Term Information

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Accession
GO:0000253
Name
3-keto sterol reductase activity
Ontology
molecular_function
Synonyms
3-keto-steroid reductase activity, 3-KSR activity, 3beta-hydroxy-steroid:NADP+ 3-oxidoreductase
Alternate IDs
GO:0050576
Definition
Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H+. Source: PMID:9811880, GOC:mah, EC:1.1.1.270
Comment
Note that zymosterol is cholesta-8,24-dien-3-ol.
History
See term history for GO:0000253 at QuickGO
Chem. react.
has participant 3beta-hydroxy steroid
has participant NADP(3-)
has participant 3-oxo steroid
has participant NADPH(4-)
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0000253 from QuickGO

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Parents of 3-keto sterol reductase activity (GO:0000253)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3-keto sterol reductase activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
3-keto sterol reductase activity [RO:0000057 relation] RO:0000057  3beta-hydroxy steroid (CHEBI:36836)
3-keto sterol reductase activity [RO:0000057 relation] RO:0000057  NADP(3-) (CHEBI:58349)
3-keto sterol reductase activity [RO:0000057 relation] RO:0000057  3-oxo steroid (CHEBI:47788)
3-keto sterol reductase activity [RO:0000057 relation] RO:0000057  NADPH(4-) (CHEBI:57783)
3-keto sterol reductase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.