Term Information

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Accession
GO:0004632
Name
phosphopantothenate--cysteine ligase activity
Ontology
molecular_function
Synonyms
phosphopantothenate-cysteine ligase activity, phosphopantothenoylcysteine synthetase activity, (R)-4'-phosphopantothenate:L-cysteine ligase activity
Alternate IDs
None
Definition
Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives. Source: EC:6.3.2.5
Comment
None
History
See term history for GO:0004632 at QuickGO
Chem. react.
has participant N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate(3-)
has participant L-cysteine zwitterion
has participant cytidine 5'-monophosphate(2-)
has participant (R)-4'-phosphonatopantothenate(3-)
has participant diphosphate(3-)
has participant hydron
has participant CTP(4-)
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004632 from QuickGO

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Parents of phosphopantothenate--cysteine ligase activity (GO:0004632)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phosphopantothenate--cysteine ligase activity [RO:0000057 relation] RO:0000057  N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate(3-) (CHEBI:59458)
phosphopantothenate--cysteine ligase activity [RO:0000057 relation] RO:0000057  L-cysteine zwitterion (CHEBI:35235)
phosphopantothenate--cysteine ligase activity [RO:0000057 relation] RO:0000057  cytidine 5'-monophosphate(2-) (CHEBI:60377)
phosphopantothenate--cysteine ligase activity [RO:0000057 relation] RO:0000057  (R)-4'-phosphonatopantothenate(3-) (CHEBI:10986)
phosphopantothenate--cysteine ligase activity [RO:0000057 relation] RO:0000057  diphosphate(3-) (CHEBI:33019)
phosphopantothenate--cysteine ligase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
phosphopantothenate--cysteine ligase activity [RO:0000057 relation] RO:0000057  CTP(4-) (CHEBI:37563)
phosphopantothenate--cysteine ligase activity [is_a relation] is_a  acid-amino acid ligase activity (GO:0016881)

This term has no children.

EC
6.3.2.5
MetaCyc
P-PANTOCYSLIG-RXN
Reactome
R-HSA-196753
RHEA
19397