Term Information

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Accession
GO:0006098
Name
pentose-phosphate shunt
Ontology
biological_process
Synonyms
hexose monophosphate pathway, pentose phosphate pathway, pentose phosphate shunt, pentose-phosphate pathway
Alternate IDs
None
Definition
The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate). Source: MetaCyc:PENTOSE-P-PWY, ISBN:0198506732, GOC:pde
Comment
None
History
See term history for GO:0006098 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0006098 from QuickGO

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Parents of pentose-phosphate shunt (GO:0006098)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pentose-phosphate shunt [RO:0004009 relation] RO:0004009  NADP(3-) (CHEBI:58349)
pentose-phosphate shunt [RO:0004008 relation] RO:0004008  NADPH(4-) (CHEBI:57783)
pentose-phosphate shunt [RO:0002230 relation] RO:0002230  pentose-phosphate shunt, non-oxidative branch (GO:0009052)
pentose-phosphate shunt [RO:0002224 relation] RO:0002224  pentose-phosphate shunt, oxidative branch (GO:0009051)
pentose-phosphate shunt [is_a relation] is_a  glucose 6-phosphate metabolic process (GO:0051156)
pentose-phosphate shunt [is_a relation] is_a  NADPH regeneration (GO:0006740)
pentose-phosphate shunt [RO:0004009 relation] RO:0004009  beta-D-glucose 6-phosphate(2-) (CHEBI:58247)
Children of pentose-phosphate shunt (GO:0006098)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
pentose-phosphate shunt, non-oxidative branch (GO:0009052) [BFO:0000050 relation] BFO:0000050  pentose-phosphate shunt
regulation of pentose-phosphate shunt (GO:0043456) [RO:0002211 relation] RO:0002211  pentose-phosphate shunt
positive regulation of pentose-phosphate shunt (GO:1905857) [RO:0002213 relation] RO:0002213  pentose-phosphate shunt
negative regulation of pentose-phosphate shunt (GO:1905856) [RO:0002212 relation] RO:0002212  pentose-phosphate shunt
pentose-phosphate shunt, oxidative branch (GO:0009051) [BFO:0000050 relation] BFO:0000050  pentose-phosphate shunt
KEGG_PATHWAY
map00030
MetaCyc
PENTOSE-P-PWY
Reactome
R-HSA-71336
Wikipedia
Pentose_phosphate_pathway