AmiGO 2: Term Details for "MAP-kinase scaffold activity" (GO:0005078)

Accession: GO:0005078
Name: MAP-kinase scaffold activity
Ontology: molecular_function
Synonyms: MAP-kinase scaffold protein activity
Alternate IDs: None
Definition: The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently. Source: PMID:15213240, PMID:12511654, PMID:9405336
Comment: None
History: See term history for GO:0005078 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to MAP-kinase scaffold activity (excluding "regulates").; Link to all direct and indirect annotations to MAP-kinase scaffold activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for MAP-kinase scaffold activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
MAP-kinase scaffold activity	is_a	signaling adaptor activity (GO:0035591)
MAP-kinase scaffold activity	BFO:0000051	mitogen-activated protein kinase binding (GO:0051019)
MAP-kinase scaffold activity	BFO:0000050	MAPK cascade (GO:0000165)
MAP-kinase scaffold activity	RO:0002162	Eukaryota (NCBITaxon:2759)

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