AmiGO 2: Term Details for "response to hypoxia" (GO:0001666)

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Term Information

Accession: GO:0001666
Name: response to hypoxia
Ontology: biological_process
Synonyms: response to hypoxic stress, response to lowered oxygen tension, response to intermittent hypoxia, response to sustained hypoxia
Alternate IDs: None
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. Source: GOC:hjd
Comment: Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
History: See term history for GO:0001666 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to response to hypoxia (excluding "regulates").; Link to all direct and indirect annotations to response to hypoxia (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for response to hypoxia (excluding "regulates").

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GO:0050896 response to stimulus
GO:0008150 biological_process
GO:0009628 response to abiotic stimulus
GO:0070482 response to oxygen levels
GO:0036293 response to decreased oxygen levels
GO:0006950 response to stress
GO:0001666 response to hypoxia
GO:0071456 cellular response to hypoxia
GO:0070483 detection of hypoxia
GO:1990910 response to hypobaric hypoxia

Parents of response to hypoxia (GO:0001666)

subject	relation	object
response to hypoxia	is_a	response to decreased oxygen levels (GO:0036293)
response to hypoxia	is_a	response to stress (GO:0006950)

Children of response to hypoxia (GO:0001666)

subject	relation	object
response to hypobaric hypoxia (GO:1990910)	is_a	response to hypoxia
detection of hypoxia (GO:0070483)	is_a	response to hypoxia
cellular response to hypoxia (GO:0071456)	is_a	response to hypoxia

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