of Oxford
|
| Department |
Department of Physiology, Anatomy and Genetics
|
| Lab |
Paterson Group
|
| Street address |
Parks Road
|
| City |
Oxford |
| ZIP/Postal code |
OX1 3PT |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL22396 |
Illumina HiSeq 4000 (Rattus norvegicus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA433115 |
| SRA |
SRP132271 |
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