AmiGO 2: Term Details for "superoxide dismutase activity" (GO:0004784)

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Term Information

Accession: GO:0004784
Name: superoxide dismutase activity
Ontology: molecular_function
Synonyms: superoxide:superoxide oxidoreductase activity, Cu,Zn-SOD, Fe-SOD, Mn-SOD, SOD, SOD-1, SOD-2, SOD-3, SOD-4, SODF, SODS, cuprein, cytocuprein, erythrocuprein, hemocuprein, hepatocuprein, iron superoxide oxidoreductase, manganese superoxide oxidoreductase, nickel superoxide oxidoreductase, superoxide dismutase I, superoxide dismutase II, zinc superoxide oxidoreductase, Cu-Zn superoxide dismutase activity, Mn, Fe superoxide dismutase, copper, zinc superoxide dismutase activity, ferrisuperoxide dismutase activity, iron superoxide dismutase activity, manganese superoxide dismutase activity, nickel superoxide dismutase activity
Alternate IDs: GO:0008383, GO:0008382, GO:0016954, GO:0004785
Definition: Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide. Source: GOC:vw, EC:1.15.1.1, PMID:15064408
Comment: None
History: See term history for GO:0004784 at QuickGO
Chem. react.: has participant hydrogen peroxide; has participant hydron; has participant dioxygen; has participant superoxide
Subset: None
Related: Link to all genes and gene products annotated to superoxide dismutase activity (excluding "regulates").; Link to all direct and indirect annotations to superoxide dismutase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for superoxide dismutase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
GO:0008150 biological_process
GO:0051716 cellular response to stimulus
GO:0050896 response to stimulus
GO:0006950 response to stress
UBERON:0001062 anatomical entity
GO:0009987 cellular process
GO:0070887 cellular response to chemical stimulus
GO:0033554 cellular response to stress
CARO:0000006 material anatomical entity
GO:0042221 response to chemical
GO:0062197 cellular response to chemical stress
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0006979 response to oxidative stress
GO:1901700 response to oxygen-containing compound
UBERON:0000061 anatomical structure
GO:0034599 cellular response to oxidative stress
GO:1901701 cellular response to oxygen-containing compound
GO:0008152 metabolic process
GO:0010035 response to inorganic substance
GO:0000302 response to reactive oxygen species
GO:0009636 response to toxic substance
CL:0000000 cell
GO:0044237 cellular metabolic process
GO:0034614 cellular response to reactive oxygen species
GO:0097237 cellular response to toxic substance
GO:0098754 detoxification
GO:0003674 molecular_function
GO:0000305 response to oxygen radical
GO:0003824 catalytic activity
GO:1990748 cellular detoxification
GO:0071450 cellular response to oxygen radical
GO:0072593 reactive oxygen species metabolic process
GO:0000303 response to superoxide
GO:0098869 cellular oxidant detoxification
GO:0071451 cellular response to superoxide
GO:0016491 oxidoreductase activity
GO:0006801 superoxide metabolic process
GO:0016209 antioxidant activity
GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor
GO:0019430 removal of superoxide radicals
GO:0004784 superoxide dismutase activity
GO:1901670 negative regulation of superoxide dismutase activity
GO:1901671 positive regulation of superoxide dismutase activity
GO:1901668 regulation of superoxide dismutase activity
GO:1902693 superoxide dismutase complex

Parents of superoxide dismutase activity (GO:0004784)

subject	relation	object
superoxide dismutase activity	BFO:0000050	removal of superoxide radicals (GO:0019430)
superoxide dismutase activity	RO:0000057	hydrogen peroxide (CHEBI:16240)
superoxide dismutase activity	RO:0000057	hydron (CHEBI:15378)
superoxide dismutase activity	is_a	antioxidant activity (GO:0016209)
superoxide dismutase activity	RO:0000057	dioxygen (CHEBI:15379)
superoxide dismutase activity	RO:0000057	superoxide (CHEBI:18421)
superoxide dismutase activity	is_a	oxidoreductase activity, acting on superoxide radicals as acceptor (GO:0016721)

Children of superoxide dismutase activity (GO:0004784)

subject	relation	object
positive regulation of superoxide dismutase activity (GO:1901671)	RO:0002213	superoxide dismutase activity
superoxide dismutase complex (GO:1902693)	RO:0002215	superoxide dismutase activity
negative regulation of superoxide dismutase activity (GO:1901670)	RO:0002212	superoxide dismutase activity
regulation of superoxide dismutase activity (GO:1901668)	RO:0002211	superoxide dismutase activity

EC: 1.15.1.1
MetaCyc: SUPEROX-DISMUT-RXN
Reactome: R-HSA-3299691; R-HSA-3299680; R-HSA-1222462; R-HSA-3777112; R-HSA-3299682; R-HSA-1222469
RHEA: 20696