Term Information

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Accession
GO:0004088
Name
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Ontology
molecular_function
Synonyms
carbamoyl phosphate synthase (glutamine-hydrolyzing) activity, CPS activity, GD-CPSase activity, carbamoyl phosphate synthetase activity, carbamoyl-phosphate synthase (glutamine-hydrolysing) activity, carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity, carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity, carbamoylphosphate synthetase II activity, carbamyl phosphate synthetase (glutamine) activity, carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity, glutamine-dependent carbamoyl-phosphate synthase activity, glutamine-dependent carbamyl phosphate synthetase activity, hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity
Alternate IDs
None
Definition
Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate. Source: EC:6.3.5.5, RHEA:18633
Comment
None
History
See term history for GO:0004088 at QuickGO
Chem. react.
has participant ADP(3-)
has participant L-glutamine zwitterion
has participant hydrogenphosphate
has participant hydron
has participant hydrogencarbonate
has participant water
has participant carbamoyl phosphate(2-)
has participant L-glutamate(1-)
has participant ATP(4-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004088 from QuickGO

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Parents of carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (GO:0004088)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  ADP(3-) (CHEBI:456216)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  L-glutamine zwitterion (CHEBI:58359)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  hydrogenphosphate (CHEBI:43474)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  hydrogencarbonate (CHEBI:17544)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  carbamoyl phosphate(2-) (CHEBI:58228)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  L-glutamate(1-) (CHEBI:29985)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [is_a relation] is_a  carbon-nitrogen ligase activity, with glutamine as amido-N-donor (GO:0016884)
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [RO:0000057 relation] RO:0000057  ATP(4-) (CHEBI:30616)
Children of carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (GO:0004088)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
carbamoyl-phosphate synthase complex (GO:0005951) [RO:0002215 relation] RO:0002215  carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EC
6.3.5.5
MetaCyc
CARBPSYN-RXN
Reactome
R-HSA-73577
RHEA
18633