AmiGO 2: Term Details for "phosphoglycerate dehydrogenase activity" (GO:0004617)

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Term Information

Accession: GO:0004617
Name: phosphoglycerate dehydrogenase activity
Ontology: molecular_function
Synonyms: 3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity, 3-phosphoglycerate dehydrogenase activity, 3-phosphoglycerate:NAD+ 2-oxidoreductase activity, 3-phosphoglyceric acid dehydrogenase activity, 3PHP reductase activity, D- and L-HGA, D-3-phosphoglycerate dehydrogenase activity, D-3-phosphoglycerate:NAD+ oxidoreductase activity, PGDH activity, SerA, SerA 3PG dehydrogenase activity, alpha-KG reductase activity, alpha-phosphoglycerate dehydrogenase activity, alphaKG reductase activity, glycerate 3-phosphate dehydrogenase activity, glycerate-1,3-phosphate dehydrogenase activity, phosphoglycerate oxidoreductase activity, phosphoglyceric acid dehydrogenase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+. Source: EC:1.1.1.95
Comment: None
History: See term history for GO:0004617 at QuickGO
Chem. react.: has participant 3-phosphonatooxypyruvate(3-); has participant hydron; has participant NADH(2-); has participant NAD(1-); has participant 3-phosphonato-D-glycerate(3-)
Subset: None
Related: Link to all genes and gene products annotated to phosphoglycerate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations to phosphoglycerate dehydrogenase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for phosphoglycerate dehydrogenase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004617 phosphoglycerate dehydrogenase activity

Parents of phosphoglycerate dehydrogenase activity (GO:0004617)

subject	relation	object
phosphoglycerate dehydrogenase activity	RO:0000057	3-phosphonatooxypyruvate(3-) (CHEBI:18110)
phosphoglycerate dehydrogenase activity	RO:0000057	hydron (CHEBI:15378)
phosphoglycerate dehydrogenase activity	RO:0000057	NADH(2-) (CHEBI:57945)
phosphoglycerate dehydrogenase activity	RO:0000057	NAD(1-) (CHEBI:57540)
phosphoglycerate dehydrogenase activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
phosphoglycerate dehydrogenase activity	RO:0000057	3-phosphonato-D-glycerate(3-) (CHEBI:58272)

This term has no children.

EC: 1.1.1.95
MetaCyc: PGLYCDEHYDROG-RXN
Reactome: R-HSA-977348
RHEA: 12641